1,9-Dihydroxy-3-methoxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 1,9-Dihydroxy-3-methoxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one
• 化学式: C₂₁H₁₈O₆
• 分子量: 366.4
• InChiKey: PVKQULHHWVQXLE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  27
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  89.1
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  溴甲苯 、 1,9-Dihydroxy-3-methoxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one 生成 glycyrol dibenzyl ether
  参考文献：
  名称：

  SHIOZAWA, TATSUSHI;URATA, SHIGEO;KINOSHITA, TAKESHI;SAITOH, TAMOTSU, CHEM. AND PHARM. BULL., 37,(1989) N, C. 2239-2240

  摘要：

  DOI：

文献信息

• COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES
  申请人：Johansen Lisa M.

  公开号：US20100009970A1

  公开（公告）日：2010-01-14

  The present invention features compositions, methods, and kits useful in the treatment of viral diseases. In certain embodiments, the viral disease is caused by a single stranded RNA virus, a flaviviridae virus, or a hepatic virus. In particular embodiments, the viral disease is viral hepatitis (e.g., hepatitis A, hepatitis B, hepatitis C, hepatitis D, hepatitis E) and the agent or combination of agents includes sertraline, a sertraline analog, UK-416244, or a UK-416244 analog. Also featured are screening methods for identification of novel compounds that may be used to treat a viral disease.

  本发明涉及用于治疗病毒性疾病的组合物、方法和试剂盒。在某些实施方式中，病毒性疾病是由单链RNA病毒、黄病毒科病毒或肝病毒引起的。在特定实施方式中，病毒性疾病是病毒性肝炎（例如甲型肝炎、乙型肝炎、丙型肝炎、丁型肝炎、戊型肝炎），药剂或药剂组合包括舍曲林、舍曲林类似物、UK-416244或UK-416244类似物。还包括用于鉴定可用于治疗病毒性疾病的新化合物的筛选方法。
• COMPOSITION CONTAINING LICORICE-DERIVED POLYPHENOL
  申请人：Kaneka Corporation

  公开号：EP2163252A1

  公开（公告）日：2010-03-17

  A composition containing a licorice polyphenol and other active ingredient (antioxidant ingredient, polyphenol other than licorice polyphenol or a component relating to lipid absorption or metabolism) is highly safe, can be produced easily, and can be utilized for foods and drinks such as health food, food with health claims (specified health food, food with nutrient function claims) and the like, pharmaceutical products, quasi-drugs, cosmetics and the like. In addition, since the composition has a body fat accumulation suppressing effect, a body fat decomposition promoting effect or energy production promoting effect, it is useful for the treatment of obesity, metabolic syndrome and the like.

  含有甘草多酚和其他活性成分（抗氧化成分、甘草多酚以外的多酚或与脂质吸收或代谢有关的成分）的组合物安全性高，易于生产，可用于保健食品、健康声称食品（指定保健食品、营养功能声称食品）等食品和饮料、医药产品、准药品、化妆品等。此外，由于该组合物具有抑制体内脂肪堆积的效果、促进体内脂肪分解的效果或促进能量产生的效果，因此可用于治疗肥胖症、代谢综合征等。
• METHOD OF PRODUCING REDUCED COENZYME Q10 AND METHOD OF STABILIZING THE SAME
  申请人：Kaneka Corporation

  公开号：EP2186789A1

  公开（公告）日：2010-05-19

  The present invention provides a stabilization method of reduced coenzyme Q10 useful as food, food with nutrient function claims, food for specified health uses, nutritional supplement, nutritional supplement, animal drugs, drinks, feeds, cosmetics, pharmaceutical products, therapeutic drugs, prophylactic drugs and the like, as well as a stabilized composition. Furthermore, it provides a convenient production method of reduced coenzyme Q10 using oxidized coenzyme Q10 as a starting material. In the present invention, oxidation of reduced coenzyme Q10 can be suppressed, and reduced coenzyme Q10 can be stably maintained by the co-presence of a licorice hydrophobic extract and reduced coenzyme Q10. In addition, reduced coenzyme Q10 can be produced by the co-presence of oxidized coenzyme Q10 and a licorice hydrophobic extract.

  本发明提供了一种还原型辅酶 Q10 的稳定化方法，可用于食品、声称具有营养功能的食品、特定保健用途食品、营养补充剂、营养补充品、动物药品、饮料、饲料、化妆品、医药产品、治疗药物、预防药物等，以及稳定化组合物。此外，本发明还提供了一种以氧化辅酶 Q10 为起始原料的还原型辅酶 Q10 的便捷生产方法。在本发明中，通过甘草疏水提取物和还原型辅酶Q10的共存，可以抑制还原型辅酶Q10的氧化，并稳定地维持还原型辅酶Q10。此外，氧化型辅酶 Q10 和甘草疏水提取物共存可产生还原型辅酶 Q10。
• RESIN COMPOSITION FOT THROUGH-HOLE FILLING.
  申请人：AJINOMOTO CO., INC.

  公开号：EP3819324A1

  公开（公告）日：2021-05-12

  Provided are a resin composition and so forth that can enhance a desmear resistance and an adhesion property between a magnetic layer and a conductive layer and that can give a cured product having a swelling of the conductive layer after a reflow treatment suppressed. The resin composition includes (A) a magnetic powder, (B-1) a solid resin, (B-2) a liquid resin, and (C) a curing accelerator having a melting point of 120°C or higher and 245°C or lower, in which b1/b2 is in the range of 0.15 or more and 0.45 or less, where b1 is a content of the (B-1) component when non-volatile components in the resin composition is taken as 100% by mass, and b2 is a content of the (B-2) component when non-volatile components in the resin composition is taken as 100% by mass.

  本发明提供了一种树脂组合物等，它能增强磁性层和导电层之间的抗剥离性和粘合性，并能得到回流处理后导电层膨胀受到抑制的固化产品。该树脂组合物包括 (A) 磁粉、(B-1) 固体树脂、(B-2) 液体树脂和 (C) 固化促进剂，其熔点为 120°C 或以上和 245°C 或以下，其中 b1/b2 的范围为 0.15 或以上和 0.45 或更低，其中 b1 是（B-1）组分的含量，当树脂组合物中的非挥发性组分的质量百分比为 100%时；b2 是（B-2）组分的含量，当树脂组合物中的非挥发性组分的质量百分比为 100%时。
• RESIN COMPOSITION
  申请人：AJINOMOTO CO., INC.

  公开号：EP3859757A1

  公开（公告）日：2021-08-04

  Provided is a resin composition including (A) a ferrite and (B) a thermosetting resin, in which a carbon amount included in the (A) component is 0.1% or less by mass relative to 100% by mass of the (A) component, a relative permeability (10 MHz) of a cured product obtained by thermally curing the resin composition at 180°C for 90 minutes is 8 or more, and a maximum point strength (23°C) of a cured product obtained by thermally curing the resin composition at 190°C for 90 minutes is 40 MPa or more.

  本发明提供了一种树脂组合物，包括（A）铁氧体和（B）热固性树脂，其中（A）组份中包含的碳量相对于（A）组份 100%的质量为 0.1% 或更少（以质量计），通过在 180°C 下热固化树脂组合物 90 分钟而获得的固化产品的相对渗透率（10 MHz）为 8 或更高，通过在 190°C 下热固化树脂组合物 90 分钟而获得的固化产品的最大点强度（23°C）为 40 兆帕或更高。