(3R,5S)-3-benzyl-5-{(1S)-1-[(tert-butoxycarbonyl)amino]-2-phenylethyl}dihydrofuran-2-(3H)-one | 98818-41-8

分子结构分类

有机化合物 - 苯类化合物 - 苯和取代衍生物

中文名称

——

中文别名

——

英文名称

(3R,5S)-3-benzyl-5-{(1S)-1-[(tert-butoxycarbonyl)amino]-2-phenylethyl}dihydrofuran-2-(3H)-one

英文别名

(3R, 5S, 1-S)-3-Benzyl-5-(1-((1,1-dimethylethoxycarbonyl)amino)-2-phenylethyl)dihydrofuran-2-(3H)-one；5(S)-[1(S)-(Boc-amino)-2-phenylethyl]-3(R)-phenylmethyl-dihydrofuran-2-(3H)-one；5(S)-[1(S)-(Boc-Amino)-2-phenylethyl]-3(R)-phenylmethyldihydrofuran-2-(3H)-one；5(S)-[1(S)-(Boc-amino)-2-phenylethyl]-3(R)-phenylmethyldihydrofuran-2-(3H)one；tert-butyl N-[(1S)-1-[(2S,4R)-4-benzyl-5-oxooxolan-2-yl]-2-phenylethyl]carbamate

(3R,5S)-3-benzyl-5-{(1S)-1-[(tert-butoxycarbonyl)amino]-2-phenylethyl}dihydrofuran-2-(3H)-one化学式

CAS

98818-41-8

化学式

C₂₄H₂₉NO₄

mdl

——

分子量

395.499

InChiKey

APKWYHZUGMVPDD-HKBOAZHASA-N

BEILSTEIN

——

EINECS

——

物化性质

熔点：

75-77 °C
沸点：

579.1±33.0 °C(Predicted)
密度：

1.143±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

辛醇/水分配系数(LogP)：

5
重原子数：

29
可旋转键数：

8
环数：

3.0
sp3杂化的碳原子比例：

0.42
拓扑面积：

64.6
氢给体数：

1
氢受体数：

4

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	(3R,5R)-3-benzyl-5-{(1S)-1-[(tert-butoxycarbonyl)amino]-2-phenylethyl}dihydrofuran-2-(3H)-one	98737-42-9	C₂₄H₂₉NO₄	395.499
——	(4S,5S)-5-<1-(t-Boc-amino)-2-phenylethyl>-3-(phenylmethyl)dihydrofuran-2(3H)-one	——	C₂₄H₂₉NO₄	395.499
——	(3S,5S)-3-benzyl-5-{(1S)-1-[(tert-butoxycarbonyl)amino]-2-phenylethyl}dihydrofuran-2-(3H)-one	98818-42-9	C₂₄H₂₉NO₄	395.499
——	tert-butyl (1S)-1-[(2S)-5-oxotetrahydrofuran-2-yl]-2-phenylethylcarbamate	133333-27-4	C₁₇H₂₃NO₄	305.374
——	(5S,1'S)-carbetoxy-5-<1-<<(1',1-dimethylothoxy)carbonyl>amino>-2-phenylmethyl>dihydrofuran-2(3H)-one	193338-94-2	C₂₀H₂₇NO₆	377.437
——	(3R,5S,1'S)-3-Benzyl-5-<1'--2'-phenylethyl>dihydrofuran-2(3H)-one	145655-08-9	C₃₁H₃₅NO₄	485.623
——	(2R,4R,5S)-2-Benzyl-5-(tert-butoxycarbonyl)amino-4-hydroxy-6-phenylhexanoic acid	98818-43-0	C₂₄H₃₁NO₅	413.514
——	5(S)-(Boc-amino)-4(S)-hydroxy-6-phenyl-2(R)-phenylmethylhexanoic acid	98818-45-2	C₂₄H₃₁NO₅	413.514
——	(3R,5R)-3-benzyl-5-[(1S)-1-(dibenzylamino)-2-phenylethyl]oxolan-2-one	190521-32-5	C₃₃H₃₃NO₂	475.631
——	(5S,1'S)-5-<1'--2'-phenylethyl>dihydrofuran-2(3H)-one	145655-07-8	C₂₄H₂₉NO₄	395.499
——	5(S)-(Boc-amino)-4(S)-hydroxy-6-phenyl-hexanoic acid ethyl ester	135103-86-5	C₁₉H₂₉NO₅	351.443
——	tert-butyl (4S,5S)-4-benzyl-5-(3-ethoxy-3-oxopropyl)-2,2-dimethyl-1,3-oxazolidine-3-carboxylate	742109-02-0	C₂₂H₃₃NO₅	391.508
——	[(3S,4S)-4-[(2-methylpropan-2-yl)oxycarbonylamino]-5-phenylpent-1-en-3-yl] prop-2-enoate	210294-28-3	C₁₉H₂₅NO₄	331.412
——	tert-butyl N-[(1S)-1-[(2S)-5-oxo-2H-furan-2-yl]-2-phenylethyl]carbamate	210294-29-4	C₁₇H₂₁NO₄	303.358
——	(4S,5S)-2,2-dimethyl-3-(tert-butoxycarbonyl)-4-benzyl-5-formyl-1,3-oxazolidine	134458-64-3	C₁₈H₂₅NO₄	319.401
——	3-O-tert-butyl 5-O-methyl (4S,5R)-4-benzyl-2,2-dimethyl-1,3-oxazolidine-3,5-dicarboxylate	203806-77-3	C₁₉H₂₇NO₅	349.427

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	(3S,5S)-3-benzyl-5-{(1S)-1-[(tert-butoxycarbonyl)amino]-2-phenylethyl}dihydrofuran-2-(3H)-one	98818-42-9	C₂₄H₂₉NO₄	395.499
——	5(S)-(Boc-amino)-4(S)-hydroxy-6-phenyl-2(R)-phenylmethylhexanoic acid	98818-45-2	C₂₄H₃₁NO₅	413.514
——	(2S,4S,5S)-2-benzyl-4-hydroxy-5-[(2-methylpropan-2-yl)oxycarbonylamino]-6-phenylhexanoic acid	98818-44-1	C₂₄H₃₁NO₅	413.514
——	N-(1,1-dimethylethoxycarbonyl)-5(S)-amino-4(S)-(t-butyldimethylsilyloxy)-6-phenyl-2(R)-(phenylmethyl)hexanoic acid	98818-51-0	C₃₀H₄₅NO₅Si	527.777
——	(2S,4S,5S)-5-{[(1,1-dimethylethoxy)carbonyl]amino}-4-{[(1,1-dimethylethyl)dimethylsilyl]oxy}-6-phenyl-2-(phenylmethyl)hexanoic acid	98818-50-9	C₃₀H₄₅NO₅Si	527.777
——	tert-butyl N-[(1S,2S,4R)-1,4-dibenzyl-2-hydroxy-5-(isopentylamino)-5-oxo-pentyl]carbamate	132565-32-3	C₂₉H₄₂N₂O₄	482.663
——	(2R,4S,5S)-N,2-dibenzyl-5-[(tert-butoxycarbonyl)amino]-4-hydroxy-6-phenylhexanamide	126409-25-4	C₃₁H₃₈N₂O₄	502.654
——	[(1S,2S,4R)-1-Benzyl-4-((S)-1-carbamoyl-3-methyl-butylcarbamoyl)-2-hydroxy-5-phenyl-pentyl]-carbamic acid tert-butyl ester	126409-30-1	C₃₀H₄₃N₃O₅	525.689
——	[(1S,2S,4R)-1-Benzyl-2-hydroxy-4-((S)-3-methyl-1-phenethylcarbamoyl-butylcarbamoyl)-5-phenyl-pentyl]-carbamic acid tert-butyl ester	132565-31-2	C₃₈H₅₁N₃O₅	629.84
——	{(1S,2S,4R)-1-Benzyl-4-[(S)-1-(2,3-dihydroxy-propylcarbamoyl)-2-methyl-butylcarbamoyl]-2-hydroxy-5-phenyl-pentyl}-carbamic acid tert-butyl ester	126409-66-3	C₃₃H₄₉N₃O₇	599.768
——	((1S,2S,4S)-4-amino-1-benzyl-2-hydroxy-5-phenyl-pentyl)-carbamic acid tert-butyl ester	144163-88-2	C₂₃H₃₂N₂O₃	384.519
N-{(2R,4S,5S)-2-苯甲基-5-[(叔-丁氧基羰基)氨基]-4-羟基-6-苯基己酰}-L-亮氨酰-L-苯丙氨酸酰胺	{(1S)-benzyl-(4R)-[1-((1S)-carbamoyl-2-phenyl-ethylcarbamoyl)-(1S)-3-methyl-butyl-carbamoyl]-(2S)-hydroxy-5-phenyl-pentyl} carbamic acid tert-butyl ester	126409-24-3	C₃₉H₅₂N₄O₆	672.865
(5S)-(叔丁氧羰基氨基)-6-苯基-(4R)-羟基-(2R)-苄基己酰)-L-亮氨酰-L-苯丙氨酰胺	(5S)-(tert-butoxycarbonylamino)-6-phenyl-(4R)-hydroxy-(2R)-benzylhexanoyl-L-leucy-L-phenylalaninamide	292632-98-5	C₃₉H₅₂N₄O₆	672.865
——	Carbamic acid, (2-hydroxy-5-((3-methyl-1-(((phenylmethyl)amino)carbonyl)butyl)amino)-5-oxo-1,4-bis(phenylmethyl)pentyl)-, 1,1-dimethylethyl ester, (1S-(1R,2R,4S,5(R)))-	98818-68-9	C₃₇H₄₉N₃O₅	615.813
——	[(1S,2S,4R)-1-Benzyl-4-((S)-1-benzylcarbamoyl-2-methyl-butylcarbamoyl)-2-hydroxy-5-phenyl-pentyl]-carbamic acid tert-butyl ester	——	C₃₇H₄₉N₃O₅	615.813
——	(2S,4S,5S)-2,5-bis<<(1,1-dimethylethoxy)carbonyl>amino>-1,6-diphenyl-4-hydroxyhexane	144141-82-2	C₂₈H₄₀N₂O₅	484.636
——	(2S,4R,5S)-2,5-bis<<(1,1-dimethylethoxy)carbonyl>amino>-1,6-diphenyl-4-hydroxyhexane	——	C₂₈H₄₀N₂O₅	484.636
——	(2S,4S,5S)-2-<<(phenylmethoxy)carbonyl>amino>-5-<<(1,1-dimethylethoxy)carbonyl>amino>-1,6-diphenyl-4-hydroxyhexane	146500-09-6	C₃₁H₃₈N₂O₅	518.653
——	N'-(2-benzimidazolylmethyl)-N-<5(S)-<(tert-butoxycarbonyl)amino>-4(S)-hydroxy-6-phenyl-2(R)-(phenylmethyl)hexanoyl>isoleucine amide	126409-81-2	C₃₈H₄₉N₅O₅	655.838
叔-丁基[(1S,2S,4R)-1,4-二苯甲基-2-羟基-5-{[(1S,2R)-2-羟基-2,3-二氢-1H-茚-1-基]氨基}-5-羰基戊基]氨基甲酸酯	L-685434	126456-36-8	C₃₃H₄₀N₂O₅	544.691