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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (5S,7R)-2-[(2R)-1-[(3R)-thiolan-3-yl]pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C19H23F3N4S2
    (5S,7R)-2-[(2R)-1-[(3R)-thiolan-3-yl]pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— (5S,7R)-2-[(2S)-1-(thian-4-yl)pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C20H25F3N4S2
    (5S,7R)-2-[(2S)-1-(thian-4-yl)pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— [(2S)-oxolan-2-yl]-[(3S)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H19F3N4O2S
    [(2S)-oxolan-2-yl]-[(3S)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 1H-pyrazol-5-yl-[(3R)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H15F3N6OS
    1H-pyrazol-5-yl-[(3R)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— pyridin-4-yl-[(3S)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C21H16F3N5OS
    pyridin-4-yl-[(3S)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (5S,7R)-2-[1-[[(3S)-oxolan-3-yl]methyl]piperidin-4-yl]-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C21H27F3N4OS
    (5S,7R)-2-[1-[[(3S)-oxolan-3-yl]methyl]piperidin-4-yl]-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— (5S,7R)-2-[(2S)-1-[(3R)-thiolan-3-yl]pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C19H23F3N4S2
    (5S,7R)-2-[(2S)-1-[(3R)-thiolan-3-yl]pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— 1H-pyrazol-5-yl-[(2S)-2-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C20H17F3N6OS
    1H-pyrazol-5-yl-[(2S)-2-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 2-[(3S)-1-(pyrazolo[1,5-a]pyrimidine-3-carbonyl)piperidin-3-yl]-4-thiophen-2-yl-1H-pyrimidin-6-one —— C20H18N6O2S
    2-[(3S)-1-(pyrazolo[1,5-a]pyrimidine-3-carbonyl)piperidin-3-yl]-4-thiophen-2-yl-1H-pyrimidin-6-one
    —— 2-[(2S)-1-[[(3S)-oxolan-3-yl]methyl]piperidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H23F3N4OS
    2-[(2S)-1-[[(3S)-oxolan-3-yl]methyl]piperidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-imidazol-1-yl-1-[(3S)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C20H17F3N6OS
    2-imidazol-1-yl-1-[(3S)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— cyclopropyl-[(2R)-2-[(5S,7R)-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C20H23F3N4OS
    cyclopropyl-[(2R)-2-[(5S,7R)-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 2-[(2S)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H21F3N4OS
    2-[(2S)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-hydroxy-1-[4-[(5S,7R)-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone —— C18H21F3N4O2S
    2-hydroxy-1-[4-[(5S,7R)-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone
    —— (5S,7R)-2-[(2R)-1-(thian-4-yl)pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C20H25F3N4S2
    (5S,7R)-2-[(2R)-1-(thian-4-yl)pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— cyclopropyl-[(2R)-2-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C20H19F3N4OS
    cyclopropyl-[(2R)-2-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 2-[(3S)-1-(pyrazolo[1,5-a]pyrimidine-2-carbonyl)piperidin-3-yl]-6-thiophen-2-yl-1H-pyrimidin-4-one —— C20H18N6O2S
    2-[(3S)-1-(pyrazolo[1,5-a]pyrimidine-2-carbonyl)piperidin-3-yl]-6-thiophen-2-yl-1H-pyrimidin-4-one
    —— [(2R)-oxolan-2-yl]-[(3R)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H19F3N4O2S
    [(2R)-oxolan-2-yl]-[(3R)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 2-[(3S)-1-(pyridin-4-ylmethyl)pyrrolidin-3-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H18F3N5S
    2-[(3S)-1-(pyridin-4-ylmethyl)pyrrolidin-3-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 1H-pyrazol-5-yl-[(3S)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H15F3N6OS
    1H-pyrazol-5-yl-[(3S)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (5S,7R)-2-[1-[[(3R)-oxolan-3-yl]methyl]piperidin-4-yl]-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C21H27F3N4OS
    (5S,7R)-2-[1-[[(3R)-oxolan-3-yl]methyl]piperidin-4-yl]-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— cyclopropyl-[(2S)-2-[(5S,7R)-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C20H23F3N4OS
    cyclopropyl-[(2S)-2-[(5S,7R)-5-thiophen-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [(2R)-oxolan-2-yl]-[(3S)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H19F3N4O2S
    [(2R)-oxolan-2-yl]-[(3S)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 2-[(3R)-1-(pyrazolo[1,5-a]pyrimidine-3-carbonyl)piperidin-3-yl]-4-thiophen-2-yl-1H-pyrimidin-6-one —— C20H18N6O2S
    2-[(3R)-1-(pyrazolo[1,5-a]pyrimidine-3-carbonyl)piperidin-3-yl]-4-thiophen-2-yl-1H-pyrimidin-6-one
    —— 5-[(3S)-1-(2,3-dihydro-1,4-dioxin-5-ylmethyl)piperidin-3-yl]-2-(furan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine —— C20H23N5O3
    5-[(3S)-1-(2,3-dihydro-1,4-dioxin-5-ylmethyl)piperidin-3-yl]-2-(furan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
    —— 2-(furan-2-yl)-5-[(3S)-1-(furan-3-ylmethyl)piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine —— C20H21N5O2
    2-(furan-2-yl)-5-[(3S)-1-(furan-3-ylmethyl)piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
    —— 2-(furan-2-yl)-5-[(3R)-1-(furan-3-ylmethyl)piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine —— C20H21N5O2
    2-(furan-2-yl)-5-[(3R)-1-(furan-3-ylmethyl)piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
    —— 3-bromo-N-(2-morpholin-4-ylethyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide —— C18H17BrF3N5O2S
    3-bromo-N-(2-morpholin-4-ylethyl)-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
    —— N-[(2R)-butan-2-yl]-N-[(3R)-1,1-dioxothiolan-3-yl]-2-(1-methyl-4-oxopyrazolo[3,4-d]pyrimidin-5-yl)acetamide —— C16H23N5O4S
    N-[(2R)-butan-2-yl]-N-[(3R)-1,1-dioxothiolan-3-yl]-2-(1-methyl-4-oxopyrazolo[3,4-d]pyrimidin-5-yl)acetamide
    —— N-[(2S)-butan-2-yl]-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(1-methyl-4-oxopyrazolo[3,4-d]pyrimidin-5-yl)acetamide —— C16H23N5O4S
    N-[(2S)-butan-2-yl]-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(1-methyl-4-oxopyrazolo[3,4-d]pyrimidin-5-yl)acetamide
    —— N-[(3R)-1,1-dioxothiolan-3-yl]-2-(1-methyl-4-oxopyrazolo[3,4-d]pyrimidin-5-yl)-N-(2-methylpropyl)acetamide —— C16H23N5O4S
    N-[(3R)-1,1-dioxothiolan-3-yl]-2-(1-methyl-4-oxopyrazolo[3,4-d]pyrimidin-5-yl)-N-(2-methylpropyl)acetamide
    —— N-[(2S)-butan-2-yl]-N-[(3R)-1,1-dioxothiolan-3-yl]-2-(1-methyl-4-oxopyrazolo[3,4-d]pyrimidin-5-yl)acetamide —— C16H23N5O4S
    N-[(2S)-butan-2-yl]-N-[(3R)-1,1-dioxothiolan-3-yl]-2-(1-methyl-4-oxopyrazolo[3,4-d]pyrimidin-5-yl)acetamide
    —— (3-Chloropyrazolo[1,5-a]pyrimidin-2-yl)-[4-(2-fluoropyridin-3-yl)-4-hydroxypiperidin-1-yl]methanone —— C17H15ClFN5O2
    (3-Chloropyrazolo[1,5-a]pyrimidin-2-yl)-[4-(2-fluoropyridin-3-yl)-4-hydroxypiperidin-1-yl]methanone
    —— 5-Cyclopropyl-12-[(2,3-difluorophenyl)methyl]-2,6,7,12-tetrazatricyclo[7.4.0.03,7]trideca-1(9),2,4-trien-8-one —— C19H18F2N4O
    5-Cyclopropyl-12-[(2,3-difluorophenyl)methyl]-2,6,7,12-tetrazatricyclo[7.4.0.03,7]trideca-1(9),2,4-trien-8-one
    —— N-cyclohexyl-1-[(2,4-dichlorophenyl)methyl]pyrazolo[3,4-d]pyrimidin-4-amine —— C18H19Cl2N5
    N-cyclohexyl-1-[(2,4-dichlorophenyl)methyl]pyrazolo[3,4-d]pyrimidin-4-amine
    —— [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2R)-2-(1-methylpyrazol-3-yl)azepan-1-yl]methanone —— C21H24F2N6O
    [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2R)-2-(1-methylpyrazol-3-yl)azepan-1-yl]methanone
    —— 2-[(3R)-1-[(1-methylpyrazol-4-yl)methyl]piperidin-3-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H21F3N6S
    2-[(3R)-1-[(1-methylpyrazol-4-yl)methyl]piperidin-3-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 3-chloro-5-(furan-2-yl)-N-(3-methylpent-1-yn-3-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide —— C18H14ClF3N4O2
    3-chloro-5-(furan-2-yl)-N-(3-methylpent-1-yn-3-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
    —— 2-[(3S)-1-[(1-methylpyrazol-4-yl)methyl]piperidin-3-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H21F3N6S
    2-[(3S)-1-[(1-methylpyrazol-4-yl)methyl]piperidin-3-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-(furan-2-yl)-N-(3-methylpent-1-yn-3-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H15F3N4O2
    5-(furan-2-yl)-N-(3-methylpent-1-yn-3-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— [(2S)-2-(4-chloro-1-methylpyrazol-3-yl)azepan-1-yl]-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone —— C21H23ClF2N6O
    [(2S)-2-(4-chloro-1-methylpyrazol-3-yl)azepan-1-yl]-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
    —— [(2R)-2-(4-chloro-1-methylpyrazol-3-yl)azepan-1-yl]-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone —— C21H23ClF2N6O
    [(2R)-2-(4-chloro-1-methylpyrazol-3-yl)azepan-1-yl]-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]methanone
    —— [(2S)-2-(4-chloro-1-methylpyrazol-3-yl)azepan-1-yl]-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone —— C21H23ClF2N6O
    [(2S)-2-(4-chloro-1-methylpyrazol-3-yl)azepan-1-yl]-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone
    —— [(2R)-2-(4-chloro-1-methylpyrazol-3-yl)azepan-1-yl]-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone —— C21H23ClF2N6O
    [(2R)-2-(4-chloro-1-methylpyrazol-3-yl)azepan-1-yl]-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone
    —— [(2R)-2-(4-chloro-2-methylpyrazol-3-yl)azepan-1-yl]-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone —— C21H23ClF2N6O
    [(2R)-2-(4-chloro-2-methylpyrazol-3-yl)azepan-1-yl]-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone
    —— 2-[1-[(2-Methylpyrimidin-5-yl)methyl]piperidin-4-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H25F3N6
    2-[1-[(2-Methylpyrimidin-5-yl)methyl]piperidin-4-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(2S)-1-[(2-methylpyrimidin-5-yl)methyl]pyrrolidin-2-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H23F3N6
    2-[(2S)-1-[(2-methylpyrimidin-5-yl)methyl]pyrrolidin-2-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (2S)-2-methyl-3-(2-methylimidazol-1-yl)-1-[(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one —— C22H27F3N6O
    (2S)-2-methyl-3-(2-methylimidazol-1-yl)-1-[(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one
    —— (2S)-2-methyl-3-(2-methylimidazol-1-yl)-1-[(3S)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one —— C22H27F3N6O
    (2S)-2-methyl-3-(2-methylimidazol-1-yl)-1-[(3S)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one
    —— (2R)-2-methyl-3-(2-methylimidazol-1-yl)-1-[(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one —— C22H27F3N6O
    (2R)-2-methyl-3-(2-methylimidazol-1-yl)-1-[(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one