N-甲基-N-(5-甲基-3-异恶唑基)-乙酰胺 | 55809-21-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 亚胺内酰胺
• 中文名称: N-甲基-N-(5-甲基-3-异恶唑基)-乙酰胺
• 英文名称: N-methyl-N-(5-methyl-isoxazol-3-yl)-acetamide
• 英文别名: N-methyl-N-(5-methyl-1,2-oxazol-3-yl)acetamide
• CAS: 55809-21-7
• 化学式: C₇H₁₀N₂O₂
• 分子量: 154.169
• InChiKey: KAKUIYPUMWAHPI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  46.3
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• AGENT FOR IMPROVEMENT IN BOUNCE/BODY OF HAIR, AND HAIR COSMETIC
  申请人：Shiseido Company, Limited

  公开号：EP1911750A1

  公开（公告）日：2008-04-16

  A hair resiliency and body improver comprising as the active ingredient thereof one or more types of compounds selected from the group consisting of 2-aminothiazole derivatives represented by the following general formula (1) or 3-aminoisoxazole derivatives represented by the following general formula (2), and pharmaceutically acceptable salts thereof: (wherein, R1, R2, R3, R4, n and m are as defined in the description).

  一种头发弹性和发质改善剂，其活性成分包括一种或多种选自由下通式 (1) 所代表的 2-氨基噻唑衍生物或自由下通式 (2) 所代表的 3-氨基异恶唑衍生物组成的组的化合物及其药学上可接受的盐类： (其中，R1、R2、R3、R4、n 和 m 如说明中所定义）。
• Hair resiliency / body improver and hair cosmetic
  申请人：Shiseido Company, Limited

  公开号：EP2484342A1

  公开（公告）日：2012-08-08

  A hair resiliency and body improver comprising as the active ingredient thereof one or more types of compounds selected from the group consisting of 2-aminothiazole derivatives represented by the following general formula (1) or 3-aminoisoxazole derivatives represented by the following general formula (2), and pharmaceutically acceptable salts thereof: (wherein, R1, R2, R3, R4, n and m are as defined in the description).

  一种头发弹性和发质改善剂，其活性成分包括一种或多种选自由下通式 (1) 所代表的 2-氨基噻唑衍生物或自由下通式 (2) 所代表的 3-氨基异恶唑衍生物组成的组的化合物及其药学上可接受的盐类： (其中，R1、R2、R3、R4、n 和 m 如说明中所定义）。
• PHOSPHODIESTERASE 4 INHIBITORS
  申请人：Memory Pharmaceuticals Corporation

  公开号：EP1802615A1

  公开（公告）日：2007-07-04
• Hair resiliency/body improver and hair cosmetic
  申请人：Suetsugu Masaru

  公开号：US20090233975A1

  公开（公告）日：2009-09-17

  A hair resiliency and body improver comprising as the active ingredient thereof one or more types of compounds selected from the group consisting of 2-aminothiazole derivatives represented by the following general formula (1) or 3-aminoisoxazole derivatives represented by the following general formula (2), and pharmaceutically acceptable salts thereof: (wherein, R 1 , R 2 , R 3 , R 4 , n and m are as defined in the description).
• [EN] PHOSPHODIESTERASE 4 INHIBITORS<br/>[FR] INHIBITEURS DE LA PHOSPHODIÉSTÉRASE 4
  申请人：MEMORY PHARM CORP

  公开号：WO2006044955A1

  公开（公告）日：2006-04-27

  [EN] Selective PDE4 inhibition is achieved by novel compounds, e.g., 4-(substituted-phenyl)-2-pyrrolidinone compounds. The compounds of the present invention are of formula (I) wherein R[FR] L'inhibition sélective de la PDE4 peut être obtenue à l'aide de nouveaux composés, par exemple les dérivés de 2-pyrrolidinone portant en position 4 un groupement phényle substitué. Les composés décrits dans la présente invention répondent à la formule (I) où R