木犀草素-3'-葡萄糖醛酸苷 | 53527-42-7

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 黄酮类化合物
• 中文名称: 木犀草素-3'-葡萄糖醛酸苷
• 中文别名: 木犀草素-3'-O-beta-D-葡萄糖醛酸苷
• 英文名称: Luteolin 3'-o-glucuronide
• 英文别名: (2S,3S,4S,5R,6S)-6-[5-(5,7-dihydroxy-4-oxochromen-2-yl)-2-hydroxyphenoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
• CAS: 53527-42-7
• 化学式: C₂₁H₁₈O₁₂
• 分子量: 462.4
• InChiKey: JDOFZOKGCYYUER-ZFORQUDYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  33
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  203
• 氢给体数：
  7
• 氢受体数：
  12

文献信息

• Compositions that treat or inhibit pathological conditions associated with inflammatory response
  申请人：Metaproteomics, LLC

  公开号：EP2221052A2

  公开（公告）日：2010-08-25

  The present invention relates to the use of a composition comprising an effective amount of a compound selected from the group consisting of dihydro-isohumulone, dihydro-isocohumulone, dihydro-isoadhumulone, tetrahydro-isohumulone, tetrahydro-isocohumulone, tetrahydro-isoadhumulone, hexahydro-isohumulone, hexahydro-isocohumulone, and hexahydro-isoadhumulone, in the manufacture of a therapeutic composition for treating or preventing inflammatory or inflammation-associated disorders.

  本发明涉及一种组合物的用途，该组合物含有有效量的选自以下组别的化合物：二氢-异胡麻酮、二氢-异胡麻酮、二氢-异胡麻酮、四氢-异胡麻酮、四氢-异胡麻酮、六氢-异胡麻酮、六氢-异胡麻酮和六氢-异胡麻酮、四氢-异胡芦巴内酯、四氢-异胡芦巴内酯、六氢-异胡芦巴内酯、六氢-异胡芦巴内酯和六氢-异胡芦巴内酯。
• Composition of curcumagalactomannoside and hops extract
  申请人：Metagenics, Inc.

  公开号：US11026897B2

  公开（公告）日：2021-06-08

  A composition for treatment of inflammation in a mammal is provided. The mammal has a neutrophil to lymphocyte ratio (NLR). The composition includes a curcumagalactomannoside and a hops extract. The curcumagalactomannoside and the hops extract cooperate to decrease the NLR of the mammal 12 weeks after ingestion of the composition. A method of treatment of inflammation in a mammal is also provided. The method includes obtaining a parameter of the mammal. The method further includes dosing the composition based on the parameter. The method further includes administering the composition to the mammal.

  提供了一种用于治疗哺乳动物炎症的组合物。哺乳动物的中性粒细胞与淋巴细胞比率（NLR）。该组合物包括姜黄半乳甘露糖苷和啤酒花提取物。姜黄半乳甘露糖苷和啤酒花提取物可在哺乳动物摄入组合物 12 周后协同降低其 NLR。还提供了一种治疗哺乳动物炎症的方法。该方法包括获得哺乳动物的参数。该方法还包括根据参数给组合物配料。该方法还包括向哺乳动物施用组合物。
• Anti-inflammatory pharmaceutical compositions for reducing inflammation and the treatment of prevention of gastric toxicity
  申请人：Babish G. John

  公开号：US20060141082A1

  公开（公告）日：2006-06-29

  The invention provides hops ( Humulis lupulus ) extracts or derivatives thereof for use in treating a patient prophylactically and/or therapeutically for ulcerogenic-type disorders of the stomach and/or intestines. The ulcerogenic disorders can be of the type chemically induced, environmentally-induced, infection-induced, and/or stress-induced. The invention also provides a pharmaceutical composition comprising an active amount of hops extracts or derivatives thereof, in combination with an analgesic compound and/or an anti-inflammatory compound. The invention further provides for use of hops extracts or derivatives thereof, significantly reducing and/or therapeutically treating ulcerogenic-type disorders of the stomach and/or intestines.

  本发明提供了啤酒花 Humulis lupulus )提取物或其衍生物，用于预防和/或治疗胃和/或肠的溃疡型疾病。致溃疡性疾病可以是化学诱导型、环境诱导型、感染诱导型和/或压力诱导型。本发明还提供了一种药物组合物，其中包含有效量的啤酒花提取物或其衍生物，并与镇痛化合物和/或抗炎化合物结合使用。本发明进一步提供了啤酒花提取物或其衍生物的用途，可显著减少和/或治疗胃和/或肠的溃疡型疾病。
• FOODS AND BEVERAGES CONTAINING ANTHOCYANINS STABILIZED BY PLANT EXTRACTS
  申请人：Naturex Inc.

  公开号：EP0859557B1

  公开（公告）日：2007-03-21
• ANTI-INFLAMMATORY PHARMACEUTICAL COMPOSITIONS FOR REDUCING INFLAMMATION AND THE TREATMENT OR PREVENTION OF GASTRIC TOXICITY
  申请人：Metaproteomics, LLC

  公开号：EP1626731B1

  公开（公告）日：2009-01-21