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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— [(3S)-3-[(5S,7R)-5-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone —— C20H26F3N5O2
    [(3S)-3-[(5S,7R)-5-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone
    —— [(2S)-2-[(5S,7R)-5-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1-methylpyrazol-3-yl)methanone —— C21H29F3N6O
    [(2S)-2-[(5S,7R)-5-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1-methylpyrazol-3-yl)methanone
    —— (4R)-4-[(3R)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-propan-2-ylpyrrolidin-2-one —— C21H30F3N5O2
    (4R)-4-[(3R)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-propan-2-ylpyrrolidin-2-one
    —— [(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(2-methoxypyrimidin-5-yl)methanone —— C20H25F3N6O2
    [(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(2-methoxypyrimidin-5-yl)methanone
    —— (5S,7R)-5-tert-butyl-2-(1-prop-2-enylsulfonylpiperidin-4-yl)-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C19H29F3N4O2S
    (5S,7R)-5-tert-butyl-2-(1-prop-2-enylsulfonylpiperidin-4-yl)-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— [(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-methylthiophen-3-yl)methanone —— C19H24F2N4OS
    [(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-methylthiophen-3-yl)methanone
    —— [(3R)-3-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(6-methylpyridin-3-yl)methanone —— C23H30F3N5O
    [(3R)-3-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(6-methylpyridin-3-yl)methanone
    —— (5S,7R)-5-propan-2-yl-2-[(2R)-1-pyrrolidin-1-ylsulfonylpyrrolidin-2-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C18H28F3N5O2S
    (5S,7R)-5-propan-2-yl-2-[(2R)-1-pyrrolidin-1-ylsulfonylpyrrolidin-2-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— (5R,7R)-5-ethyl-2-(1-ethylsulfonylpiperidin-4-yl)-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C16H25F3N4O2S
    (5R,7R)-5-ethyl-2-(1-ethylsulfonylpiperidin-4-yl)-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— 5-ethyl-2-[(2S)-1-(1-ethylsulfonylpiperidine-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C21H31N5O4S
    5-ethyl-2-[(2S)-1-(1-ethylsulfonylpiperidine-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 4-[5-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-N,N-dimethylpiperidine-1-sulfonamide —— C18H26F3N5O2S
    4-[5-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-N,N-dimethylpiperidine-1-sulfonamide
    —— 1-[4-[5-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-(4-methylpyrazol-1-yl)ethanone —— C22H27F3N6O
    1-[4-[5-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-(4-methylpyrazol-1-yl)ethanone
    —— 2-[(2S)-1-[3-(3-ethoxy-1,2-oxazol-5-yl)propanoyl]piperidin-2-yl]-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H25N5O4
    2-[(2S)-1-[3-(3-ethoxy-1,2-oxazol-5-yl)propanoyl]piperidin-2-yl]-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5-ethyl-2-[(2S)-1-(5-methylpyrazine-2-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H22N6O2
    5-ethyl-2-[(2S)-1-(5-methylpyrazine-2-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(2R)-1-[3-(3-ethoxy-1,2-oxazol-5-yl)propanoyl]piperidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C21H27N5O4
    2-[(2R)-1-[3-(3-ethoxy-1,2-oxazol-5-yl)propanoyl]piperidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— Cyclopropyl-[4-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C17H19F3N4O
    Cyclopropyl-[4-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 6-ethyl-5-methyl-2-[(2R)-1-[2-(3-methyl-6-oxopyridazin-1-yl)acetyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C21H26N6O3
    6-ethyl-5-methyl-2-[(2R)-1-[2-(3-methyl-6-oxopyridazin-1-yl)acetyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5,6-dimethyl-2-[(2S)-1-(1-methyl-2-oxopyridine-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H23N5O3
    5,6-dimethyl-2-[(2S)-1-(1-methyl-2-oxopyridine-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2R)-1-(1,3-thiazole-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H21N5O2S
    6-ethyl-5-methyl-2-[(2R)-1-(1,3-thiazole-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(2S)-1-(3-ethyl-1,2-oxazole-5-carbonyl)piperidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H23N5O3
    2-[(2S)-1-(3-ethyl-1,2-oxazole-5-carbonyl)piperidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-Ethyl-1-[4-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]butan-1-one —— C19H25F3N4O
    2-Ethyl-1-[4-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]butan-1-one
    —— 6-ethyl-5-methyl-2-[(2S)-1-(1-methylsulfonylpiperidine-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C21H31N5O4S
    6-ethyl-5-methyl-2-[(2S)-1-(1-methylsulfonylpiperidine-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(2S)-1-(2-benzylsulfonylacetyl)piperidin-2-yl]-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C21H24N4O4S
    2-[(2S)-1-(2-benzylsulfonylacetyl)piperidin-2-yl]-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5-methyl-2-[(2S)-1-(1,3-thiazole-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C16H17N5O2S
    5-methyl-2-[(2S)-1-(1,3-thiazole-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2S)-1-(pyridine-2-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H23N5O2
    6-ethyl-5-methyl-2-[(2S)-1-(pyridine-2-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— (5-Aminopyridin-3-yl)-[4-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C21H23F3N6O
    (5-Aminopyridin-3-yl)-[4-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 5,6-dimethyl-2-[(2R)-1-[2-(4-methyl-1,2,5-oxadiazol-3-yl)acetyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H22N6O3
    5,6-dimethyl-2-[(2R)-1-[2-(4-methyl-1,2,5-oxadiazol-3-yl)acetyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5-ethyl-2-[(2S)-1-(1-methyl-6-oxopyridine-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H23N5O3
    5-ethyl-2-[(2S)-1-(1-methyl-6-oxopyridine-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2S)-1-[3-(1,2-oxazol-5-yl)propanoyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H25N5O3
    6-ethyl-5-methyl-2-[(2S)-1-[3-(1,2-oxazol-5-yl)propanoyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5-ethyl-2-[(2R)-1-(pyridine-2-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H21N5O2
    5-ethyl-2-[(2R)-1-(pyridine-2-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2S)-1-[4-(2-oxopyrrolidin-1-yl)butanoyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C22H31N5O3
    6-ethyl-5-methyl-2-[(2S)-1-[4-(2-oxopyrrolidin-1-yl)butanoyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 1-[(3R)-3-[(5R,7S)-5-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-phenylpropan-1-one —— C24H31F3N4O
    1-[(3R)-3-[(5R,7S)-5-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-phenylpropan-1-one
    —— 2,2-Dimethyl-1-[4-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]propan-1-one —— C18H23F3N4O
    2,2-Dimethyl-1-[4-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]propan-1-one
    —— cyclohexyl-[4-[(5S,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C20H29F3N4O
    cyclohexyl-[4-[(5S,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 5,6-dimethyl-2-[(2S)-1-(1,3-thiazole-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C17H19N5O2S
    5,6-dimethyl-2-[(2S)-1-(1,3-thiazole-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5-ethyl-2-[(2R)-1-[(2S)-oxolane-2-carbonyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H24N4O3
    5-ethyl-2-[(2R)-1-[(2S)-oxolane-2-carbonyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 1-[4-[5-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyrazol-1-ylethanone —— C21H25F3N6O
    1-[4-[5-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyrazol-1-ylethanone
    —— [4-[5-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(5-methylpyrazin-2-yl)methanone —— C22H25F3N6O
    [4-[5-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(5-methylpyrazin-2-yl)methanone
    —— 2-tert-butyl-5-[(3R)-1-(2-methylpyrazole-3-carbonyl)pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H24N6O2
    2-tert-butyl-5-[(3R)-1-(2-methylpyrazole-3-carbonyl)pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(2S)-1-(2-methoxypyridine-4-carbonyl)piperidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H23N5O3
    2-[(2S)-1-(2-methoxypyridine-4-carbonyl)piperidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(2R)-1-(2,4-dimethyl-1,3-oxazole-5-carbonyl)piperidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H23N5O3
    2-[(2R)-1-(2,4-dimethyl-1,3-oxazole-5-carbonyl)piperidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5,6-dimethyl-2-[(2R)-1-(2-methylpyrazole-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H22N6O2
    5,6-dimethyl-2-[(2R)-1-(2-methylpyrazole-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-Methyl-1-[4-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]propan-1-one —— C17H21F3N4O
    2-Methyl-1-[4-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]propan-1-one
    —— [4-[5-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(3,5-dimethyl-1,2-oxazol-4-yl)methanone —— C22H26F3N5O2
    [4-[5-Tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(3,5-dimethyl-1,2-oxazol-4-yl)methanone
    —— 5-methyl-2-[(2R)-1-(1-methyl-6-oxopyridine-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H21N5O3
    5-methyl-2-[(2R)-1-(1-methyl-6-oxopyridine-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— tert-butyl (3R)-3-(2-methyl-3-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate —— C21H26N4O2S
    tert-butyl (3R)-3-(2-methyl-3-thiophen-2-ylpyrazolo[1,5-a]pyrimidin-7-yl)piperidine-1-carboxylate
    —— 5-methyl-2-[(2S)-1-(pyrazolo[1,5-a]pyrimidine-3-carbonyl)pyrrolidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H17N7O2
    5-methyl-2-[(2S)-1-(pyrazolo[1,5-a]pyrimidine-3-carbonyl)pyrrolidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-2-[(2S)-1-[5-(methoxymethyl)furan-2-carbonyl]pyrrolidin-2-yl]-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H24N4O4
    6-ethyl-2-[(2S)-1-[5-(methoxymethyl)furan-2-carbonyl]pyrrolidin-2-yl]-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5,6-dimethyl-2-[(2R)-1-(pyridine-2-carbonyl)pyrrolidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H19N5O2
    5,6-dimethyl-2-[(2R)-1-(pyridine-2-carbonyl)pyrrolidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(2R)-1-[2-(2,6-dimethyl-4-oxo-1H-pyrimidin-5-yl)acetyl]pyrrolidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H24N6O3
    2-[(2R)-1-[2-(2,6-dimethyl-4-oxo-1H-pyrimidin-5-yl)acetyl]pyrrolidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one