葡萄糖二酸 | 5793-88-4

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 葡萄糖二酸
• 中文别名: D-蔗糖酸钙；糖二酸钙
• CAS: 5793-88-4
• 化学式: C6H10CaO8
• 分子量: 250.22
• InChiKey: PPEJDNOHLPAGQR-SBBOJQDXSA-N

物化性质

• LogP：
  -1.456 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  -3.78
• 重原子数：
  15
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  156
• 氢给体数：
  6
• 氢受体数：
  8

安全信息

• 危险类别码：
  R36/37/38
• 安全说明：
  S26,S36

文献信息

• [EN] PROCESS FOR MAKING ESTERS OF 2,5-FURANDICARBOXYLIC ACID<br/>[FR] PROCÉDÉ DE FABRICATION D'ESTERS DE L'ACIDE 2,5-FURANDICARBOXYLIQUE
  申请人：ARCHER DANIELS MIDLAND CO

  公开号：WO2018236948A1

  公开（公告）日：2018-12-27

  The present invention relates to a process for making the esters of 2,5-furandicarboxylic acid, and particularly the dimethyl, diethyl or dipropyl esters of FDCA for use as monomers in the production of polyesters and other types of polymers with biobased content, comprising: reacting an aqueous feed comprising glucaric acid with a high boiling first alcohol in the presence of an acid catalyst and with removing water during the reaction, to form a first product mixture comprising a first ester of FDCA and the high boiling first alcohol; removing unreacted high boiling first alcohol from the first product mixture; combining the first ester of FDCA and the high boiling first alcohol with a lower boiling second alcohol selected from the group consisting of methanol, ethanol, isopropanol and n-propanol; transesterifying the first ester with the lower boiling second alcohol to form a second product mixture comprising a second ester of FDCA with the lower boiling second alcohol; and recovering the second ester of FDCA with the lower boiling second alcohol.

  本发明涉及一种制备2,5-呋喃二甲酸酯的方法，特别是制备用作聚酯和其他含生物基成分的聚合物单体的二甲基、二乙基或二丙基呋喃二甲酸酯的方法，包括：在酸催化剂存在下，将含有葡萄糖酸的水性原料与高沸点第一醇反应，并在反应过程中去除水，以形成含有第一呋喃二甲酸酯和高沸点第一醇的第一产物混合物；从第一产物混合物中去除未反应的高沸点第一醇；将第一呋喃二甲酸酯和高沸点第一醇与从甲醇、乙醇、异丙醇和正丙醇组成的低沸点第二醇混合；将第一呋喃二甲酸酯与低沸点第二醇进行酯交换反应，以形成含有第二呋喃二甲酸酯和低沸点第二醇的第二产物混合物；并回收含有第二呋喃二甲酸酯和低沸点第二醇的产物。
• Process for making esters of 2,5-furandicarboxylic acid
  申请人：Archer Daniels Midland Company

  公开号：US11078174B2

  公开（公告）日：2021-08-03

  A process is provided for making esters of FDCA, in which an aqueous feed comprising glucaric acid is first reacted with a high boiling first alcohol in the presence of an acid catalyst and with removing water during the reaction, to form a first product mixture comprising a first ester of FDCA and the high boiling first alcohol, then unreacted high boiling first alcohol is removed from the first product mixture. The first ester of FDCA and the high boiling first alcohol is then transesterified with a lower boiling second alcohol selected from the group consisting of methanol, ethanol, isopropanol and n-propanol, to form a second product mixture comprising a second ester of FDCA with the lower boiling second alcohol, and the second ester of FDCA with the lower boiling second alcohol is recovered.

  本发明提供了一种制造 FDCA 酯的工艺，在该工艺中，首先在酸催化剂存在下，将包含葡 萄酸的水性进料与高沸点第一醇反应，并在反应过程中除去水，以形成包含 FDCA 第一酯和高 沸点第一醇的第一产品混合物，然后从第一产品混合物中除去未反应的高沸点第一醇。然后将 FDCA 第一酯和高沸点第一醇与选自甲醇、乙醇、异丙醇和正丙醇的低沸点第二醇进行酯交换反应，形成由 FDCA 第二酯和低沸点第二醇组成的第二产物混合物，并回收 FDCA 第二酯和低沸点第二醇。
• PROCESS FOR MAKING ESTERS OF 2,5-FURANDICARBOXYLIC ACID
  申请人：Archer Daniels Midland Company

  公开号：EP3642190A1

  公开（公告）日：2020-04-29
• [EN] ARGININE SACCHARATE AND USE THEREOF<br/>[FR] SACCHARATE D'ARGININE ET UTILISATION CORRESPONDANTE
  申请人：NUTRITION 21 INC

  公开号：WO2002008175A2

  公开（公告）日：2002-01-31

  Arginine saccharate and its use in the prevention and treatment of cardiovascular and circulatory disorders such as atherosclerosis and hypertension. The compound is synthesized by mixing arginine with a salt of saccharic acid. Pharmaceutical formulations comprising arginine saccharate are administered parenterally or orally.