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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 5-amino-N-[4-(1-azabicyclo[2.2.2]octan-3-yloxy)pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H20FN7O2
    5-amino-N-[4-(1-azabicyclo[2.2.2]octan-3-yloxy)pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 5-amino-6-fluoro-N-[4-(1-methylpyrrolidin-3-yl)oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H18FN7O2
    5-amino-6-fluoro-N-[4-(1-methylpyrrolidin-3-yl)oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 5-amino-6-fluoro-N-[4-[4-(3-methoxypyrrolidine-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C23H27FN8O3
    5-amino-6-fluoro-N-[4-[4-(3-methoxypyrrolidine-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(2-fluoro-3-pyridin-4-yl-2H-pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H13F2N7O
    2-amino-6-fluoro-N-(2-fluoro-3-pyridin-4-yl-2H-pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-[1-[(2-methylphenyl)methyl]pyrazol-3-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C23H17F3N6OS
    N-[1-[(2-methylphenyl)methyl]pyrazol-3-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-piperidin-1-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-5-carboxamide —— C17H17F2N7O
    2-amino-6-fluoro-N-(5-fluoro-4-piperidin-1-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-5-carboxamide
    —— 2-amino-N-[6-[4-(azetidin-1-yl)piperidine-1-carbonyl]-3-pyridin-4-yl-2H-pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C26H28FN9O2
    2-amino-N-[6-[4-(azetidin-1-yl)piperidine-1-carbonyl]-3-pyridin-4-yl-2H-pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 5-amino-6-chloro-N-[4-(1-methylpyrrolidin-3-yl)oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H18ClN7O2
    5-amino-6-chloro-N-[4-(1-methylpyrrolidin-3-yl)oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 6-Fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C7H5FN4O
    6-Fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-butoxypyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H17FN6O2
    2-amino-N-(4-butoxypyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— (R)-2-amino-6-fluoro-N-(4-(4-(3-methoxypyrrolidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-83-0 C23H27FN8O3
    (R)-2-amino-6-fluoro-N-(4-(4-(3-methoxypyrrolidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-(1-cyanocycloprop-2-en-1-yl)-N-[5-fluoro-4-[4-[(4-methylpiperazin-1-yl)methyl]piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C27H31FN10O
    2-amino-6-(1-cyanocycloprop-2-en-1-yl)-N-[5-fluoro-4-[4-[(4-methylpiperazin-1-yl)methyl]piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-[1-(2-methylbenzyl)-1H-pyrazol-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H16N6O
    N-[1-(2-methylbenzyl)-1H-pyrazol-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— [(2R)-2-ethylpiperidin-1-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone —— C14H18N4O
    [(2R)-2-ethylpiperidin-1-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone
    —— [(2S)-2-ethylpiperidin-1-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone —— C14H18N4O
    [(2S)-2-ethylpiperidin-1-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone
    —— [(2R)-2-ethylpiperidin-1-yl]-[5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone —— C19H19F3N4O2
    [(2R)-2-ethylpiperidin-1-yl]-[5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone
    —— [(2S)-2-ethylpiperidin-1-yl]-[5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone —— C19H19F3N4O2
    [(2S)-2-ethylpiperidin-1-yl]-[5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone
    —— (5S,7R)-N-[3-(1H-imidazol-3-ium-3-yl)propyl]-5-phenyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H22F3N6O+
    (5S,7R)-N-[3-(1H-imidazol-3-ium-3-yl)propyl]-5-phenyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— (5R,7R)-N-[3-(1H-imidazol-3-ium-3-yl)propyl]-5-phenyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H22F3N6O+
    (5R,7R)-N-[3-(1H-imidazol-3-ium-3-yl)propyl]-5-phenyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— (5R,7S)-N-[3-(1H-imidazol-3-ium-3-yl)propyl]-5-phenyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H22F3N6O+
    (5R,7S)-N-[3-(1H-imidazol-3-ium-3-yl)propyl]-5-phenyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-{3,5-dimethyl-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-pyrazol-4-yl}-5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C23H22F3N7O3
    N-{3,5-dimethyl-1-[2-oxo-2-(pyrrolidin-1-yl)ethyl]-1H-pyrazol-4-yl}-5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 5-(2-furanyl)-N-[1-[(2-methylphenyl)methyl]-3-pyrazolyl]-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamide —— C23H17F3N6O2
    5-(2-furanyl)-N-[1-[(2-methylphenyl)methyl]-3-pyrazolyl]-7-(trifluoromethyl)-3-pyrazolo[1,5-a]pyrimidinecarboxamide
    —— Ethyl 4-{[5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}piperazine-1-carboxylate —— C19H18F3N5O4
    Ethyl 4-{[5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]carbonyl}piperazine-1-carboxylate
    —— Ethyl 4-carbamoyl-5-[({7-[chloro(difluoro)methyl]-5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-2-yl}carbonyl)amino]-3-methylthiophene-2-carboxylate —— C21H16ClF2N5O4S2
    Ethyl 4-carbamoyl-5-[({7-[chloro(difluoro)methyl]-5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidin-2-yl}carbonyl)amino]-3-methylthiophene-2-carboxylate
    —— N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H14F3N5O2S
    N-(3-cyano-4-ethyl-5-methylthiophen-2-yl)-5-(furan-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 3-{[4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl]carbonyl}pyrazolo[1,5-a]pyrimidine —— C19H19N5O3
    3-{[4-(1,3-Benzodioxol-5-ylmethyl)-1-piperazinyl]carbonyl}pyrazolo[1,5-a]pyrimidine
    —— [4-(1,3-Benzodioxol-5-ylmethyl)piperazin-4-ium-1-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone —— C19H20N5O3+
    [4-(1,3-Benzodioxol-5-ylmethyl)piperazin-4-ium-1-yl]-pyrazolo[1,5-a]pyrimidin-3-ylmethanone
    —— (4-Benzylpiperazin-4-ium-1-yl)-[7-[chloro(difluoro)methyl]-5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-2-yl]methanone —— C23H21ClF2N5OS+
    (4-Benzylpiperazin-4-ium-1-yl)-[7-[chloro(difluoro)methyl]-5-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-2-yl]methanone
    —— (2,2,2-Trifluoroacetyl) 1-[3-[(2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]-5-fluoropyridin-4-yl]piperidine-4-carboxylate —— C20H16F5N7O4
    (2,2,2-Trifluoroacetyl) 1-[3-[(2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]-5-fluoropyridin-4-yl]piperidine-4-carboxylate
    —— 7-[chloro(difluoro)methyl]-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide —— C21H14ClF2N5OS2
    7-[chloro(difluoro)methyl]-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
    —— 2-amino-6-fluoro-N-[4-[4-(2-methoxyethylsulfonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H24FN7O4S
    2-amino-6-fluoro-N-[4-[4-(2-methoxyethylsulfonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(5-chloro-4-pyrrolidin-1-ylpyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H15ClFN7O
    2-amino-N-(5-chloro-4-pyrrolidin-1-ylpyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-(4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-07-1 C22H28ClN9O
    2-amino-6-chloro-N-(4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(4-pyridazin-4-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H11FN8O
    2-amino-6-fluoro-N-(4-pyridazin-4-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-pyrrolidin-1-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H15F2N7O
    2-amino-6-fluoro-N-(5-fluoro-4-pyrrolidin-1-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 7-[chloro(difluoro)methyl]-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide —— C20H12ClF2N5OS2
    7-[chloro(difluoro)methyl]-N-(3-cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-5-(thiophen-2-yl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
    —— 2-amino-N-[5-chloro-4-(3-cyanopyrrolidin-1-yl)pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H14ClFN8O
    2-amino-N-[5-chloro-4-(3-cyanopyrrolidin-1-yl)pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-(1,1-dioxo-1,4-thiazinan-4-yl)-5-fluoropyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H15F2N7O3S
    2-amino-N-[4-(1,1-dioxo-1,4-thiazinan-4-yl)-5-fluoropyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 4-[3-[(2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]pyridin-4-yl]-N,N-dimethylmorpholine-2-carboxamide —— C19H21FN8O3
    4-[3-[(2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]pyridin-4-yl]-N,N-dimethylmorpholine-2-carboxamide
    —— 2-amino-N-[4-(1,1-dihydroxy-1,4-thiazinan-4-yl)-5-fluoropyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H17F2N7O3S
    2-amino-N-[4-(1,1-dihydroxy-1,4-thiazinan-4-yl)-5-fluoropyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-(1-cyanoethyl)-N-(4-methoxypyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H15N7O2
    2-amino-6-(1-cyanoethyl)-N-(4-methoxypyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-[3-(2-methoxyethyl)imidazol-4-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H17FN8O2
    2-amino-6-fluoro-N-[4-[3-(2-methoxyethyl)imidazol-4-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(oxetan-3-yloxy)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C15H13FN6O3
    2-amino-6-fluoro-N-[4-(oxetan-3-yloxy)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-(cyanomethyl)-N-(4-morpholin-4-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H18N8O2
    2-amino-6-(cyanomethyl)-N-(4-morpholin-4-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(3-methylpyrazol-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H13FN8O
    2-amino-6-fluoro-N-[4-(3-methylpyrazol-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[5-chloro-4-[(3R)-3-cyanopyrrolidin-1-yl]pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H14ClFN8O
    2-amino-N-[5-chloro-4-[(3R)-3-cyanopyrrolidin-1-yl]pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-(4-(4-(5,6-dihydroimidazo[1,5-a]pyrazin-7(8H)-yl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-11-7 C23H25ClN10O
    2-amino-6-chloro-N-(4-(4-(5,6-dihydroimidazo[1,5-a]pyrazin-7(8H)-yl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-(4-(4-(6-oxa-1-azaspiro[3.3]heptan-1-yl)piperidin-1-yl)pyridin-3-yl)-2-amino-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-19-5 C22H25ClN8O2
    N-(4-(4-(6-oxa-1-azaspiro[3.3]heptan-1-yl)piperidin-1-yl)pyridin-3-yl)-2-amino-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-(4-((1-methylpiperidin-4-yl)carbamoyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-29-4 C24H29F2N9O2
    2-amino-6-fluoro-N-(5-fluoro-4-(4-((1-methylpiperidin-4-yl)carbamoyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-(4-(4-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-25-0 C23H24F2N8O3
    N-(4-(4-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide