2,6-二甲基-2,5-辛二烯-8-醇 | 16750-94-0

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 2,6-二甲基-2,5-辛二烯-8-醇
• 英文名称: 2,6-dimethyl-2,5-octadien-8-ol
• 英文别名: (3E)-3,7-dimethyl-octa-3,6-dien-1-ol；trans-β-isogeraniol；(E)-iso-geraniol；E-isogeraniol；Isogeraniol；3,7-dimethyl-oct-3,6-dienol；(3E)-3,7-dimethylocta-3,6-dien-1-ol
• CAS: 16750-94-0
• 化学式: C₁₀H₁₈O
• 分子量: 154.252
• InChiKey: DTHIOPUFUOMHAY-UXBLZVDNSA-N

物化性质

• 保留指数：
  1812

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2,6-二甲基-2,5-辛二烯-8-醇 在 chromium(VI) oxide 、 硫酸 、 三乙胺 、 lithium diisopropyl amide 作用下， 以 四氢呋喃 、 正己烷 、 水 、 丙酮 为溶剂， 反应 2.58h， 生成 (R)-4-Benzyl-3-{(E)-(S)-2-[(1S,2R)-1-hydroxy-2-(4-methoxy-benzyloxy)-4-phenylselanyl-butyl]-3,7-dimethyl-octa-3,6-dienoyl}-oxazolidin-2-one
  参考文献：
  名称：

  A New, Ring Closing Metathesis-Based Synthesis of (−)-Fumagillol

  摘要：

  [GRAPHICS]A new strategy to access the fumagillin/fumagillol skeleton is proposed. An Evans aldolization and a RCM involving an enone are used for the preparation of a key cyclohexanone intermediate, which was readily converted to fumagillol. The synthesis also features an efficient preparation of isogeraniol and isogeranic acid.

  DOI：

  10.1021/ol016343z
• 作为产物：
  描述：

  1-氯-3-甲基-2-丁烯 在 六甲基磷酰三胺 、 正丁基锂 、 sodium 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 31.5h， 生成 2,6-二甲基-2,5-辛二烯-8-醇
  参考文献：
  名称：

  Synthesis of dolichol-type (S)-hexa- and (S)-heptaprenols

  摘要：

  DOI：

  10.1007/bf00957785

文献信息

• [EN] 3-(2-ALKOXYCARBONYLOXY-PHENYL) ACRYLIC ACID ESTERS AND THEIR USE AS PRECURSORS FOR THE DELIVERY OF OLFACTORY COMPOUNDS<br/>[FR] ESTERS D'ACIDE 3-(2-ALCOXYCARBONYLOXY-PHENYL) ACRYLIQUE ET LEUR UTILISATION COMME PRECURSEURS POUR L'ADMINISTRATION DE COMPOSES OLFACTIFS
  申请人：GIVAUDAN SA

  公开号：WO2005077881A1

  公开（公告）日：2005-08-25

  A compound of formula (I), their use as precursors and a method of their production wherein n, Y, R, R2, R3, and R4 has the same meaning as given in the specification.

  一种具有式（I）的化合物，它们作为前体的用途以及它们的制备方法，其中n、Y、R、R2、R3和R4的含义与规范中给出的含义相同。
• [EN] 3'-KETOGLYCOSIDE COMPOUND FOR THE SLOW RELEASE OF A VOLATILE ALCOHOL<br/>[FR] COMPOSÉ 3'-CÉTOGLYCOSIDE POUR LA LIBÉRATION LENTE D'UN ALCOOL VOLATIL
  申请人：GLYCOSCIENCE S L

  公开号：WO2021160670A1

  公开（公告）日：2021-08-19

  The present invention relates to a 3'-ketoglycoside compound defined by formula (I) and its use for controlled release of alcohols, in particular alcohols showing an insect repellent effect. It relates also to a process for preparing the 3'-ketoglycoside compound of formula (I). It further relates to a composition comprising a 3'- ketoglycoside compound of formula (I). It relates also to the use of a 3'-ketoglycoside compound of formula (I) for the controlled release of alcohols. It related also to a method of use of such composition.

  本发明涉及由式(I)定义的3'-酮基糖苷化合物及其用于控制释放醇，特别是显示驱虫效果的醇。它还涉及制备式(I)的3'-酮基糖苷化合物的方法。此外，它还涉及包含式(I)的3'-酮基糖苷化合物的组合物。它还涉及使用式(I)的3'-酮基糖苷化合物来控制释放醇。它还涉及使用这种组合物的方法。
• [EN] PRO-PERFUME COMPOSITIONS<br/>[FR] COMPOSITIONS DE PROPARFUM
  申请人：FIRMENICH & CIE

  公开号：WO2021123144A1

  公开（公告）日：2021-06-24

  The present invention relates to a perfuming composition comprising at least two properfume compounds selected from the group consisting of a pro-perfume compound releasing a perfume compound upon exposure to light, a pro-perfume compound releasing a perfume compound upon exposure to air/oxygen, a pro-perfume compound releasing a perfume compound upon exposure to heat, a pro-perfume compound releasing a perfume compound upon exposure to moisture and a pro-perfume compound releasing a perfume compound upon exposure to enzymes. The present invention further concerns a perfumed consumer product comprising the inventive perfuming composition, as well as the use of the inventive perfuming composition for improving, enhancing, conferring and/or modifying the fragrance impression and/or fragrance intensity of a consumer product.

  本发明涉及一种香水组合物，包括至少两种从以下组成的适当香气化合物中选择的香气化合物：一种在光照下释放香水化合物的前香水化合物，一种在空气/氧气暴露下释放香水化合物的前香水化合物，一种在热暴露下释放香水化合物的前香水化合物，一种在湿气暴露下释放香水化合物的前香水化合物以及一种在酶暴露下释放香水化合物的前香水化合物。本发明进一步涉及一种含有创新香水组合物的香水消费产品，以及使用创新香水组合物来改善、增强、赋予和/或修改消费产品的香气印象和/或香气强度。
• An efficient reduction system - NiCl2·6H2O-Zn/DMF-H2O for conversion of aldehydes to alcohols
  作者：Robindra N. Baruah

  DOI：10.1016/s0040-4039(00)79109-x

  日期：1992.9

  Aldehydes were efficiently converted to the corresponding alcohols at room temperature, with NiCl2·6H2O-Zn/DMF-H2O system.

  使用NiCl 2 ·6H 2 O-Zn / DMF-H 2 O体系在室温下将醛有效地转化为相应的醇。
• Esters comprising a secondary carbamoyl function and their use as odorant alcohol precursors
  申请人：——

  公开号：US20020144360A1

  公开（公告）日：2002-10-10

  The compounds of the formula 1 in which the dotted line indicates the location of a single or double bond; R 1 represents a radical derived from an odoriferous alcohol of the formula R 1 OH; R 2 represents a hydrogen atom, a linear or branched, saturated or unsaturated C 1 -C 30 hydrocarbon radical, or an aliphatic or aromatic cyclic compound having 5 or 6 carbon atoms, this radical R 2 possibly comprising heteroatoms of oxygen, sulphur or nitrogen; the symbols R 3 , R 4 and R 4 ′, considered independently, represent a hydrogen atom, a linear or branched, saturated or unsaturated, if necessary substituted, C 1 to C 20 hydrocarbon radical possibly comprising one or more heteroatoms, or, when considered together with the carbon atoms to which they are bonded, can form aromatic or aliphatic monocyclic, bicyclic or tricyclic compounds, the radicals R 3 , R 4 and R 4 ′ possibly comprising functional groups of the ester and carbamoyl type so as to liberate several molecules of odoriferous alcohol R 1 OH per single molecule of precursor, are new compounds capable of liberating an odoriferous alcohol of the formula R 1 OH upon hydrolysis of the ester bond.

  化学式1所表示的化合物中，虚线表示单键或双键的位置；R1代表从具有化学式R1OH的芳香醇中衍生的基团；R2代表氢原子，线性或支链的饱和或不饱和的C1-C30烃基，或具有5或6个碳原子的脂环或芳环化合物，该基团R2可能包含氧、硫或氮等杂原子；符号R3、R4和R4'分别独立地表示氢原子，线性或支链的饱和或不饱和的，必要时取代的C1到C20烃基，可能包含一个或多个杂原子，或者与它们结合的碳原子一起形成芳香或脂环的单环、双环或三环化合物，基团R3、R4和R4'可能包含酯和氨基甲酸酯类型的官能团，以便每个前体分子释放数分子芳香醇R1OH，这些化合物是能够在酯键水解时释放化学式R1OH的芳香醇的新化合物。