7-Methoxy-3-(4-nitrophenyl)chromen-2-imine | 1277101-38-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 7-Methoxy-3-(4-nitrophenyl)chromen-2-imine
• CAS: 1277101-38-8
• 化学式: C₁₆H₁₂N₂O₄
• 分子量: 296.282
• InChiKey: TYHYBNXFXIHHRO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  22
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  88.1
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  7-Methoxy-3-(4-nitrophenyl)chromen-2-imine 在 吡啶 、 溶剂黄146 作用下， 以 氯仿 、 1,2-二氯乙烷 为溶剂， 反应 16.5h， 生成 1-[[7-methoxy-3-(4-nitrophenyl)chromen-2-ylidene]amino]-3-phenylimidazolidine-2,4,5-trione
  参考文献：
  名称：

  Synthesis of New Iminocoumarins Bearing Parabanic Moieties

  摘要：

  [image omitted] The synthesis of novel substituted 3-p-nitro-phenyliminocoumarins and corresponding N-ureaiminocoumarins is described. The condensation of these materials with oxalyl chloride leads to the corresponding N-parabanic iminocoumarins, which have not previously been described, in moderate or good yields and high selectivity. The structures were characterized by Fourier transform infrared, 1H and 13C NMR, and elemental analysis.

  DOI：

  10.1080/00397911003710562
• 作为产物：
  描述：

  2-羟基-4-甲氧基苯甲醛 、 对硝基苯乙腈 在 Amberlite IRA 900 resin 作用下， 以 甲苯 为溶剂， 反应 9.0h， 以75%的产率得到7-Methoxy-3-(4-nitrophenyl)chromen-2-imine
  参考文献：
  名称：

  Synthesis of New Iminocoumarins Bearing Parabanic Moieties

  摘要：

  [image omitted] The synthesis of novel substituted 3-p-nitro-phenyliminocoumarins and corresponding N-ureaiminocoumarins is described. The condensation of these materials with oxalyl chloride leads to the corresponding N-parabanic iminocoumarins, which have not previously been described, in moderate or good yields and high selectivity. The structures were characterized by Fourier transform infrared, 1H and 13C NMR, and elemental analysis.

  DOI：

  10.1080/00397911003710562

文献信息

• Synthesis of New Iminocoumarins Bearing Parabanic Moieties
  作者：Leila Benmaktouf、Houcine Ammar、Yves Le Bigot、Souhir Abid

  DOI：10.1080/00397911003710562

  日期：2011.3.3

  [image omitted] The synthesis of novel substituted 3-p-nitro-phenyliminocoumarins and corresponding N-ureaiminocoumarins is described. The condensation of these materials with oxalyl chloride leads to the corresponding N-parabanic iminocoumarins, which have not previously been described, in moderate or good yields and high selectivity. The structures were characterized by Fourier transform infrared, 1H and 13C NMR, and elemental analysis.