(2S,3S,5R)-3-[(tert-butyl-dimethylsilyl)oxy]-5-(2,4-dioxo-3H-pyrimidin-1-yl)oxolane-2-carbaldehyde | 139887-97-1

分子结构分类

有机化合物 - 有机杂环化合物 - 二嗪类

中文名称

——

中文别名

——

英文名称

(2S,3S,5R)-3-[(tert-butyl-dimethylsilyl)oxy]-5-(2,4-dioxo-3H-pyrimidin-1-yl)oxolane-2-carbaldehyde

英文别名

(2S,3S,5R)-3-[tert-butyl(dimethyl)silyl]oxy-5-(2,4-dioxopyrimidin-1-yl)oxolane-2-carbaldehyde

(2S,3S,5R)-3-[(tert-butyl-dimethylsilyl)oxy]-5-(2,4-dioxo-3H-pyrimidin-1-yl)oxolane-2-carbaldehyde化学式

CAS

139887-97-1

化学式

C₁₅H₂₄N₂O₅Si

mdl

——

分子量

340.451

InChiKey

PKHHNQZFUQYHHY-DMDPSCGWSA-N

BEILSTEIN

——

EINECS

——

物化性质

密度：

1.18±0.1 g/cm3(Predicted)

计算性质

辛醇/水分配系数(LogP)：

1.41
重原子数：

23.0
可旋转键数：

4.0
环数：

2.0
sp3杂化的碳原子比例：

0.67
拓扑面积：

90.39
氢给体数：

1.0
氢受体数：

6.0

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	3'-O-(tert-butyldimethylsilyl)-2'-deoxyuridine	76223-05-7	C₁₅H₂₆N₂O₅Si	342.467
——	3',5'-O-di(tert-butyldimethylsilyl)-2'-deoxyuridine	64911-18-8	C₂₁H₄₀N₂O₅Si₂	456.73
——	5'-O-benzoyl-3'-O-tert-butyldimethylsilyloxy-2'-deoxyuridine	139888-25-8	C₂₂H₃₀N₂O₆Si	446.575
——	1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-tetrahydrofuran-2-yl]pyrimidine-2,4-dione	113051-53-9	C₃₆H₄₄N₂O₇Si	644.84
2-脱氧尿苷	2'-Deoxyuridine	951-78-0	C₉H₁₂N₂O₅	228.205
——	5'-O-Benzoyl-2'-desoxy-β-D-ribofuranosyluracil	123606-62-2	C₁₆H₁₆N₂O₆	332.313
保护-2'-脱氧尿苷	DMT-dU	23669-79-6	C₃₀H₃₀N₂O₇	530.577

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	Uridine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-4'-formyl-	139888-02-1	C₁₆H₂₆N₂O₆Si	370.478
——	2'-deoxy-3'-O-t-butyldimethylsilyl-4'-hydroxymethyluridine	139888-00-9	C₁₆H₂₈N₂O₆Si	372.494
——	dimethyl {2-[(2R,5R)-3-[(tert-butyldimethylsilyl)oxy]-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]ethyl}phosphonate	1619230-22-6	C₁₈H₃₃N₂O₇PSi	448.528
——	1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]uracil	1363739-49-4	C₂₀H₃₇N₂O₇PSi	476.582
——	dimethyl [(E)-2-[(2R,5R)-3-[(tert-butyldimethylsilyl)oxy]-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)oxolan-2-yl]ethenyl]phosphonate	1619230-21-5	C₁₈H₃₁N₂O₇PSi	446.513
——	1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hex-5-enofuranosyl]uracil	1363739-44-9	C₂₀H₃₅N₂O₇PSi	474.566
——	2'-deoxy-3'-O-t-butyldimethylsilyl-4'-cyano-5'-O-acetyluridine	139888-08-7	C₁₈H₂₇N₃O₆Si	409.514
——	1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-bromouracil	1363739-50-7	C₂₀H₃₆BrN₂O₇PSi	555.478
——	1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-phenyluracil	1363739-51-8	C₂₆H₄₁N₂O₇PSi	552.68
——	{2-[(2S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]ethyl}phosphonic acid	1363739-83-6	C₁₀H₁₅N₂O₇P	306.212
——	{2‐[(2R,5R)‐5‐(2,4‐dioxo‐1,2,3,4‐tetrahydropyrimidin‐1‐yl)‐3‐hydroxyoxolan‐2‐yl]ethyl}phosphonic acid	1363739-81-4	C₁₀H₁₅N₂O₇P	306.212
——	4'-Cyano-2'-deoxyuridine	139888-12-3	C₁₀H₁₁N₃O₅	253.214
——	1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-(4-fluorophenyl)uracil	1363739-56-3	C₂₆H₄₀FN₂O₇PSi	570.67
——	1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-(naphthalen-1-yl)uracil	1363739-53-0	C₃₀H₄₃N₂O₇PSi	602.74
——	1-[2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]uracil	1363739-79-0	C₁₄H₂₃N₂O₇P	362.32
——	1-[3-O-tert-butyldimethylsilyl-2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-(thiophen-2-yl)uracil	1363739-58-5	C₂₄H₃₉N₂O₇PSSi	558.708
——	2'-deoxy-4'-cyano-5'-O-acetyluridine	139888-10-1	C₁₂H₁₃N₃O₆	295.252
——	Acetic acid (2R,3S,5R)-2-acetoxymethyl-2-cyano-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester	139888-14-5	C₁₄H₁₅N₃O₇	337.289
——	1-[2,5,6-trideoxy-6-(dihydroxyphosphinyl)-α-D-hexofuranosyl]-5-phenyluracil	1363739-68-7	C₁₆H₁₉N₂O₇P	382.31
——	1-[2,5,6-trideoxy-6-(dihydroxyphosphinyl)-β-D-hexofuranosyl]-5-phenyluracil	1363739-66-5	C₁₆H₁₉N₂O₇P	382.31
——	1-[2,5,6-trideoxy-6-(dihydroxyphosphinyl)-α-D-hexofuranosyl]-5-(4-fluorophenyl)uracil	1363739-76-7	C₁₆H₁₈FN₂O₇P	400.3
——	1-[2,5,6-trideoxy-6-(dihydroxyphosphinyl)-β-D-hexofuranosyl]-5-(4-fluorophenyl)uracil	1363739-73-4	C₁₆H₁₈FN₂O₇P	400.3
——	1-[2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-phenyluracil	1363739-59-6	C₂₀H₂₇N₂O₇P	438.417
——	1-[2,5,6-trideoxy-6-(dihydroxyphosphinyl)-α-D-hexofuranosyl]-5-(naphtalen-1-yl)uracil	1363739-71-2	C₂₀H₂₁N₂O₇P	432.37
——	1-[2,5,6-trideoxy-6-(dihydroxyphosphinyl)-β-D-hexofuranosyl]-5-(naphtalen-1-yl)uracil	1363739-69-8	C₂₀H₂₁N₂O₇P	432.37
——	1-[2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-(4-fluorophenyl)uracil	1363739-61-0	C₂₀H₂₆FN₂O₇P	456.408
——	1-[2,5,6-trideoxy-6-(dihydroxyphosphinyl)-α-D-hexofuranosyl]-5-(thiophen-2-yl)uracil	127235-80-7	C₁₄H₁₇N₂O₇PS	388.338
——	1-[2,5,6-trideoxy-6-(dihydroxyphosphinyl)-β-D-hexofuranosyl]-5-(thiophen-2-yl)uracil	127235-81-8	C₁₄H₁₇N₂O₇PS	388.338
——	4'-Cyano-2'-deoxycytidine	139888-13-4	C₁₀H₁₂N₄O₄	252.23
——	1-[2,5,6-trideoxy-6-(diethoxyphosphinyl)-β-D-hexofuranosyl]-5-(naphthalen-1-yl)uracil	1363739-60-9	C₂₄H₂₉N₂O₇P	488.477