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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methyl-2-(4-methylphenoxy)propan-1-one —— C24H32F2N4O2
    1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methyl-2-(4-methylphenoxy)propan-1-one
    —— 4-methyl-N-[(1S)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-phenylethyl]-1,2,5-oxadiazole-3-carboxamide —— C19H18N6O3
    4-methyl-N-[(1S)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-phenylethyl]-1,2,5-oxadiazole-3-carboxamide
    —— 2-(2-methoxy-4-methylphenoxy)-1-[(2R)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]ethanone —— C22H26N4O3
    2-(2-methoxy-4-methylphenoxy)-1-[(2R)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]ethanone
    —— (2R)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2,4-dimethylphenoxy)propan-1-one —— C24H32F2N4O2
    (2R)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2,4-dimethylphenoxy)propan-1-one
    —— 7-[(3R)-1-benzylpyrrolidin-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine —— C18H20N4
    7-[(3R)-1-benzylpyrrolidin-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine
    —— 4-(2-fluorophenoxy)-1-[(2R)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]butan-1-one —— C22H25FN4O2
    4-(2-fluorophenoxy)-1-[(2R)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]butan-1-one
    —— (5R,7R)-2-[(2S)-1-[(2-methoxy-5-methylphenyl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C21H27F3N4O
    (5R,7R)-2-[(2S)-1-[(2-methoxy-5-methylphenyl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— 7-[(2S)-1-[1-(difluoromethyl)-5-methylpyrazol-4-yl]sulfonylpyrrolidin-2-yl]-2-methylpyrazolo[1,5-a]pyrimidine —— C16H18F2N6O2S
    7-[(2S)-1-[1-(difluoromethyl)-5-methylpyrazol-4-yl]sulfonylpyrrolidin-2-yl]-2-methylpyrazolo[1,5-a]pyrimidine
    —— (2S)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2,4-dimethylphenoxy)propan-1-one —— C24H32F2N4O2
    (2S)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2,4-dimethylphenoxy)propan-1-one
    —— [(2S)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-pyrazin-2-ylmethanone —— C17H18N6O
    [(2S)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-pyrazin-2-ylmethanone
    —— 1,6-dimethyl-N-[(1R)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-phenylethyl]-2-oxopyridine-3-carboxamide —— C23H23N5O3
    1,6-dimethyl-N-[(1R)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-phenylethyl]-2-oxopyridine-3-carboxamide
    —— 7-[(3S)-1-benzylpyrrolidin-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine —— C18H20N4
    7-[(3S)-1-benzylpyrrolidin-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine
    —— (3R)-N-[(1S)-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)ethyl]-5-oxo-1-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide —— C20H22N6O3
    (3R)-N-[(1S)-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)ethyl]-5-oxo-1-(pyridin-3-ylmethyl)pyrrolidine-3-carboxamide
    —— 4-methyl-N-[(1S)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-phenylethyl]pyrimidine-5-carboxamide —— C21H20N6O2
    4-methyl-N-[(1S)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-phenylethyl]pyrimidine-5-carboxamide
    —— 1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-methoxypropan-1-one —— C17H26F2N4O2
    1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-methoxypropan-1-one
    —— N-[(1R)-2-methyl-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)propyl]-3-(1,2-oxazol-5-yl)propanamide —— C17H21N5O3
    N-[(1R)-2-methyl-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)propyl]-3-(1,2-oxazol-5-yl)propanamide
    —— [4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-methoxythiophen-2-yl)methanone —— C19H24F2N4O2S
    [4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-methoxythiophen-2-yl)methanone
    —— N-[(1S)-1-(4-fluorophenyl)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)ethyl]pyridine-4-carboxamide —— C21H18FN5O2
    N-[(1S)-1-(4-fluorophenyl)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)ethyl]pyridine-4-carboxamide
    —— 1-[(2S)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-2-phenoxyethanone —— C20H22N4O2
    1-[(2S)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-2-phenoxyethanone
    —— (2,4-dimethyl-1,3-oxazol-5-yl)-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C19H24F3N5O2
    (2,4-dimethyl-1,3-oxazol-5-yl)-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— [4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-pyridin-2-ylmethanone —— C19H23F2N5O
    [4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-pyridin-2-ylmethanone
    —— N-[(1R)-1-(4-fluorophenyl)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)ethyl]cyclopentanecarboxamide —— C21H23FN4O2
    N-[(1R)-1-(4-fluorophenyl)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)ethyl]cyclopentanecarboxamide
    —— tert-butyl N-[(1R)-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)ethyl]carbamate —— C14H20N4O3
    tert-butyl N-[(1R)-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)ethyl]carbamate
    —— 5-[4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-methylpyridin-2-one —— C20H25F2N5O2
    5-[4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-methylpyridin-2-one
    —— 1-[(2S)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-3-(3-propan-2-yloxy-1,2-oxazol-5-yl)propan-1-one —— C21H27N5O3
    1-[(2S)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-3-(3-propan-2-yloxy-1,2-oxazol-5-yl)propan-1-one
    —— 2-methyl-5-[(3S)-1-(pyridin-3-ylmethyl)piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine —— C18H22N6
    2-methyl-5-[(3S)-1-(pyridin-3-ylmethyl)piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
    —— 1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-(1,2-oxazol-5-yl)propan-1-one —— C19H25F2N5O2
    1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-(1,2-oxazol-5-yl)propan-1-one
    —— 2-methyl-N-[(1S)-2-methyl-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)propyl]pyrazole-3-carboxamide —— C16H20N6O2
    2-methyl-N-[(1S)-2-methyl-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)propyl]pyrazole-3-carboxamide
    —— N-[(1S)-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)ethyl]pyridine-2-carboxamide —— C15H15N5O2
    N-[(1S)-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)ethyl]pyridine-2-carboxamide
    —— N-[(1S)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-phenylethyl]pyridine-2-carboxamide —— C21H19N5O2
    N-[(1S)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-phenylethyl]pyridine-2-carboxamide
    —— (2R)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(4-fluorophenoxy)propan-1-one —— C22H27F3N4O2
    (2R)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(4-fluorophenoxy)propan-1-one
    —— N-[(1S)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-phenylethyl]pyrazine-2-carboxamide —— C20H18N6O2
    N-[(1S)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-phenylethyl]pyrazine-2-carboxamide
    —— 1-[(3R)-3-[(4-fluorophenoxy)methyl]piperidin-1-yl]-3-(2,5,7-trimethylpyrazolo[1,5-a]pyrimidin-6-yl)propan-1-one —— C24H29FN4O2
    1-[(3R)-3-[(4-fluorophenoxy)methyl]piperidin-1-yl]-3-(2,5,7-trimethylpyrazolo[1,5-a]pyrimidin-6-yl)propan-1-one
    —— 1-[(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-(1,2-oxazol-5-yl)propan-1-one —— C19H24F3N5O2
    1-[(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-(1,2-oxazol-5-yl)propan-1-one
    —— [4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(1,3-thiazol-4-yl)methanone —— C17H20F3N5OS
    [4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(1,3-thiazol-4-yl)methanone
    —— [4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4-methyl-1,3-thiazol-5-yl)methanone —— C18H23F2N5OS
    [4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4-methyl-1,3-thiazol-5-yl)methanone
    —— 2-methyl-5-[(3S)-1-[[(3S)-oxolan-3-yl]methyl]piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine —— C17H25N5O
    2-methyl-5-[(3S)-1-[[(3S)-oxolan-3-yl]methyl]piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
    —— cyclohexyl-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C20H29F3N4O
    cyclohexyl-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— 2-cyclopentyl-1-[4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone —— C20H30F2N4O
    2-cyclopentyl-1-[4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]ethanone
    —— 1,5-dimethyl-N-[(1S)-2-methyl-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)propyl]pyrazole-4-sulfonamide —— C16H22N6O3S
    1,5-dimethyl-N-[(1S)-2-methyl-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)propyl]pyrazole-4-sulfonamide
    —— (2-methoxypyridin-4-yl)-[(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C20H24F3N5O2
    (2-methoxypyridin-4-yl)-[(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— (2S)-1-[4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-fluorophenoxy)propan-1-one —— C22H27F3N4O2
    (2S)-1-[4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2-fluorophenoxy)propan-1-one
    —— 1-[4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(4-methoxyphenoxy)ethanone —— C22H28F2N4O3
    1-[4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(4-methoxyphenoxy)ethanone
    —— 3-methoxy-1-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one —— C17H25F3N4O2
    3-methoxy-1-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]propan-1-one
    —— (4S)-5,5-dimethyl-4-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]oxolan-2-one —— C20H27F3N4O3
    (4S)-5,5-dimethyl-4-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]oxolan-2-one
    —— 5-[(3R)-1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)pyrrolidin-3-yl]-2-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C17H19N5O2S
    5-[(3R)-1-(2,4-dimethyl-1,3-thiazole-5-carbonyl)pyrrolidin-3-yl]-2-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— [4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(2,4-dimethyl-1,3-oxazol-5-yl)methanone —— C19H25F2N5O2
    [4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(2,4-dimethyl-1,3-oxazol-5-yl)methanone
    —— N-[(1R)-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)ethyl]-2-[(2S)-oxolan-2-yl]acetamide —— C15H20N4O3
    N-[(1R)-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)ethyl]-2-[(2S)-oxolan-2-yl]acetamide
    —— (3R)-N-[(1R)-2-methyl-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)propyl]-1,1-dioxothiolane-3-carboxamide —— C16H22N4O4S
    (3R)-N-[(1R)-2-methyl-1-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)propyl]-1,1-dioxothiolane-3-carboxamide
    —— [(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5-dimethylthiophen-3-yl)methanone —— C20H26F2N4OS
    [(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4,5-dimethylthiophen-3-yl)methanone