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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (4,5-dimethylthiophen-2-yl)-[(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C20H25F3N4OS
    (4,5-dimethylthiophen-2-yl)-[(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— (4,5-dimethylthiophen-2-yl)-[(3R)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C20H25F3N4OS
    (4,5-dimethylthiophen-2-yl)-[(3R)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— [(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5-dimethylthiophen-2-yl)methanone —— C20H26F2N4OS
    [(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5-dimethylthiophen-2-yl)methanone
    —— 2-methyl-5-[(3R)-1-[(6-methyl-1,3-benzodioxol-5-yl)methyl]piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine —— C21H25N5O2
    2-methyl-5-[(3R)-1-[(6-methyl-1,3-benzodioxol-5-yl)methyl]piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
    —— 2-methyl-5-[(3S)-1-[(6-methyl-1,3-benzodioxol-5-yl)methyl]piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine —— C21H25N5O2
    2-methyl-5-[(3S)-1-[(6-methyl-1,3-benzodioxol-5-yl)methyl]piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
    —— [4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5-dimethylthiophen-2-yl)methanone —— C20H26F2N4OS
    [4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5-dimethylthiophen-2-yl)methanone
    —— [(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5-dimethylthiophen-2-yl)methanone —— C20H26F2N4OS
    [(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5-dimethylthiophen-2-yl)methanone
    —— [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2S)-2-(3-methyl-1,2-oxazol-5-yl)azepan-1-yl]methanone —— C21H23F2N5O2
    [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2S)-2-(3-methyl-1,2-oxazol-5-yl)azepan-1-yl]methanone
    —— [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2R)-2-(3-methyl-1,2-oxazol-5-yl)azepan-1-yl]methanone —— C21H23F2N5O2
    [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-[(2R)-2-(3-methyl-1,2-oxazol-5-yl)azepan-1-yl]methanone
    —— (4R)-1-[5,6-dimethyl-2-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-pyridin-3-ylazepan-4-ol —— C23H26N6O2
    (4R)-1-[5,6-dimethyl-2-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-pyridin-3-ylazepan-4-ol
    —— [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2R)-2-(3-methyl-1,2-oxazol-5-yl)azepan-1-yl]methanone —— C21H23F2N5O2
    [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2R)-2-(3-methyl-1,2-oxazol-5-yl)azepan-1-yl]methanone
    —— [5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2S)-2-(3-methyl-1,2-oxazol-5-yl)azepan-1-yl]methanone —— C21H22F3N5O2
    [5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2S)-2-(3-methyl-1,2-oxazol-5-yl)azepan-1-yl]methanone
    —— (3-methyl-1,2-oxazol-5-yl)-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H24F3N5O2
    (3-methyl-1,2-oxazol-5-yl)-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone —— C21H29F2N5O2
    [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone
    —— (3-methyl-1,2-oxazol-5-yl)-[(3S)-3-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C18H22F3N5O2
    (3-methyl-1,2-oxazol-5-yl)-[(3S)-3-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2R)-2-(3-methyl-1,2-oxazol-5-yl)azepan-1-yl]methanone —— C21H22F3N5O2
    [5-cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2R)-2-(3-methyl-1,2-oxazol-5-yl)azepan-1-yl]methanone
    —— [(3R)-3-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone —— C21H28F3N5O2
    [(3R)-3-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone
    —— [(2S)-2-[5-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone —— C21H24F3N5O2
    [(2S)-2-[5-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone
    —— (3-methyl-1,2-oxazol-5-yl)-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C17H20F3N5O2
    (3-methyl-1,2-oxazol-5-yl)-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone —— C18H23F2N5O2
    [(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone
    —— (4S)-1-[5,6-dimethyl-2-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-pyridin-3-ylazepan-4-ol —— C23H26N6O2
    (4S)-1-[5,6-dimethyl-2-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl]-4-pyridin-3-ylazepan-4-ol
    —— (3-methyl-1,2-oxazol-5-yl)-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C17H20F3N5O2
    (3-methyl-1,2-oxazol-5-yl)-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (3-methyl-1,2-oxazol-5-yl)-[(3R)-3-[(5R,7S)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C20H26F3N5O2
    (3-methyl-1,2-oxazol-5-yl)-[(3R)-3-[(5R,7S)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2S)-2-(3-methyl-1,2-oxazol-5-yl)azepan-1-yl]methanone —— C21H23F2N5O2
    [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2S)-2-(3-methyl-1,2-oxazol-5-yl)azepan-1-yl]methanone
    —— (3-methyl-1,2-oxazol-5-yl)-[(3R)-3-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C18H22F3N5O2
    (3-methyl-1,2-oxazol-5-yl)-[(3R)-3-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [(3R)-3-(4-methyl-6-thiophen-2-ylpyrimidin-2-yl)piperidin-1-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone —— C21H20N6OS
    [(3R)-3-(4-methyl-6-thiophen-2-ylpyrimidin-2-yl)piperidin-1-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone
    —— 5-methyl-2-[(2S)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C17H21F3N4O
    5-methyl-2-[(2S)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— [(3R)-3-(4-methyl-6-thiophen-2-ylpyrimidin-2-yl)piperidin-1-yl]-pyrazolo[1,5-a]pyrimidin-2-ylmethanone —— C21H20N6OS
    [(3R)-3-(4-methyl-6-thiophen-2-ylpyrimidin-2-yl)piperidin-1-yl]-pyrazolo[1,5-a]pyrimidin-2-ylmethanone
    —— [4-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone —— C21H28F3N5O2
    [4-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone
    —— [(3S)-3-(4-methyl-6-thiophen-2-ylpyrimidin-2-yl)piperidin-1-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone —— C21H20N6OS
    [(3S)-3-(4-methyl-6-thiophen-2-ylpyrimidin-2-yl)piperidin-1-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone
    —— 2-[(2R)-1-[(3-fluorophenyl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H18F4N4
    2-[(2R)-1-[(3-fluorophenyl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— [(2R)-2-[5-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone —— C21H24F3N5O2
    [(2R)-2-[5-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone
    —— 2-[(3R)-1-[(3-fluorophenyl)methyl]pyrrolidin-3-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H18F4N4
    2-[(3R)-1-[(3-fluorophenyl)methyl]pyrrolidin-3-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (3-methyl-1,2-oxazol-5-yl)-[(3R)-3-[(5R,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C20H26F3N5O2
    (3-methyl-1,2-oxazol-5-yl)-[(3R)-3-[(5R,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— (6-fluoro-1H-benzimidazol-2-yl)-[(3R)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H16F4N6O
    (6-fluoro-1H-benzimidazol-2-yl)-[(3R)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 2-[(3S)-1-[(2-fluorophenyl)methyl]pyrrolidin-3-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H18F4N4
    2-[(3S)-1-[(2-fluorophenyl)methyl]pyrrolidin-3-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(2R)-1-[(2-fluoro-4-methoxyphenyl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H20F4N4O
    2-[(2R)-1-[(2-fluoro-4-methoxyphenyl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-methyl-2-[(2R)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C17H21F3N4O
    5-methyl-2-[(2R)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(2R)-1-[(2-methoxyphenyl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H21F3N4O
    2-[(2R)-1-[(2-methoxyphenyl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— [(3S)-3-(4-methyl-6-thiophen-2-ylpyrimidin-2-yl)piperidin-1-yl]-pyrazolo[1,5-a]pyrimidin-2-ylmethanone —— C21H20N6OS
    [(3S)-3-(4-methyl-6-thiophen-2-ylpyrimidin-2-yl)piperidin-1-yl]-pyrazolo[1,5-a]pyrimidin-2-ylmethanone
    —— 2-[(3S)-1-[(4-fluorophenyl)methylsulfonyl]pyrrolidin-3-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H18F4N4O2S
    2-[(3S)-1-[(4-fluorophenyl)methylsulfonyl]pyrrolidin-3-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(2S)-1-[(5-tert-butyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H25F3N6
    2-[(2S)-1-[(5-tert-butyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-methyl-2-[(2S)-1-(thian-4-yl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C17H21F3N4S
    5-methyl-2-[(2S)-1-(thian-4-yl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5,7-dimethyl-N-(2-propan-2-yloxyethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide —— C14H20N4O2
    5,7-dimethyl-N-(2-propan-2-yloxyethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
    —— 2-methyl-4-[4-[[(3S)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methyl]phenyl]but-3-yn-2-ol —— C24H25F3N4O
    2-methyl-4-[4-[[(3S)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methyl]phenyl]but-3-yn-2-ol
    —— 2-methyl-4-[4-[[(3R)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methyl]phenyl]but-3-yn-2-ol —— C24H25F3N4O
    2-methyl-4-[4-[[(3R)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methyl]phenyl]but-3-yn-2-ol
    —— 2-[N-methyl-4-[[(2R)-2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methyl]anilino]ethanol —— C22H26F3N5O
    2-[N-methyl-4-[[(2R)-2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methyl]anilino]ethanol
    —— 2-[(2R)-1-[(5-tert-butyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H25F3N6
    2-[(2R)-1-[(5-tert-butyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (4-methylthiadiazol-5-yl)-[(2R)-2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C17H17F3N6OS
    (4-methylthiadiazol-5-yl)-[(2R)-2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 5,7-dimethyl-N-[(1R)-2-(6-oxo-2-propan-2-yl-1H-pyrimidin-4-yl)-1-phenylethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C24H26N6O2
    5,7-dimethyl-N-[(1R)-2-(6-oxo-2-propan-2-yl-1H-pyrimidin-4-yl)-1-phenylethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide