4-硝基苯基-β-L-吡喃阿拉伯糖苷 | 72732-54-8

• 物质功能分类: 生物化工 - 糖类化合物 - 单糖
• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 4-硝基苯基-β-L-吡喃阿拉伯糖苷
• 中文别名: 4-硝基苯基-Β-L-吡喃阿拉伯糖苷
• 英文名称: p-nitrophenyl-β-L-arabinopyranoside
• 英文别名: 4-Nitrophenyl beta-L-arabinopyranoside；(2R,3R,4S,5S)-2-(4-nitrophenoxy)oxane-3,4,5-triol
• CAS: 72732-54-8
• 化学式: C₁₁H₁₃NO₇
• mdl: MFCD00069787
• 分子量: 271.227
• InChiKey: MLJYKRYCCUGBBV-UKKRHICBSA-N

物化性质

• 熔点：
  183℃
• 沸点：
  523.2±50.0 °C(Predicted)
• 密度：
  1.597±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.454
• 拓扑面积：
  125
• 氢给体数：
  3
• 氢受体数：
  7

安全信息

• WGK Germany：
  3

反应信息

• 作为反应物：
  描述：

  4-硝基苯基-β-L-吡喃阿拉伯糖苷 在 甲醇 、 钯 作用下， 生成 (4-amino-phenyl)-β-L-arabinopyranoside
  参考文献：
  名称：

  Feier; Westphal, Chemische Berichte, 1956, vol. 89, p. 589,593

  摘要：

  DOI：
• 作为产物：
  描述：

  (4-nitro-phenyl)-(tri-O-acetyl-β-L-arabinopyranoside) 在 甲醇 、 sodium methylate 作用下， 生成 4-硝基苯基-β-L-吡喃阿拉伯糖苷
  参考文献：
  名称：

  Feier; Westphal, Chemische Berichte, 1956, vol. 89, p. 589,593

  摘要：

  DOI：

文献信息

• Formation of LacNAc mimetics employing novel donor substrates for enzymatic β1→4 galactosylation
  作者：Saskia Weingarten、Joachim Thiem

  DOI：10.1039/b400916a

  日期：——

  In examining C-6 modified 4-nitrophenyl β-D-galactopyranosides as donor structures the β-galactosidase (Bacillus circulans) revealed an unexpectedly broad substrate specificity which allowed successful syntheses of various disaccharide components.

  在研究作为供体结构的 C-6 修饰的 4-硝基苯基 δ-D-吡喃半乳糖苷时，δ-半乳糖苷酶（环状芽孢杆菌）显示出出人意料的广泛底物特异性，从而成功合成了各种双糖成分。
• THERMOSTABLE BETA-XYLOSIDASE
  申请人：HONDA MOTOR CO., LTD.

  公开号：US20160168548A1

  公开（公告）日：2016-06-16

  A thermostable β-xylosidase, having a β-xylosidase catalytic domain including: (A) a polypeptide including the amino acid sequence represented by SEQ ID NO: 1 or 2, (B) a polypeptide including an amino acid sequence in which at least one amino acid has been deleted, substituted, or added in the amino acid sequence represented by SEQ ID NO: 1 or 2, and having hydrolysis activity against a substrate of p-nitrophenyl-β-D-xylopyranoside at least under conditions of 105° C. and pH 5.0, or (C) a polypeptide including an amino acid sequence having 75% or greater sequence identity with the amino acid sequence represented by SEQ ID NO: 1 or 2, and having hydrolysis activity against a substrate of p-nitrophenyl-β-D-xylopyranoside at least under conditions of 105° C. and pH 5.0.

  一种具有热稳定性的β-木糖苷酶，包括β-木糖苷酶催化域，其中：（A）包括由SEQ ID NO:1或2表示的氨基酸序列的多肽，（B）包括在SEQ ID NO:1或2表示的氨基酸序列中删除、替换或添加至少一个氨基酸的氨基酸序列的多肽，并且在105°C和pH 5.0条件下对p-硝基苯基-β-D-木糖吡喃糖基底物具有水解活性，或（C）包括与SEQ ID NO:1或2表示的氨基酸序列具有75％或更高的序列同源性的氨基酸序列的多肽，并且在105°C和pH 5.0条件下对p-硝基苯基-β-D-木糖吡喃糖基底物具有水解活性。
• THERMOSTABLE BETA-XYLOSIDASE BELONGING TO GH FAMILY 3
  申请人：HONDA MOTOR CO., LTD.

  公开号：US20160032265A1

  公开（公告）日：2016-02-04

  A thermostable β-xylosidase including a β-xylosidase catalytic domain, the β-xylosidase catalytic domain including: (A) a polypeptide including an amino acid sequence represented by SEQ ID NO: 1; (B) a polypeptide including an amino acid sequence in which at least one amino acid is deleted, substituted, or added in the amino acid sequence represented by SEQ ID NO: 1, and having hydrolytic activity using p-nitrophenyl-β-D-xylopyranoside as a substrate at least under conditions of a temperature of 85° C. and a pH of 6.0; or (C) a polypeptide including an amino acid sequence having at least 80% sequence identity with the amino acid sequence represented by SEQ ID NO: 1, and having hydrolytic activity using p-nitrophenyl-β-D-xylopyranoside as a substrate at least under conditions of a temperature of 85° C. and a pH of 6.0.

  一种热稳定的β-木糖苷酶，包括β-木糖苷酶催化结构域，该β-木糖苷酶催化结构域包括：（A）一个多肽，包括由SEQ ID NO: 1表示的氨基酸序列；（B）一个多肽，包括在SEQ ID NO: 1表示的氨基酸序列中至少删除、替换或添加一个氨基酸，并在至少85°C和pH 6.0的条件下使用对硝基苯基-β-D-木糖苷作为底物具有水解活性；或（C）一个多肽，包括至少80％序列同源性与由SEQ ID NO: 1表示的氨基酸序列相同，并在至少85°C和pH 6.0的条件下使用对硝基苯基-β-D-木糖苷作为底物具有水解活性。
• HYPERTHERMOSTABLE ENDOGLUCANASE BELONGING TO GH FAMILY 12
  申请人：HONDA MOTOR CO., LTD.

  公开号：US20160122791A1

  公开（公告）日：2016-05-05

  A hyperthermostable endoglucanase including an endoglucanase catalytic domain, the endoglucanase catalytic domain including: (A) a polypeptide including an amino acid sequence represented by SEQ ID NO: 1; (B) a polypeptide including an amino acid sequence in which at least one amino acid is deleted, substituted, or added in the amino acid sequence represented by SEQ ID NO: 1, and having hydrolytic activity using p-nitrophenyl-β-D-cellobioside as a substrate at least under conditions of a temperature of 100° C. and a pH of 5.5; or (C) a polypeptide including an amino acid sequence having at least 70% sequence identity with the amino acid sequence represented by SEQ ID NO: 1, and having hydrolytic activity using p-nitrophenyl-β-D-cellobioside as a substrate at least under conditions of a temperature of 100° C. and a pH of 5.5.

  一种高温稳定的内切葡聚糖酶，包括一个内切葡聚糖酶催化结构域，该内切葡聚糖酶催化结构域包括：（A）一个多肽，包括由SEQ ID NO: 1表示的氨基酸序列；（B）一个多肽，包括在由SEQ ID NO: 1表示的氨基酸序列中至少删除、替换或添加一个氨基酸，并在至少100℃和pH 5.5的条件下使用对硝基苯基-β-D-纤维二糖为底物具有水解活性；或（C）一个多肽，包括与由SEQ ID NO: 1表示的氨基酸序列具有至少70%的序列同源性的氨基酸序列，并在至少100℃和pH 5.5的条件下使用对硝基苯基-β-D-纤维二糖为底物具有水解活性。
• THERMOSTABLE XYLANASE BELONGING TO GH FAMILY 10
  申请人：HONDA MOTOR CO., LTD.

  公开号：EP2980210A1

  公开（公告）日：2016-02-03

  A thermostable xylanase including a xylanase catalytic domain, the xylanase catalytic domain including: (A) a polypeptide comprising an amino acid sequence represented by SEQ ID NO:1; (B) a polypeptide including an amino acid sequence in which at least one amino acid is deleted, substituted, or added in the amino acid sequence represented by SEQ ID NO: 1, and having xylanase activity at least under conditions of a temperature of 90°C and a pH of 6.0; or (C) a polypeptide including an amino acid sequence having at least 75% sequence identity with the amino acid sequence represented by SEQ ID NO: 1, and having xylanase activity at least under conditions of a temperature of 90°C and a pH of 6.0.

  一种包括木聚糖酶催化结构域的可恒温木聚糖酶，该木聚糖酶催化结构域包括 (A) 包含由 SEQ ID NO:1 所代表的氨基酸序列的多肽； (B) 包括氨基酸序列的多肽，其中至少一个氨基酸在 SEQ ID NO:1 所代表的氨基酸序列中被删除、取代或添加，并且至少在温度为 90°C 和 pH 为 6.0 的条件下具有木聚糖酶活性；或 (C) 包括与 SEQ ID NO: 1 所代表的氨基酸序列具有至少 75% 序列同一性的氨基酸序列的多肽，且至少在温度为 90°C 和 pH 为 6.0 的条件下具有木聚糖酶活性。