1,2-二溴-1,1,2-三氯乙烷 | 13749-38-7

• 物质功能分类: 有机原料 - 烃类化合物及其衍生物 - 烃类卤化物
• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 中文名称: 1,2-二溴-1,1,2-三氯乙烷
• 英文名称: 1,2-dibromo-1,1,2-trichloroethane
• 英文别名: 1,2-dibromo-1,1,2-trichloro-ethane；1,2-Dibrom-1,1,2-trichlor-aethan；trichloroethylene dibromide；1,2-dibromotrichloroethane
• CAS: 13749-38-7
• 化学式: C₂HBr₂Cl₃
• 分子量: 291.197
• InChiKey: VXKOVUFOVCJHBA-UHFFFAOYSA-N

物化性质

• 沸点：
  94-95 °C10 mm Hg(lit.)
• 密度：
  1.701 g/mL at 25 °C(lit.)
• 闪点：
  >230 °F

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  7
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 危险品标志：
  Xi
• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• 海关编码：
  2903799090
• 安全说明：
  S26,S36

SDS

Name:	1 2-Dibromo-1 1 2-trichloroethane 97% Material Safety Data Sheet
Synonym:
CAS:	13749-38-7

Section 1 - Chemical Product MSDS Name:1 2-Dibromo-1 1 2-trichloroethane 97% Material Safety Data Sheet
Synonym:

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
13749-38-7	1,2-Dibromo-1,1,2-trichloroethane	97%	237-330-1

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
High vapor concentrations may cause drowsiness. May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

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Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use extinguishing media most appropriate for the surrounding fire.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container.

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Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid
Appearance: colourless
Odor: mild ether-like odor
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: > 200 deg C (> 392.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C2HBr2Cl3
Molecular Weight: 291.174

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable.
Conditions to Avoid:
Incompatible materials, excess heat, temperatures above 200C.
Incompatibilities with Other Materials:
Metals, oxidizing agents, lithium, titanium, manganese.
Hazardous Decomposition Products:
Hydrogen chloride, phosgene, hydrogen bromide.
Hazardous Polymerization: Will not occur.

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 13749-38-7 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
1,2-Dibromo-1,1,2-trichloroethane - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
See actual entry in RTECS for complete information.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 13749-38-7: No information available.
United Kingdom Occupational Exposure Limits
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 13749-38-7 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
US FEDERAL
TSCA
CAS# 13749-38-7 is not listed on the TSCA inventory.
It is for research and development use only.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  1,2-二溴-1,1,2-三氯乙烷 在 一氟化氯 作用下， 以89%的产率得到2-溴-1,1,2-三氯-1-氟乙烷
  参考文献：
  名称：

  Boguslavskaya, L. S.; Chuvatkin, N. N.; Panteleeva, I. Yu., Journal of Organic Chemistry USSR (English Translation), 1982, vol. 18, # 5, p. 814 - 820

  摘要：

  DOI：
• 作为产物：
  描述：

  三氯乙烯 在 溴 作用下， 反应 24.0h， 以75%的产率得到1,2-二溴-1,1,2-三氯乙烷
  参考文献：
  名称：

  甲醇和硫代离子取代简单溴（氯）烯烃的分子内Geminal和Vicinal元素效应。一步替代的示例？

  摘要：

  分子内元素效应k（Br）/ k（Cl）替代双溴氯代烯烃BrC（Cl）= C（Br）Cl（1），BrC（Cl）= CCl（2）（2），Me（2）C =研究了C（Br）Cl（3）和XCH = C（Br）Cl（X = Cl，4; X = Br，5），以及MeO（-）和RS（-）亲核试剂。3没有给出取代，而4和5通过最初的消除（至乙炔）加成路线被MeO（-）取代，随后进行了进一步的反应。在4与硫醇盐的反应中，获得2-10的双生元素效应。RSC（Cl）＝ C（Cl）Y，Y ＝ SR，Br的形成是由于最初的嗜盐反应，随后将RSCl加到形成的乙炔中。2与MeO（-）的反应产生较高的邻位元素效应，而RS（-）产生较高的双生元素效应。1与MeO（-）和RS（-）离子的反应产生了高（2个数量级）的宝石元素效应，其被解释为表明决定速率的CX键裂解。高的k（Br）/ k（Cl）分子间元素效应（k（1）/ k（Cl（2）C

  DOI：

  10.1021/jo9709357
• 作为试剂：
  描述：

  氯乙烯 在 1,2-二溴-1,1,2-三氯乙烷 作用下， 生成 1,4-dibromo-1,3-dichloro-butane
  参考文献：
  名称：

  Bromine telomerization

  摘要：

  DOI：

  10.1021/jo01274a036

文献信息

• Process for brominating side chain of m-phenoxytoluene
  申请人：Toyo Soda Manufacturing Co., Ltd.

  公开号：US04393246A1

  公开（公告）日：1983-07-12

  A side chain of m-phenoxytoluene is brominated with a polyhalogenated ethane having the formula ##STR1## wherein W and Z respectively represent Cl or Br and X and Y respectively represent Cl, Br or H, as a brominating agent in a liquid phase in the presence of an amorphous carbon.

  将m-苯氧基甲苯的侧链与具有##STR1##式的多卤代乙烷进行溴化反应，其中W和Z分别表示Cl或Br，X和Y分别表示Cl、Br或H，作为液相中的溴化剂，在无定形碳的存在下。
• Nicodemus, Journal fur praktische Chemie (Leipzig 1954), 1911, vol. <2>83, p. 316
  作者：Nicodemus

  DOI：——

  日期：——
• Fibreoptic intubation through a laryngeal mask airway facilitated by a guide wire
  作者：M. B. Walburn、J. Cornes、I. G. Ryder

  DOI：10.1046/j.1365-2044.2000.01727-7.x

  日期：2000.10
• Mailhe, vol. 18, p. 10911
  作者：Mailhe

  DOI：——

  日期：——
• Manufacture of trifluorochloroethylene
  申请人：KELLOGG M W CO

  公开号：US02667518A1

  公开（公告）日：1954-01-26

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