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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H21F2N7O2
    2-amino-6-fluoro-N-[5-fluoro-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-(4-(3-ethoxyazetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-81-8 C23H27FN8O3
    2-amino-N-(4-(4-(3-ethoxyazetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[1-(oxetan-3-yl)piperidin-4-yl]oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H21F2N7O3
    2-amino-6-fluoro-N-[5-fluoro-4-[1-(oxetan-3-yl)piperidin-4-yl]oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-(3,5-dimethylimidazol-4-yl)pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H15FN8O
    2-amino-N-[4-(3,5-dimethylimidazol-4-yl)pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(1-methylpyrrolo[3,2-c]pyridin-7-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C15H12FN7O
    2-amino-6-fluoro-N-(1-methylpyrrolo[3,2-c]pyridin-7-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-(4-(3-hydroxyazetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-44-3 C21H22F2N8O3
    2-amino-6-fluoro-N-(5-fluoro-4-(4-(3-hydroxyazetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-[4-(1,2,4-oxadiazol-3-yl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H18FN9O2
    2-amino-6-fluoro-N-[4-[4-(1,2,4-oxadiazol-3-yl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(4-(4-(morpholine-4-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-75-0 C22H25FN8O3
    2-amino-6-fluoro-N-(4-(4-(morpholine-4-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-(4-(4-morpholinopiperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-14-0 C21H25ClN8O2
    2-amino-6-chloro-N-(4-(4-morpholinopiperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[4-(2-pyrrolidin-1-ylethoxy)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C23H28F2N8O2
    2-amino-6-fluoro-N-[5-fluoro-4-[4-(2-pyrrolidin-1-ylethoxy)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 4-(1-(3-(2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamido)-5-fluoropyridin-4-yl)piperidine-4-carbonyl)-1-methylpiperazine 1-oxide 1613196-85-2 C23H27F2N9O3
    4-(1-(3-(2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamido)-5-fluoropyridin-4-yl)piperidine-4-carbonyl)-1-methylpiperazine 1-oxide
    —— 2-amino-6-fluoro-N-[4-(1-methylpyrazol-3-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H13FN8O
    2-amino-6-fluoro-N-[4-(1-methylpyrazol-3-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(2-oxa-7-azaspiro[3.5]nonan-7-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H20FN7O2
    2-amino-6-fluoro-N-[4-(2-oxa-7-azaspiro[3.5]nonan-7-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-(4-(aminomethyl)piperidin-1-yl)pyridin-3-yl)-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-12-5 C18H21ClN8O
    2-amino-N-(4-(4-(aminomethyl)piperidin-1-yl)pyridin-3-yl)-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-(4-(4-(1 ,4-diazabicyclo[3.2.1]octane-4-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-fluoropyrazolo [1,5-a]pyrimidine-3-carboxamide 1613196-47-6 C24H27F2N9O2
    N-(4-(4-(1 ,4-diazabicyclo[3.2.1]octane-4-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-fluoropyrazolo [1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(4-(4-((1-methylpiperidin-4-yl)oxy)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-76-4 C23H29FN8O2
    2-amino-6-fluoro-N-(4-(4-((1-methylpiperidin-4-yl)oxy)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(4-pyrrolidin-3-yloxypiperidin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C21H25FN8O2
    2-amino-6-fluoro-N-[4-(4-pyrrolidin-3-yloxypiperidin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-methyl-4-(4-(piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-98-7 C23H28FN9O2
    2-amino-6-fluoro-N-(5-methyl-4-(4-(piperazine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[3-(4-methylpiperazine-1-carbonyl)pyrrolidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C22H25F2N9O2
    2-amino-6-fluoro-N-[5-fluoro-4-[3-(4-methylpiperazine-1-carbonyl)pyrrolidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-(4-(5-methyloctahydropyrrolo[3,4-c]pyrrole-2-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-27-2 C25H29F2N9O2
    2-amino-6-fluoro-N-(5-fluoro-4-(4-(5-methyloctahydropyrrolo[3,4-c]pyrrole-2-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[4-(3,3,4-trimethylpiperazine-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C25H31F2N9O2
    2-amino-6-fluoro-N-[5-fluoro-4-[4-(3,3,4-trimethylpiperazine-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-(cyanomethyl)-N-(4-methoxypyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C15H13N7O2
    2-amino-6-(cyanomethyl)-N-(4-methoxypyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(3-methylpyrazin-2-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H13FN8O
    2-amino-6-fluoro-N-[4-(3-methylpyrazin-2-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(4-methylpyridazin-3-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H13FN8O
    2-amino-6-fluoro-N-[4-(4-methylpyridazin-3-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-(4-(3-cyanoazetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-71-6 C22H22FN9O2
    2-amino-N-(4-(4-(3-cyanoazetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-(4-((2-(dimethylamino)ethyl)(methyl)carbamoyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-37-4 C23H29F2N9O2
    2-amino-N-(4-(4-((2-(dimethylamino)ethyl)(methyl)carbamoyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[4-(4-methyl-1,4-diazepane-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C24H29F2N9O2
    2-amino-6-fluoro-N-[5-fluoro-4-[4-(4-methyl-1,4-diazepane-1-carbonyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-(2-oxa-7-azaspiro[3.5]nonan-7-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H19F2N7O2
    2-amino-6-fluoro-N-[5-fluoro-4-(2-oxa-7-azaspiro[3.5]nonan-7-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-[4-(methylsulfonylmethyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H22FN7O3S
    2-amino-6-fluoro-N-[4-[4-(methylsulfonylmethyl)piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-(3-ethylimidazol-4-yl)pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H15FN8O
    2-amino-N-[4-(3-ethylimidazol-4-yl)pyridin-3-yl]-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(5-methylpyrimidin-4-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H13FN8O
    2-amino-6-fluoro-N-[4-(5-methylpyrimidin-4-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-(4-(azetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-67-0 C21H23FN8O2
    2-amino-N-(4-(4-(azetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-(4-(3-cyanoazetidine-1-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C22H21F2N9O2
    2-amino-N-(4-(4-(3-cyanoazetidine-1-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(3-methylsulfonylpiperidin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H20FN7O3S
    2-amino-6-fluoro-N-[4-(3-methylsulfonylpiperidin-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-(4-(3-methoxy-3-methylazetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-65-8 C23H26F2N8O3
    2-amino-6-fluoro-N-(5-fluoro-4-(4-(3-methoxy-3-methylazetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[5-fluoro-4-[1-(oxetan-3-yl)-3,6-dihydro-2H-pyridin-4-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H19F2N7O2
    2-amino-6-fluoro-N-[5-fluoro-4-[1-(oxetan-3-yl)-3,6-dihydro-2H-pyridin-4-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-(4-(4-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)piperidin-1-yl)pyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-78-3 C23H25FN8O3
    N-(4-(4-(2-oxa-6-azaspiro[3.3]heptane-6-carbonyl)piperidin-1-yl)pyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-(4-(3-fluoroazetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-60-3 C21H21F3N8O2
    2-amino-6-fluoro-N-(5-fluoro-4-(4-(3-fluoroazetidine-1-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-[4-(2-aminoethoxy)pyridin-3-yl]-6-(cyanomethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H16N8O2
    2-amino-N-[4-(2-aminoethoxy)pyridin-3-yl]-6-(cyanomethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-(1-(1-cyanocyclopropanecarbonyl)piperidin-4-yl)pyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-55-9 C22H21FN8O2
    2-amino-N-(4-(1-(1-cyanocyclopropanecarbonyl)piperidin-4-yl)pyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-(1-cyanocyclopropyl)-N-[5-fluoro-4-[4-[(4-methylpiperazin-1-yl)methyl]piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C27H33FN10O
    2-amino-6-(1-cyanocyclopropyl)-N-[5-fluoro-4-[4-[(4-methylpiperazin-1-yl)methyl]piperidin-1-yl]pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-(4-(4-((5S)-1,4-diazabicyclo[3.2.1]octane-4-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-63-6 C24H27F2N9O2
    N-(4-(4-((5S)-1,4-diazabicyclo[3.2.1]octane-4-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-(4-(4-(1-oxidothiomorpholino)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-10-6 C21H25ClN8O2S
    2-amino-6-chloro-N-(4-(4-(1-oxidothiomorpholino)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-(5-fluoro-4-(4-(octahydropyrrolo[1,2-a]pyrazine-2-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-23-8 C25H29F2N9O2
    2-amino-6-fluoro-N-(5-fluoro-4-(4-(octahydropyrrolo[1,2-a]pyrazine-2-carbonyl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-[4-(4-methyl-1,4-diazepan-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C18H21ClN8O
    2-amino-6-chloro-N-[4-(4-methyl-1,4-diazepan-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— N-(4-(4-(1,4-diazabicyclo[3.2.2]nonane-4-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide 1613196-77-2 C25H29ClFN9O2
    N-(4-(4-(1,4-diazabicyclo[3.2.2]nonane-4-carbonyl)piperidin-1-yl)-5-fluoropyridin-3-yl)-2-amino-6-chloropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-N-(4-cyclopropylpyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C15H13FN6O
    2-amino-N-(4-cyclopropylpyridin-3-yl)-6-fluoropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-[4-[(3S)-1-(2-methoxyethyl)piperidin-3-yl]oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C20H24ClN7O3
    2-amino-6-chloro-N-[4-[(3S)-1-(2-methoxyethyl)piperidin-3-yl]oxypyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-fluoro-N-[4-(5-methylpyrazol-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide —— C16H13FN8O
    2-amino-6-fluoro-N-[4-(5-methylpyrazol-1-yl)pyridin-3-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— 2-amino-6-chloro-N-(4-(4-(3-methoxyazetidin-1-yl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide 1613197-17-3 C21H25ClN8O2
    2-amino-6-chloro-N-(4-(4-(3-methoxyazetidin-1-yl)piperidin-1-yl)pyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide