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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H23ClN8O
    2-amino-6-chloro-N-[4-[3-(dimethylamino)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(4-methylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C13H11FN6O
    2-amino-6-fluoro-N-(4-methylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-[4-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H24ClN7O2
    2-amino-6-chloro-N-[4-[4-(2-hydroxypropan-2-yl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[4-(morpholin-4-ylmethyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C22H26F2N8O2
    2-amino-6-fluoro-N-[5-fluoro-4-[4-(morpholin-4-ylmethyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-(cyanomethyl)-N-[4-[(3R)-pyrrolidin-3-yl]oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H18N8O2
    2-amino-6-(cyanomethyl)-N-[4-[(3R)-pyrrolidin-3-yl]oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-[4-(3,4-dimethylpiperazine-1-carbonyl)piperidin-1-yl]-5-fluoropyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C24H29F2N9O2
    2-amino-N-[4-[4-(3,4-dimethylpiperazine-1-carbonyl)piperidin-1-yl]-5-fluoropyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-piperidin-1-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H17F2N7O
    2-amino-6-fluoro-N-(5-fluoro-4-piperidin-1-ylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-(4-(4-(3,8-diazabicyclo[3.2.1]octane-3-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-94-3 C24H27F2N9O2
    N-(4-(4-(3,8-diazabicyclo[3.2.1]octane-3-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-(4-(3,3-difluoroazetidine-1-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-64-7 C21H20F4N8O2
    2-amino-N-(4-(4-(3,3-difluoroazetidine-1-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-(2-cyclopropylimidazol-1-yl)pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H15FN8O
    2-amino-N-[4-(2-cyclopropylimidazol-1-yl)pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[4-(3-methylpiperazine-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C23H27F2N9O2
    2-amino-6-fluoro-N-[5-fluoro-4-[4-(3-methylpiperazine-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-(4-(3-(dimethylamino)azetidine-1-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-31-8 C23H27F2N9O2
    2-amino-N-(4-(4-(3-(dimethylamino)azetidine-1-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— (R)-2-amino-6-fluoro-N-(5-fluoro-4-(4-((1-methylpyrrolidin-3-yl)oxy)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-75-3 C22H26F2N8O2
    (R)-2-amino-6-fluoro-N-(5-fluoro-4-(4-((1-methylpyrrolidin-3-yl)oxy)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-(4-(1-acetylpiperidin-4-yl)pyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-53-7 C19H20FN7O2
    N-(4-(1-acetylpiperidin-4-yl)pyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-(1,1-dioxothian-4-yl)oxypyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H17FN6O4S
    2-amino-N-[4-(1,1-dioxothian-4-yl)oxypyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-[4-[2-(dimethylamino)ethyl]pyrazol-1-yl]pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H20FN9O
    2-amino-N-[4-[4-[2-(dimethylamino)ethyl]pyrazol-1-yl]pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-(4-(4-(1,4-diazabicyclo[3.2.1]octane-4-carbonyl)piperidin-1-yl)-5-chloropyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-62-5 C24H27ClFN9O2
    N-(4-(4-(1,4-diazabicyclo[3.2.1]octane-4-carbonyl)piperidin-1-yl)-5-chloropyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-cyclopropyl-5-methoxypyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H15FN6O2
    2-amino-N-(4-cyclopropyl-5-methoxypyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[4-methyl-4-(4-methylpiperazine-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C24H29F2N9O2
    2-amino-6-fluoro-N-[5-fluoro-4-[4-methyl-4-(4-methylpiperazine-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(oxolan-3-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H15FN6O2
    2-amino-6-fluoro-N-[4-(oxolan-3-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[4-[(4-methylpiperazin-1-yl)methyl]piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C23H29F2N9O
    2-amino-6-fluoro-N-[5-fluoro-4-[4-[(4-methylpiperazin-1-yl)methyl]piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H15FN8O2
    2-amino-6-fluoro-N-[5-methoxy-4-(3-methylimidazol-4-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-(4-aminopiperidin-1-yl)pyridin-3-yl)-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-07-8 C17H19ClN8O
    2-amino-N-(4-(4-aminopiperidin-1-yl)pyridin-3-yl)-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-[4-(4-methylpiperazine-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C23H28FN9O2
    2-amino-6-fluoro-N-[4-[4-(4-methylpiperazine-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-[(2-oxopyrrolidin-1-yl)methyl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H16FN7O2
    2-amino-6-fluoro-N-[4-[(2-oxopyrrolidin-1-yl)methyl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— (3R)-3,5,7-trimethyl-1,2,3,3a,4,5,6,7-octahydropyrazolo[1,5-a]pyrimidine —— C9H19N3
    (3R)-3,5,7-trimethyl-1,2,3,3a,4,5,6,7-octahydropyrazolo[1,5-a]pyrimidine
    —— 2,4,5,6,7,7a-hexahydro-1-benzothiophen-3-yl-[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C25H34N6OS
    2,4,5,6,7,7a-hexahydro-1-benzothiophen-3-yl-[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [6-(aminomethylamino)pyridin-2-yl]-[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C23H31N9O
    [6-(aminomethylamino)pyridin-2-yl]-[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-[2-[bis(aminomethyl)amino]pyridin-4-yl]methanone —— C24H34N10O
    [(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-[2-[bis(aminomethyl)amino]pyridin-4-yl]methanone
    —— (6-aminopyridin-2-yl)-[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C22H28N8O
    (6-aminopyridin-2-yl)-[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1,6-dimethyl-2,3-dihydropyrazolo[3,4-b]pyridin-4-yl)methanone —— C25H33N9O
    [(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1,6-dimethyl-2,3-dihydropyrazolo[3,4-b]pyridin-4-yl)methanone
    —— [(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-[2-(1,2,4-triazolidin-4-yl)pyridin-4-yl]methanone —— C24H32N10O
    [(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-[2-(1,2,4-triazolidin-4-yl)pyridin-4-yl]methanone
    —— (E)-N-[[5-(5-acetylthiophen-2-yl)-7-chloro-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]prop-2-enamide —— C26H20ClF3N4O3S
    (E)-N-[[5-(5-acetylthiophen-2-yl)-7-chloro-2,3-dihydro-1-benzofuran-2-yl]methyl]-3-[2-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]prop-2-enamide
    —— [(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-4-yl)methanone —— C21H27N7O2
    [(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(3-methyl-1,2-oxazol-4-yl)methanone
    —— [(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(5-chloro-1H-pyrazol-4-yl)methanone —— C20H25ClN8O
    [(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(5-chloro-1H-pyrazol-4-yl)methanone
    —— [(2S)-2-[5-[(3S)-3-aminocyclopentyl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1-benzothiophen-3-yl)methanone —— C26H33N5OS
    [(2S)-2-[5-[(3S)-3-aminocyclopentyl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(4,5,6,7-tetrahydro-1-benzothiophen-3-yl)methanone
    —— tert-butyl (2S)-2-[5-(azetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carboxylate —— C19H27N5O2
    tert-butyl (2S)-2-[5-(azetidin-1-yl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carboxylate
    —— [2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanone —— C24H30N10O
    [2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanone
    —— N-[5-[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbonyl]-1H-imidazol-4-yl]propanamide —— C23H31N9O2
    N-[5-[(2S)-2-[5-[(3S)-3-aminopyrrolidin-1-yl]-6-methylpyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbonyl]-1H-imidazol-4-yl]propanamide
    —— N-(3-ethyl-1-bicyclo[3.3.1]nonanyl)-5-phenylspiro[5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidine-7,1'-cyclohexane]-3-carboxamide —— C29H40N4O
    N-(3-ethyl-1-bicyclo[3.3.1]nonanyl)-5-phenylspiro[5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidine-7,1'-cyclohexane]-3-carboxamide
    —— (5S,7R)-5-phenyl-N-[[(1S,5S)-3-tricyclo[3.3.1.03,7]nonanyl]methyl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C24H27F3N4O
    (5S,7R)-5-phenyl-N-[[(1S,5S)-3-tricyclo[3.3.1.03,7]nonanyl]methyl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2,2,2-trifluoro-N-[(1S)-3-[5-phenyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbonyl]cyclopentyl]acetamide —— C21H20F6N4O2
    2,2,2-trifluoro-N-[(1S)-3-[5-phenyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbonyl]cyclopentyl]acetamide
    —— 2-methyl-3-nitro-6-(4-nitro-1H-pyrazol-3-yl)pyrazolo[1,5-a]pyrimidine —— C10H7N7O4
    2-methyl-3-nitro-6-(4-nitro-1H-pyrazol-3-yl)pyrazolo[1,5-a]pyrimidine
    —— 1-(7,7-dimethyl-5-phenyl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidin-3-yl)ethanone —— C16H19N3O
    1-(7,7-dimethyl-5-phenyl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidin-3-yl)ethanone
    —— 1-(7,7-dimethyl-5-pyridin-2-yl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidin-3-yl)ethanone —— C15H18N4O
    1-(7,7-dimethyl-5-pyridin-2-yl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidin-3-yl)ethanone
    —— 4-benzyl-N,N,7,7-tetramethyl-5-phenyl-5,6-dihydropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C24H28N4O
    4-benzyl-N,N,7,7-tetramethyl-5-phenyl-5,6-dihydropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 3-(3-benzylpyrrolidin-1-yl)sulfonyl-7,7-dimethyl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidine —— C19H26N4O2S
    3-(3-benzylpyrrolidin-1-yl)sulfonyl-7,7-dimethyl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidine
    —— 1-(7,7-diethyl-5-phenyl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidin-3-yl)ethanone —— C18H23N3O
    1-(7,7-diethyl-5-phenyl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidin-3-yl)ethanone
    —— 2-[(5R)-7,7-dimethyl-5-phenyl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidin-3-yl]-5-(3-phenylpentan-3-yl)-1,3,4-oxadiazole —— C27H31N5O
    2-[(5R)-7,7-dimethyl-5-phenyl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidin-3-yl]-5-(3-phenylpentan-3-yl)-1,3,4-oxadiazole
    —— 2-(7,7-dimethyl-5-phenyl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidin-3-yl)-5-[3-(4-methylphenyl)pentan-3-yl]-2,3-dihydro-1,3,4-oxadiazole —— C28H35N5O
    2-(7,7-dimethyl-5-phenyl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidin-3-yl)-5-[3-(4-methylphenyl)pentan-3-yl]-2,3-dihydro-1,3,4-oxadiazole