2-(氯甲基)-2,3-二氢-噻吩并[3,4-b]-1,4-二噁英 | 857419-46-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2-(氯甲基)-2,3-二氢-噻吩并[3,4-b]-1,4-二噁英
• 英文名称: 2-chloromethyl-2,3-dihydrothieno[3,4-b][1,4]dioxine
• 英文别名: 2'-chloromethyl-3,4-ethylenedioxythiophene；2-(Chloromethyl)-2,3-dihydrothieno[3,4-b][1,4]dioxine；3-(chloromethyl)-2,3-dihydrothieno[3,4-b][1,4]dioxine
• CAS: 857419-46-6
• 化学式: C₇H₇ClO₂S
• 分子量: 190.65
• InChiKey: UOXHKOVMJCKBOG-UHFFFAOYSA-N

物化性质

• 熔点：
  39-44°C
• 沸点：
  280.5±28.0 °C(Predicted)
• 密度：
  1.359±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  46.7
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• WGK Germany：
  3

反应信息

• 作为反应物：
  描述：

  2-(氯甲基)-2,3-二氢-噻吩并[3,4-b]-1,4-二噁英 在 4-二甲氨基吡啶 、 水 、 三乙胺 、 sodium hydroxide 作用下， 以 二氯甲烷 、 二甲基亚砜 为溶剂， 生成 4-((2,3-dihydrothieno[3,4-b][1,4]dioxin-2-yl)-methoxy)-4-oxobutanoic acid
  参考文献：
  名称：

  Electrochemical sensor based on f-SWCNT and carboxylic group functionalized PEDOT for the sensitive determination of bisphenol A

  摘要：

  A simple, sensitive, and reliable method for the voltammetric determination of bisphenol A (BPA) by using carboxylic group functionalized single-walled carbon nanotubes (f-SWCNT)/carboxylic-functionalized poly(3,4-ethylenedioxythiophene) (PC4) complex modified glassy carbon electrode (GCE) has been successfully developed. The electrochemical behavior of BPA at the surface of the modified electrode is investigated by electrochemical techniques. The cyclic voltammetry results show that the as-prepared electrode exhibits strong catalytic activity toward the oxidation of BPA with a well-defined anodic peak at 0.623 V in PBS (0.1 mol/L, pH 7.0). The surface morphology of the 3D network of composite film is beneficial for the adsorption of analytes. Under the optimized conditions, the oxidation peak current is proportional to BPA concentration in the range between 0.099 and 5.794 mu mol/L (R-2 = 0.9989), with a limit of detection of 0.032 mu mol/L (SIN = 3). The enhanced performance of the sensor can be attributed to the excellent electrocatalytic property of f-SWCNT and the extraordinary conductivity of PC4. Furthermore, the proposed modified electrode displays high stability and good reproducibility. The good result on the voltammetric determination of BPA also indicates that the asfabricated modified electrode will be a good candidate for the electrochemical determination and analysis of BPA. (C) 2013 Xue-Min Duan. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

  DOI：

  10.1016/j.cclet.2013.12.020
• 作为产物：
  描述：

  3,4-二甲氧基噻吩 、 3-氯-1,2-丙二醇 在 对甲苯磺酸 作用下， 以 甲苯 为溶剂， 以61.96%的产率得到2-(氯甲基)-2,3-二氢-噻吩并[3,4-b]-1,4-二噁英
  参考文献：
  名称：

  Synthesis and characterization of monomeric and polymeric Pd(II) and Pt(II) complexes of 3,4-ethylenedioxythiophene-functionalized phosphine ligands

  摘要：

  我们制备了带有 3,4-亚乙二氧基噻吩（EDOT）基团的膦配体及其顺式[MCl2(L)2]（M = Pd 和 Pt）络合物，其中 Ph2P 基团与噻吩环[Ph2P(5-EDOT), 1]直接相连，或通过亚甲基（4）或长（7）"间隔物 "与 EDOT 乙烯桥相连。研究人员对这些络合物与 EDOT 的电化学共聚进行了研究，以期制造出含有共价结合金属膦络合物的导电聚合物。虽然在所有实验中都获得了聚合物涂层电极，但 XPS 测量结果表明，在存在顺式-[MCl2(1)2] 的情况下制成的聚合物仅由聚(3,4-亚乙二氧基噻吩)（PEDOT）组成，而在存在顺式-[MCl2(L)2] （L = 4，7）的情况下制成的聚合物则是真正的共聚物，其中含有钯（II）或铂（II）络合物。

  DOI：

  10.1039/b817210b

文献信息

• SUPEROLEOPHOBIC AND/OR SUPERHYDROPHOBIC MATERIAL, PROCESS FOR PREPARING SAME AND APPLICATIONS THEREOF
  申请人：UNIVERSITE NICE SOPHIA ANTIPOLIS

  公开号：US20160096845A1

  公开（公告）日：2016-04-07

  The invention relates to a multilayer superoleophobic and/or superhydrophobic material comprising: on the one hand, a first constituent that is a conductive substrate or a substrate that has previously been rendered conductive (1): the surface of which is modified by chemical and/or physical treatment (2) and that incorporates a first adhesion-promoting conductive layer (3); or that incorporates a first adhesion-promoting conductive layer (3); and, on the other hand, at least one other constituent that is a superoleophobic and/or superhydrophobic polymer or copolymer layer (4, 5 or 6) composed of one or more monomers based on an aromatic or heteroaromatic ring substituted by one or more fluorocarbon and/or hydrocarbon chains. It is characterized in that the various constituents of said material comply with an increasing hydrophobicity gradient between the first layer deposited on the conductive substrate or substrate previously rendered conductive (1) and the last layer of said material.

  该发明涉及一种多层超疏水和/或超疏油材料，包括：一方面，第一组分是导电基底或已经被处理为导电的基底（1）：其表面经过化学和/或物理处理（2）并且包含第一粘附促进导电层（3）；或者包含第一粘附促进导电层（3）；另一方面，至少另一组分是由一个或多个以芳香或杂芳环为基础的单体构成的超疏水和/或超疏油聚合物或共聚物层（4、5或6），这些单体被一个或多个氟碳和/或烃链取代。其特征在于所述材料的各组分在导电基底或先前被处理为导电的基底（1）上沉积的第一层与所述材料的最后一层之间遵守逐渐增加的疏水性梯度。
• “Click”-functionalization of conducting poly(3,4-ethylenedioxythiophene) (PEDOT)
  作者：Hang-Beom Bu、Günther Götz、Egon Reinold、Astrid Vogt、Sylvia Schmid、Raúl Blanco、Jose L. Segura、Peter Bäuerle

  DOI：10.1039/b718077b

  日期：——

  Efficient post-functionalization of conductive polymer films was achieved by Cu+-catalyzed 'click'-cycloaddition of novel poly(azidomethyl-EDOT) P2 and various functionalized terminal alkynes under mild heterogeneous conditions with high conversion efficiencies.

  通过在温和的异相条件下，采用Cu+催化的新型聚（叠氮甲基-EDOT）P2与各种功能化末端炔烃的‘点击’环加成，实现了导电聚合物薄膜的高效后功能化，具有高转化效率。
• Electrochromic enhancement of poly(3,4-ethylenedioxythiophene) films functionalized with hydroxymethyl and ethylene oxide
  作者：Shimin Zhang、Jingkun Xu、Baoyang Lu、Leiqiang Qin、Long Zhang、Shijie Zhen、Daize Mo

  DOI：10.1002/pola.27206

  日期：2014.7.15

  PEDOT‐MeOH and PEDOT‐MO could be reversibly oxidized and reduced accompany with obvious color changes. Further kinetic studies demonstrated that the introduction of hydroxymethyl or ethylene oxide group significantly improved electrochromic properties of 3,4‐ethylenedioxythiophene (PEDOT) and resulted in high contrast ratios (57.3% at 585 nm) and coloration efficiencies (338.5 cm2 C−1), low switching

  通过表氯醇与羟甲基化的3,4-亚乙基二氧噻吩（EDOT-）反应成功合成了2-（（（2,3-二氢噻吩并[3,4- b ]二恶英-2-基]甲氧基）甲氧基）甲基环氧乙烷（EDOT-MO） MeOH），它是通过简单的四步序列合成的。聚（羟甲基化-3,4-亚乙基二氧基噻吩）（PEDOT-MeOH）和聚（2-（（2,3-二氢噻吩并[3,4- b分别通过EDOT-MeOH和EDOT-MO的电聚合来电合成]二恶英-2-基）甲氧基）甲基环氧乙烷（PEDOT-MO）。通过FTIR，循环伏安法，紫外可见和热重法研究了形成的聚合物的结构，电化学，光学和热学性质。光谱电化学研究表明，PEDOT-MeOH和PEDOT-MO可以被可逆地氧化和还原，并伴有明显的颜色变化。进一步的动力学研究表明，引入羟甲基或环氧乙烷基团可显着改善3,4-乙撑二氧噻吩（PEDOT）的电致变色性能，并具有较高的对比度（585 nm时为57.3％）和着色效率（338
• Synthesis of novel chiral <scp>l</scp>-leucine grafted PEDOT derivatives with excellent electrochromic performances
  作者：Dufen Hu、Baoyang Lu、Xuemin Duan、Jingkun Xu、Long Zhang、Kaixin Zhang、Shimin Zhang、Shijie Zhen

  DOI：10.1039/c4ra05075d

  日期：——

  PEDOT–Boc–Leu and PEDOT–Leu exhibit excellent electrochromic performance, and are promising optoelectronic materials.

  PEDOT-Boc-Leu和PEDOT-Leu表现出优异的电致变色性能，是有前途的光电材料。
• 一种唾液酸识别导电高分子前驱体的制备方 法
  申请人：内蒙古民族大学

  公开号：CN109721621B

  公开（公告）日：2021-01-15

  本发明公开了一种唾液酸识别导电高分子前驱体的制备方法，其特征在于，包括以下步骤：(1)、在氮气气氛下，将28ml的甲苯、10.4mmol的3，4‑二甲氧基噻吩、23.1mmol的3‑氯‑1，2‑丙二醇、0.92mmol对甲苯磺酸一水合物加入双颈烧瓶中，混合并在90℃的条件下反应24h。本发明具有如下优点：本发明合成制备了柔性、肿瘤细胞特异性识别导电高分子材料，实现了对肿瘤细胞的非标示，非侵袭特异性识别，将为恶性肿瘤筛查，癌症早期诊断，即时诊断提供有效手段。