N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-methoxybenzenesulfonamide | 159005-71-7

分子结构分类

有机化合物 - 苯类化合物 - 苯和取代衍生物

中文名称

——

中文别名

——

英文名称

N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-methoxybenzenesulfonamide

英文别名

N-[(2R,3S)-3-amino-2-hydroxy-4-phenylbutyl]-4-methoxy-N-(2-methylpropyl)benzenesulfonamide

N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-methoxybenzenesulfonamide化学式

CAS

159005-71-7

化学式

C₂₁H₃₀N₂O₄S

mdl

——

分子量

406.546

InChiKey

IMIQIWQBJKROCN-LEWJYISDSA-N

BEILSTEIN

——

EINECS

——

物化性质

沸点：

585.5±60.0 °C(Predicted)
密度：

1.192±0.06 g/cm3(Predicted)

计算性质

辛醇/水分配系数(LogP)：

2.8
重原子数：

28
可旋转键数：

10
环数：

2.0
sp3杂化的碳原子比例：

0.43
拓扑面积：

101
氢给体数：

2
氢受体数：

6

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	N-[(2R,3S)-3-azido-2-hydroxy-4-phenylbutyl]-N-isobutyl-4-methoxybenzenesulfonamide	253265-96-2	C₂₁H₂₈N₄O₄S	432.544
——	tert-butyl (1S,2R)-1-benzyl-2-hydroxy-3-{isobutyl[(4-methoxyphenyl)sulfonyl]amino}propylcarbamate	159006-03-8	C₂₆H₃₈N₂O₆S	506.664
——	N-((2R,3S)-3-(dibenzylamino)-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-methoxybenzenesulfonamide	799241-79-5	C₃₅H₄₂N₂O₄S	586.795
——	Phenylmethyl [2R-hydroxy-3-[(2-methylpropyl)(4-methoxyphenylsulfonyl)amino]-1S-(phenylmethyl)propyl]carbamate	157566-99-9	C₂₉H₃₆N₂O₆S	540.681

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	(3R)-3-hydroxy-N-[(1S,2R)-2-hydroxy-3-[[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)propyl]-pentamide	918294-82-3	C₂₆H₃₈N₂O₆S	506.664
——	2-morpholinoethyl ((2S,3R)-3-hydroxy-4-(N-isobutyl-4-methoxyphenylsulfonamido)-1-phenylbutan-2-yl)carbamate	——	C₂₈H₄₁N₃O₇S	563.715
——	(2S)-2-(acetylamino)-N-[(1S,2R)-2-hydroxy-3-[[(4-methoxyphenyl)sulfonyl][2-methylpropyl]amino]-1-(phenylmethyl)propyl]-propanamide	918295-06-4	C₂₆H₃₇N₃O₆S	519.662
——	N-[(1S,2R)-2-hydroxy-3-[[(4-methoxyphenyl)sulfonyl][2-methylpropyl]amino]-1-(phenylmethyl)propyl]-3-methyl-4,4,4-trifluoro-2-butenamide	918295-05-3	C₂₆H₃₃F₃N₂O₅S	542.62
——	N-{(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-propyl}-benzamide	——	C₂₈H₃₄N₂O₅S	510.654
1-环丙烷-N-[(1S,2R)-2-羟基-3-[[(4-甲氧基苯基)磺酰基](2-甲基丙基)氨基]-1-(苯基甲基)丙基]-1,1-二甲酰胺	1-cyclopropane-N-[(1S,2R)-2-hydroxy-3-[[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)propyl]-1,1-dicarboxamide	1026701-10-9	C₂₆H₃₅N₃O₆S	517.646
——	N-{(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-propyl}-2-(2,6-dimethyl-phenoxy)-acetamide	——	C₃₁H₄₀N₂O₆S	568.734
——	N-{(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-propyl}-isonicotinamide	——	C₂₇H₃₃N₃O₅S	511.642
——	(1S,2R)-{1-benzyl-2-hydroxy-3-[isobutyl(4-methoxybenzenesulfonyl)amino]propyl}carbamic acid cycloheptanyl ester	1067244-23-8	C₂₉H₄₂N₂O₆S	546.728
——	(1S,2R)-{1-benzyl-2-hydroxy-3-[isobutyl(4-methoxybenzenesulfonyl)amino]propyl}carbamic acid 1,3-dioxan-5-yl ester	1067244-24-9	C₂₆H₃₆N₂O₈S	536.646
——	N-{(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-propyl}-4-methyl-benzamide	——	C₂₉H₃₆N₂O₅S	524.681
——	(1S,2R)-{1-benzyl-2-hydroxy-3-[isobutyl(4-methoxybenzenesulfonyl)amino]propyl}carbamic acid 3,6,9-trioxacyclodecan-1-yl ester	1067244-25-0	C₂₉H₄₂N₂O₉S	594.726
——	(1S,2R)-{1-benzyl-2-hydroxy-3-[isobutyl(4-methoxybenzenesulfonyl)amino]propyl}carbamic acid 3,6,9,12-tetraoxacyclotridecan-1-yl ester	1067244-26-1	C₃₁H₄₆N₂O₁₀S	638.78
——	N-((1S,2R)-1-Benzyl-2-hydroxy-3-{isobutyl[(4-methoxyphenyl)sulfonyl]amino}propyl)-3-methylbenzamide	——	C₂₉H₃₆N₂O₅S	524.681
——	(1S,2R)-{1-benzyl-2-hydroxy-3-[isobutyl(4-methoxybenzenesulfonyl)amino]propyl}carbamic acid 3,6,8,11-tetraoxacyclododecan-1-yl ester	1067244-27-2	C₃₀H₄₄N₂O₁₀S	624.753
——	N-[(2R,3S)-3-(diethoxyphosphorylamino)-2-hydroxy-4-phenyl-butyl]-N-isobutyl-4-methoxy-benzenesulfonamide	1402829-89-3	C₂₅H₃₉N₂O₇PS	542.634
——	3-hydroxy-N-[(1S,2R)-2-hydroxy-3-[[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)propyl]-benzamide	——	C₂₈H₃₄N₂O₆S	526.654
——	{(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-(4-methoxy-benzenesulfonyl)-amino]-propyl}-carbamic acid (S)-(tetrahydro-thiophen-3-yl) ester	——	C₂₆H₃₆N₂O₆S₂	536.714
——	(1S,2R)-{1-benzyl-2-hydroxy-3-[isobutyl(4-methoxybenzenesulfonyl)amino]propyl}carbamic acid (S)-oxepan-4-yl ester	1067244-22-7	C₂₈H₄₀N₂O₇S	548.701
——	N-[(1S,2R)-1-benzyl-2-hydroxy-3-[isobutyl-(4-methoxyphenyl)sulfonyl-amino]propyl]-3-methoxy-benzamide	——	C₂₉H₃₆N₂O₆S	540.681