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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-amino-6-chloro-N-[4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H22ClN7O2
    2-amino-6-chloro-N-[4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-(4-(4-cyclobutylpiperazine-1-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-39-6 C26H31F2N9O2
    2-amino-N-(4-(4-(4-cyclobutylpiperazine-1-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(2-methylimidazol-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H13FN8O
    2-amino-6-fluoro-N-[4-(2-methylimidazol-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-(4-(4-([1,4'-bipiperidine]-1'-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-57-8 C28H35F2N9O2
    N-(4-(4-([1,4'-bipiperidine]-1'-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-[4-(trifluoromethyl)imidazol-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H10F4N8O
    2-amino-6-fluoro-N-[4-[4-(trifluoromethyl)imidazol-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-(4-pyrrolidin-3-yloxypyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H16ClN7O2
    2-amino-6-chloro-N-(4-pyrrolidin-3-yloxypyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-[4-(6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H16ClN9O
    2-amino-6-chloro-N-[4-(6,8-dihydro-5H-imidazo[1,5-a]pyrazin-7-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(pyrrolidin-1-yl)piperidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-56-7 C27H33F2N9O2
    2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-(pyrrolidin-1-yl)piperidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-[(3S)-1-(oxetan-3-yl)piperidin-3-yl]oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H22FN7O3
    2-amino-6-fluoro-N-[4-[(3S)-1-(oxetan-3-yl)piperidin-3-yl]oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(1-methyl-2-oxopiperidin-4-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H18FN7O2
    2-amino-6-fluoro-N-[4-(1-methyl-2-oxopiperidin-4-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-[4-(3-methoxypyrrolidine-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C23H27FN8O3
    2-amino-6-fluoro-N-[4-[4-(3-methoxypyrrolidine-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(4-(4-(3-fluoroazetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-72-7 C21H22F2N8O2
    2-amino-6-fluoro-N-(4-(4-(3-fluoroazetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-(4-(4-(3-methoxypyrrolidin-1-yl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-05-9 C22H27ClN8O2
    2-amino-6-chloro-N-(4-(4-(3-methoxypyrrolidin-1-yl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-(4-(8-methyl-3,8-diazabicyclo[3.2.1]octane-3-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-51-2 C25H29F2N9O2
    2-amino-6-fluoro-N-(5-fluoro-4-(4-(8-methyl-3,8-diazabicyclo[3.2.1]octane-3-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[1-(1-methylpiperidine-4-carbonyl)-3,6-dihydro-2H-pyridin-4-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C24H26F2N8O2
    2-amino-6-fluoro-N-[5-fluoro-4-[1-(1-methylpiperidine-4-carbonyl)-3,6-dihydro-2H-pyridin-4-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-(4-(4-([1,3'-biazetidine]-1'-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-49-8 C24H27F2N9O2
    N-(4-(4-([1,3'-biazetidine]-1'-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-(4-imidazol-1-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C15H11ClN8O
    2-amino-6-chloro-N-(4-imidazol-1-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-(cyanomethyl)-N-(4-piperidin-1-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H20N8O
    2-amino-6-(cyanomethyl)-N-(4-piperidin-1-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-[4-(4-cyclopropylpiperazine-1-carbonyl)piperidin-1-yl]-5-fluoropyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C25H29F2N9O2
    2-amino-N-[4-[4-(4-cyclopropylpiperazine-1-carbonyl)piperidin-1-yl]-5-fluoropyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-[4-[(3S,4S)-4-(dimethylamino)-3-hydroxypiperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H23ClN8O2
    2-amino-6-chloro-N-[4-[(3S,4S)-4-(dimethylamino)-3-hydroxypiperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-(4-(4-(2-oxa-6-azaspiro[3.4]octan-6-yl)piperidin-1-yl)pyridin-3-yl)-2-amino-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-09-3 C23H27ClN8O2
    N-(4-(4-(2-oxa-6-azaspiro[3.4]octan-6-yl)piperidin-1-yl)pyridin-3-yl)-2-amino-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-(4,5-dimethylimidazol-1-yl)pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H15FN8O
    2-amino-N-[4-(4,5-dimethylimidazol-1-yl)pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— Methyl 1-[3-[(2-amino-6-chloropyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]pyridin-4-yl]piperidine-4-carboxylate —— C19H20ClN7O3
    Methyl 1-[3-[(2-amino-6-chloropyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]pyridin-4-yl]piperidine-4-carboxylate
    —— 2-amino-N-(4-(4-((2-(azetidin-1-yl)ethyl)carbamoyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-45-4 C23H27F2N9O2
    2-amino-N-(4-(4-((2-(azetidin-1-yl)ethyl)carbamoyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(4-methyl-4-methylsulfonylpiperidin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H22FN7O3S
    2-amino-6-fluoro-N-[4-(4-methyl-4-methylsulfonylpiperidin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-(4-(3-(methylsulfonyl)azetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-76-1 C22H24F2N8O4S
    2-amino-6-fluoro-N-(5-fluoro-4-(4-(3-(methylsulfonyl)azetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[4-[(2-oxopyrrolidin-1-yl)methyl]piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C22H24F2N8O2
    2-amino-6-fluoro-N-[5-fluoro-4-[4-[(2-oxopyrrolidin-1-yl)methyl]piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-(cyanomethyl)-N-(4-pyrrolidin-3-yloxypyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H18N8O2
    2-amino-6-(cyanomethyl)-N-(4-pyrrolidin-3-yloxypyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-(1-azaspiro[3.3]heptan-6-yloxy)pyridin-3-yl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H18ClN7O2
    2-amino-N-[4-(1-azaspiro[3.3]heptan-6-yloxy)pyridin-3-yl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-(4-(dimethylcarbamoyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-35-2 C20H22F2N8O2
    2-amino-N-(4-(4-(dimethylcarbamoyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-methyl-4,7-diazaspiro[2.5]octane-7-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-42-1 C25H29F2N9O2
    2-amino-6-fluoro-N-(5-fluoro-4-(4-(4-methyl-4,7-diazaspiro[2.5]octane-7-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(4-(4-(3-(methylsulfonyl)azetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-79-4 C22H25FN8O4S
    2-amino-6-fluoro-N-(4-(4-(3-(methylsulfonyl)azetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-(1-azabicyclo[2.2.2]octan-3-yloxy)pyridin-3-yl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H20ClN7O2
    2-amino-N-[4-(1-azabicyclo[2.2.2]octan-3-yloxy)pyridin-3-yl]-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-[4-[3-(dimethylamino)pyrrolidine-1-carbonyl]piperidin-1-yl]-5-fluoropyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C24H29F2N9O2
    2-amino-N-[4-[4-[3-(dimethylamino)pyrrolidine-1-carbonyl]piperidin-1-yl]-5-fluoropyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-(cyanomethyl)-N-(4-piperidin-4-yloxypyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H20N8O2
    2-amino-6-(cyanomethyl)-N-(4-piperidin-4-yloxypyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— US11370798, Cmpd. # I-O-44 —— C17H17FN6O3S
    US11370798, Cmpd. # I-O-44
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[4-(1,3-thiazol-2-yl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H18F2N8OS
    2-amino-6-fluoro-N-[5-fluoro-4-[4-(1,3-thiazol-2-yl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-(4-(4-(3-(dimethylamino)pyrrolidin-1-yl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-16-2 C23H30ClN9O
    2-amino-6-chloro-N-(4-(4-(3-(dimethylamino)pyrrolidin-1-yl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-[4-(1-methylpyrrolidin-3-yl)oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H18ClN7O2
    2-amino-6-chloro-N-[4-(1-methylpyrrolidin-3-yl)oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— (S)-2-amino-N-(4-(4-(3,4-dimethylpiperazine-1-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-48-7 C24H29F2N9O2
    (S)-2-amino-N-(4-(4-(3,4-dimethylpiperazine-1-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— (R)-2-amino-N-(4-(4-(3-(dimethylamino)pyrrolidine-1-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-24-9 C24H29F2N9O2
    (R)-2-amino-N-(4-(4-(3-(dimethylamino)pyrrolidine-1-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(4-piperidin-1-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H18FN7O
    2-amino-6-fluoro-N-(4-piperidin-1-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(5-methylimidazol-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H13FN8O
    2-amino-6-fluoro-N-[4-(5-methylimidazol-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-[4-[(3aR,7aR)-2-methyl-3-oxo-1,3a,4,6,7,7a-hexahydropyrrolo[3,4-c]pyridin-5-yl]pyridin-3-yl]-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H21FN8O2
    N-[4-[(3aR,7aR)-2-methyl-3-oxo-1,3a,4,6,7,7a-hexahydropyrrolo[3,4-c]pyridin-5-yl]pyridin-3-yl]-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[4-(1-methylpyrrolidin-3-yl)oxypiperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C22H26F2N8O2
    2-amino-6-fluoro-N-[5-fluoro-4-[4-(1-methylpyrrolidin-3-yl)oxypiperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-(4-(octahydropyrrolo[3,4-c]pyrrole-2-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-97-6 C24H27F2N9O2
    2-amino-6-fluoro-N-(5-fluoro-4-(4-(octahydropyrrolo[3,4-c]pyrrole-2-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-[4-[(3,3-difluoropyrrolidin-1-yl)methyl]piperidin-1-yl]pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C22H25F3N8O
    2-amino-N-[4-[4-[(3,3-difluoropyrrolidin-1-yl)methyl]piperidin-1-yl]pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(4-methylsulfonylpiperidin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H20FN7O3S
    2-amino-6-fluoro-N-[4-(4-methylsulfonylpiperidin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-[4-(oxolan-3-yloxy)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H15ClN6O3
    2-amino-6-chloro-N-[4-(oxolan-3-yloxy)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-(1,1-dihydroxythian-4-yl)oxypyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H19FN6O4S
    2-amino-N-[4-(1,1-dihydroxythian-4-yl)oxypyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide