lithium trifluoroacetate | 2923-17-3

• 物质功能分类: 有机原料 - 有机金属类化合物 - 有机锂
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: lithium trifluoroacetate
• 英文别名: lithium;2,2,2-trifluoroacetate
• CAS: 2923-17-3
• 化学式: C₂F₃O₂*Li
• 分子量: 119.957
• InChiKey: HSFDLPWPRRSVSM-UHFFFAOYSA-M

物化性质

• 熔点：
  250℃
• 密度：
  1.743
• 稳定性/保质期：

  遵循规定使用和储存，则不会发生分解。

计算性质

• 辛醇/水分配系数(LogP)：
  -3.7
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  40.1
• 氢给体数：
  0
• 氢受体数：
  5

安全信息

• TSCA：
  Yes
• 危险等级：
  6.1
• 危险品标志：
  Xi,T
• 安全说明：
  S26
• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• 海关编码：
  2915900090
• 危险标志：
  GHS06,GHS09
• 危险性描述：
  H300,H400
• 储存条件：
  存于阴凉干燥处

SDS

Name:	Trifluoroacetic Acid Lithium Salt 95% Material Safety Data Sheet
Synonym:	None
CAS:	2923-17-3

Section 1 - Chemical Product MSDS Name:Trifluoroacetic Acid Lithium Salt 95% Material Safety Data Sheet
Synonym:None

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
2923-17-3	Trifluoroacetic Acid Lithium Salt	95%	220-878-0

Hazard Symbols: XI
Risk Phrases: 36/37/38

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.Hygroscopic (absorbs moisture from the air).The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Inhalation:
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

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Section 4 - FIRST AID MEASURES
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 2923-17-3: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C2F3LiO2
Molecular Weight: 119.96

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid:
Incompatible materials, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Moisture, strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, hydrogen fluoride gas.
Hazardous Polymerization: Has not been reported

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 2923-17-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Trifluoroacetic Acid Lithium Salt - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 37/39 Wear suitable gloves and eye/face
protection.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 2923-17-3: No information available.
Canada
CAS# 2923-17-3 is listed on Canada's NDSL List.
CAS# 2923-17-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 2923-17-3 is listed on the TSCA inventory.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为反应物：
  描述：

  lithium trifluoroacetate 在 水 作用下， 生成 二氧化碳
  参考文献：
  名称：

  Spectroscopy of Hydrothermal Reactions 22. The Effects of Cations on the Decarboxylation Kinetics of Trifluoroacetate, Cyanoacetate, Propiolate, and Malonate Ions

  摘要：

  The effect of Group 1 counterions on the decarboxylation rate of four carboxylate ions (trifluoroacetate, propiolate, cyanoacetate, and malonate) was determined in water at 140-280 degreesC and 275 bar. The decarboxylation kinetics were determined in real time by using IR spectroscopy and a titanium cell flow-reactor with sapphire windows. The complexity of the reaction of CF3CO2- necessitated additional postreaction studies by H-1 and F-19 NMR spectroscopy and F- ion electrochemistry. Batch mode reactions in a titanium tube reactor were employed for the latter studies. The CF3H product of CF3CO2- decomposed, liberating F- ions. The cation effect for CF3CO2- is caused primarily by the reaction of F- with the. Group I cations in the order Li+ > Na+ > K+..., which changed the ionic strength. The rate of decarboxylation of cyanoacetate was unaffected by the cation, whereas the Li+ ion slowed the rate of decarboxylation of propiolate, perhaps because of complexation with propiolate. These results were compared with the previously investigated malonate system. Where a cation effect was observed, the effect could be attributed to some form of ion pairing, but in each case the details of the interaction differ slightly.

  DOI：

  10.1021/jp020941t
• 作为产物：
  描述：

  三氟乙酸 在 lithium carbonate 作用下， 以 水 为溶剂， 反应 0.5h， 以67%的产率得到lithium trifluoroacetate
  参考文献：
  名称：

  碱金属三氟乙酸盐用于富勒烯的亲核三氟甲基化

  摘要：

  富勒烯C 60容易与三氟乙酸钾和三氟乙酸铯反应生成C 60（CF 3）– M +盐，随后酸水解得到邻位-C 60（CF 3）H。反应速率和替代反应途径的可能性在很大程度上取决于特定的金属阳离子。因此，与降低的热稳定性相关，反应性以Li ＜Na ＜K≈Cs的顺序增加。此外，钠盐，特别是锂盐倾向于影响CF 2-而不是CF 3。-根据硬/软酸和碱理论对富勒烯进行-官能化。发现亲核三氟甲基化适用于其他原始的富勒烯，如C 70以及富勒烯衍生物，如p 7 mp -C 70（CF 3）10。通过在精确控制的溶液相条件下进行区域选择性连续的三氟甲基化，可以选择性地制备低级三氟甲基化的富勒烯。

  DOI：

  10.1016/j.jfluchem.2019.109344
• 作为试剂：
  描述：

  五甲基苯 、 thallium(III) trifluoroacetate 在 lithium trifluoroacetate 作用下， 以 三氟乙酸 为溶剂， 生成
  参考文献：
  名称：

  芳香族的动力学和机理。竞争亲电和电子转移途径的鉴定和证明

  摘要：

  多甲基苯三氟乙酸盐三氟乙酸铊反应练习曲

  DOI：

  10.1021/ja00335a039

文献信息

• RARE EARTH-BASED NANOPARTICLE MAGNETIC RESONANCE CONTRAST AGENT AND PREPARATION METHOD THEREOF
  申请人：PEKING UNIVERSITY

  公开号：US20170196997A1

  公开（公告）日：2017-07-13

  A rare earth-based nanoparticle magnetic resonance contrast agent and a preparation method thereof are provided. The rare earth-based nanoparticle magnetic resonance contrast agent is rare earth-based inorganic nanoparticles having the surfaces coated with hydrophilic ligands. The rare earth-based nanoparticles are first obtained by a high-temperature oil phase reaction, and then the surfaces thereof are coated with hydrophilic molecules to obtain the rare earth-based nanoparticle magnetic resonance contrast agent. Compared with the existing clinical contrast agent, the magnetic resonance contrast agent of the present invention has a greatly improved relaxivity, a good imaging effect, a low required injection dose, and long in vivo residence time. In addition, the rigid structure of the inorganic nanoparticles can effectively reduce the leakage possibility of gadolinium ions.

  提供一种基于稀土的纳米颗粒磁共振造影对比剂及其制备方法。该基于稀土的纳米颗粒磁共振造影对比剂是表面涂覆有亲水性配体的稀土基无机纳米颗粒。首先通过高温油相反应获得这些基于稀土的纳米颗粒，然后将其表面涂覆亲水性分子以获得基于稀土的纳米颗粒磁共振造影对比剂。与现有的临床对比剂相比，本发明的磁共振造影对比剂具有大大提高的弛豫率、良好的成像效果、低的注射剂量要求和长的体内滞留时间。此外，无机纳米颗粒的刚性结构可以有效降低钆离子泄漏的可能性。
• 一种不对称合成含三氟甲基手性季碳化合物 的方法
  申请人：中国农业大学

  公开号：CN104744394B

  公开（公告）日：2017-04-05

  本发明属于有机合成方法技术领域，特别涉及一种不对称合成含三氟甲基手性季碳化合物的方法。本发明方法采用不对成催化Michael加成反应，在有机溶剂中，在双噁唑啉手性配体和镍催化剂的催化下，三氟甲基硝基烯与2‑乙酰基氮杂芳香化合物反应不对称合成(R)‑3‑三氟甲基‑3‑硝基甲基‑1‑(氮杂芳香环‑2‑基)‑丁‑1‑酮。本发明方法反应产率高，光学纯度高。本发明方法可作为提供三氟甲基季碳手性中心化合物的制备工具。
• Synthesis and characterization of lithium-salt complexes with difluoroalkoxyborates for application as lithium electrolytes
  作者：E. Zygadło-Monikowska、Z. Florjańczyk、J. Ostrowska、A. Tomaszewska、P. Bołtromiuk、N. Langwald、D. Golodnitsky、E. Peled

  DOI：10.1016/j.electacta.2015.03.019

  日期：2015.9

  properties of ionic liquids at ambient temperature. On the basis of NMR, FTIR and EIS spectroscopy, the course of the complexation reaction has been proposed and the properties of the salts obtained have been determined. The system with CF3COOLi has the highest ambient-temperature ionic conductivity of the carboxylic complex salts studied (on the order of 10−4 S cm−1). The product of the reaction of CH3(OCH2CH2)2OBF2

  我们提出了一种合成方法，该方法用于合成酸度低于BF 3：ROBF 2的路易斯酸（其中R是包含1至7个环氧乙烷（EO）单体单元的低聚氧乙烯取代基）。合成包括在减压下热分解三氟烷氧基硼酸盐。将合成的衍生物与LiF，LiI，LiPF 6 CH 3 COOLi，CF 3 COOLi和（COOLi）2等低分子量锂盐进行络合反应。所获得的盐在环境温度下显示出离子液体的性质。基于NMR，FTIR和EIS光谱学，提出了络合反应的过程并确定了所得盐的性质。具有CF 3 COOLi的系统在所研究的羧酸络合盐中具有最高的环境温度离子电导率（约为10 -4 S cm -1）。CH的反应的产物3（OCH 2 CH 2）2 OBF 2和的LiI，在固体聚合物电解质（10摩尔％PEO）施加，其特点是在10的数量级的离子电导率-6  - 10 -3 厘米在20 − 90°C的温度范围内为-1，并且锂转移数较高（0.80 −
• 一种合成六氟丙酮的新工艺
  申请人：张江南

  公开号：CN111393287A

  公开（公告）日：2020-07-10

  本发明公开了一种合成六氟丙酮的新工艺，首先将三氟醋酸酐与金属氟化物在溶剂中反应得到三氟乙酰氟，然后加入碱性盐和三氟乙酸盐，三氟乙酸盐与三氟乙酰氟发生偶联反应得产物六氟丙酮，产品收率在95％以上，产品纯度高于96％。
• 2,2`-二（三氟甲基）-4,4`,5,5`-联苯二酐的制备方法
  申请人：江苏尚莱特医药化工材料有限公司

  公开号：CN106699709A

  公开（公告）日：2017-05-24

  本发明公开了一种2,2'‑二（三氟甲基）‑4,4',5,5'‑联苯二酐的制备方法，它是以3,3',4,4'‑四甲基联苯为起始原料，经与卤化剂进行卤代反应得到中间体Ⅱ；然后与三氟乙酸盐进行取代反应得到2,2'‑二（三氟甲基）‑4,4',5,5'‑四甲基联苯；再氧化得到2,2'‑二（三氟甲基）‑4,4',5,5'‑联苯四甲酸；最后脱水成酐得到2,2'‑二（三氟甲基）‑4,4',5,5'‑联苯二酐。本发明的制备方法合成路线较短，总收率较高，而且原料3,3',4,4'‑四甲基联苯价廉易得，从而可以实现低成本化生产，适合工业化大生产。