phytanyl heptaethylene glycol succinate | 423763-18-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: phytanyl heptaethylene glycol succinate
• 英文别名: 4-O-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl] 1-O-[(7R,11R)-3,7,11,15-tetramethylhexadecyl] butanedioate
• CAS: 423763-18-2
• 化学式: C₃₈H₇₄O₁₁
• 分子量: 706.999
• InChiKey: KRHXPDMRASZHGD-CLDIWPSMSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  49
• 可旋转键数：
  40
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  128
• 氢给体数：
  1
• 氢受体数：
  11

反应信息

• 作为反应物：
  描述：

  丁二酸酐 、 phytanyl heptaethylene glycol succinate 以 吡啶 为溶剂， 反应 40.0h， 以96%的产率得到(phytanyl heptaethylene glycol succinate) hemisuccinate
  参考文献：
  名称：

  摘要：

  In order to optimize the performance of the AMBRI(TM) biosensor (Nature 1997, 387, 580), a variety of hydrophilic linkers between the hydrophobic bilayer membrane and the gold surface have been synthesized. The principal components are prepared from phytanyl hemisuccinate, which is linked by repeating ethylene glycol or propylene glycol units to a second succinic acid unit. The syntheses of analogous substances in which the ester links are replaced by amide and by ether links are also described.

  DOI：

  10.1071/ch01111
• 作为产物：
  描述：

  苄基-七聚乙二醇-四氢吡喃醚 在 palladium on activated charcoal 盐酸 、 4-二甲氨基吡啶 、 Morpho-CDI 、 氢气 作用下， 以 甲醇 、 乙醇 、 二氯甲烷 为溶剂， 反应 82.0h， 生成 phytanyl heptaethylene glycol succinate
  参考文献：
  名称：

  摘要：

  In order to optimize the performance of the AMBRI(TM) biosensor (Nature 1997, 387, 580), a variety of hydrophilic linkers between the hydrophobic bilayer membrane and the gold surface have been synthesized. The principal components are prepared from phytanyl hemisuccinate, which is linked by repeating ethylene glycol or propylene glycol units to a second succinic acid unit. The syntheses of analogous substances in which the ester links are replaced by amide and by ether links are also described.

  DOI：

  10.1071/ch01111