3.4-seco-5β-cholestanedioic acid-(3.4) | 1177-97-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 3.4-seco-5β-cholestanedioic acid-(3.4)
• 英文别名: 3.4-Seco-5β-cholestandisaeure-(3.4)；3,4-Seco-5β-cholestandisaeure-(3,4)；(3R,3aR,5aS,6R,7S,9aS,9bS)-6-(2-carboxyethyl)-3a,6-dimethyl-3-[(2R)-6-methylheptan-2-yl]-2,3,4,5,5a,7,8,9,9a,9b-decahydro-1H-cyclopenta[a]naphthalene-7-carboxylic acid
• CAS: 1177-97-5
• 化学式: C₂₇H₄₆O₄
• 分子量: 434.66
• InChiKey: CUKZMECJGGZUMT-HBDZIZKSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  31
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3.4-seco-5β-cholestanedioic acid-(3.4) 在 乙酸酐 作用下， 生成 A-nor-5β-cholestan-3-one
  参考文献：
  名称：

  Auditory Model Enhances Relative-Timing Learning

  摘要：

  In recent experiments (Q. Lai, C. H. Shea, & M. Little, 2000; C. H. Shea, G. Wulf, J. Park, & B. Gaunt, 2001), auditory models were found to be effective in enhancing relative-timing performance and learning in constant practice conditions. In the present experiment, the authors examined (a) whether an auditory model also enhances relative-timing learning in blocked and random practice conditions and (b) whether experience with the auditory model enhances participants' ability to produce the response by using different effector sequences. Participants (N = 48) were randomly assigned to 1 of 4 acquisition conditions in which an auditory model was or was not present and the practice schedule was blocked or random. In the acquisition phase, all participants alternately pressed 2 keys on a keyboard in an attempt to match 5 goal intervals. In the auditory model conditions, a sequence of tones was played before each acquisition trial. The tones represented the correct timing sequence for that trial. One retention and 3 effector-transfer tests without feedback were administered about 24 hr after the completion of acquisition. The results indicated that the auditory model enhanced relative-timing performance and learning independently of practice schedule. In addition, the auditory model enhanced relative timing on the effector-transfer tests, but absolute-timing performance and learning were not affected by the auditory model. Thus, relative timing was found to be effector independent but absolute timing was not.

  DOI：

  10.1080/00222890209601948
• 作为产物：
  描述：

  cholesterol 在 chromium(VI) oxide 、 镍 、 溶剂黄146 作用下， 生成 3.4-seco-5β-cholestanedioic acid-(3.4)
  参考文献：
  名称：

  Langer, Hoppe-Seyler's Zeitschrift fur Physiologische Chemie, 1933, vol. 216, p. 189,191

  摘要：

  DOI：

文献信息

• Hydroxy-steroids. Part XI. The preparation and infrared spectra of vicinal cholestanediols
  作者：C. W. Davey、E. L. McGinnis、J. M. McKeown (née Chancellor)、G. D. Meakins、M. W. Pemberton、R. N. Young

  DOI：10.1039/j39680002674

  日期：——

  Twenty-eight vicinal cholestanediols (positions 1,2; 2,3; 3,4; 4,5; 5,6; 6,7; and 7,8) have been prepared by unambiguous routes starting from the corresponding olefins. The O–H stretching bands of dilute solutions of these diols and of seven reference compounds have been examined under high dispersion. Characteristic differences between ax,ax, ax,eq, and eq,eq compounds were observed. It was concluded

  已经通过从相应的烯烃开始的明确途径制备了二十八个邻位胆固醇二醇（1,2,2,3; 3,4; 4,5; 5,6; 6,7和7,8位）。这些二醇和七种参考化合物的稀溶液的O–H伸缩带已在高分散度下进行了检测。观察到ax，ax，ax，eq和eq，eq化合物之间的特性差异。结论是，不能通过游离和键合羟基的吸收之间的频率差来获得羟基之间的二面角的精确值。
• The Set of Poles of a Two-Sheeted Hyperboloid
  作者：Robert Sinclair、Minoru Tanaka

  DOI：10.1080/10586458.2002.10504466

  日期：2002.1

  It has been conjectured for some time that the set of poles of a rotationally symmetric two-sheeted hyperboloid breaks into two disjoint sets if symmetry is broken by contraction perpendicular to the original axis of symmetry. We provide the first reliable visualizations of this process, confirming previous conjectures and motivating new ones.
• Full-Scale Evaluation of Mercury Control with Sorbent Injection and COHPAC at Alabama Power E.C. Gaston
  作者：C. Jean Bustard、Michael Durham、Charles Lindsey、Travis Starns、Ken Baldrey、Cameron Martin、Richard Schlager、Sharon Sjostrom、Rick Slye、Scott Renninger、Larry Monroe、Richard Miller、Ramsay Chang

  DOI：10.1080/10473289.2002.10470832

  日期：2002.8

  The overall objective of this project was to determine the cost and impacts of leg control using sorbent injection into a Compact Hybrid Particulate Collector (COHPAC) at Alabama Power's Gaston Unit 3. This test is part of a program funded by the U.S. Department of Energy's National Energy Technology Laboratory (NETL) to obtain the necessary information to assess the costs of controlling Hg from coal-fired utility plants that do not have scrubbers for SO2 control. The economics will be developed based on various levels of Hg control.Gaston Unit 3 was chosen for testing because COHPAC represents a cost-effective retrofit option for utilities with existing electrostatic precipitators (ESPs). COHPAC is an EPRI-patented concept that places a high air-to-cloth ratio baghouse downstream of an existing ESP to improve overall particulate collection efficiency. Activated carbons were injected upstream of COHPAC and downstream of the ESP to obtain performance and operational data.Results were very encouraging, with up to 90% removal of Hg for short operating periods using powdered activated carbon (PAC). During the long-term tests, an average Hg removal efficiency of 78% was measured. The PAC injection rate for the long-term tests was chosen to maintain COHPAC cleaning frequency at less than 1.5 pulses/bag/hr.
• Über Gallensäuren und verwandte Stoffe. 17. Mitteilung. Bildung von Lactonen aus Ketonen mit Benzopersäure
  作者：V. Burckhardt、T. Reichstein

  DOI：10.1002/hlca.19420250704

  日期：1942.12.1
• Sur les constituants de l'ambre gris II. Ambréine et Coprostanone
  作者：E. Lederer、F. Marx、D. Mercier、G. Pérot

  DOI：10.1002/hlca.19460290563

  日期：——