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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 2-[2-[4-[5-Ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-oxoethyl]-6-methylpyridazin-3-one —— C21H23F3N6O2
    2-[2-[4-[5-Ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-oxoethyl]-6-methylpyridazin-3-one
    —— 1-benzothiophen-2-yl-[(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C22H19F3N4OS
    1-benzothiophen-2-yl-[(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 1-[4-[5-Ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone —— C19H21F3N6O2
    1-[4-[5-Ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone
    —— 5-Ethyl-2-[1-[(2-methoxypyrimidin-5-yl)methyl]piperidin-4-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H23F3N6O
    5-Ethyl-2-[1-[(2-methoxypyrimidin-5-yl)methyl]piperidin-4-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-ethyl-2-[(2S)-1-[[2-methoxy-5-(methoxymethyl)phenyl]methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C23H27F3N4O2
    5-ethyl-2-[(2S)-1-[[2-methoxy-5-(methoxymethyl)phenyl]methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-ethyl-2-[(2R)-1-[(3-methylpyridin-4-yl)methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H22F3N5
    5-ethyl-2-[(2R)-1-[(3-methylpyridin-4-yl)methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1-propan-2-ylpyrazol-4-yl)methanone —— C20H23F3N6O
    [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1-propan-2-ylpyrazol-4-yl)methanone
    —— [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-pyridin-2-ylmethanone —— C20H20F3N5O
    [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-pyridin-2-ylmethanone
    —— cyclohexen-1-yl-[(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H23F3N4O
    cyclohexen-1-yl-[(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 1-benzofuran-2-yl-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C22H19F3N4O2
    1-benzofuran-2-yl-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyridin-3-yloxyethanone —— C20H20F3N5O2
    1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyridin-3-yloxyethanone
    —— (3R)-1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylbutan-1-one —— C20H23F3N6O
    (3R)-1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylbutan-1-one
    —— 2-[(2R)-1-[(5-tert-butyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl]-5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H27F3N6
    2-[(2R)-1-[(5-tert-butyl-1H-pyrazol-4-yl)methyl]pyrrolidin-2-yl]-5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-(3,5-dimethylpyrazol-1-yl)-1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone —— C21H25F3N6O
    2-(3,5-dimethylpyrazol-1-yl)-1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone
    —— [(3R)-1,1-dioxothiolan-3-yl]-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C18H21F3N4O3S
    [(3R)-1,1-dioxothiolan-3-yl]-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyridin-4-ylmethanone —— C19H18F3N5O
    [(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyridin-4-ylmethanone
    —— 5-ethyl-2-[(2S)-1-[[3-(2-methoxyethoxy)phenyl]methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C23H27F3N4O2
    5-ethyl-2-[(2S)-1-[[3-(2-methoxyethoxy)phenyl]methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-ethyl-2-[(2S)-1-(1-ethylpiperidin-4-yl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H28F3N5
    5-ethyl-2-[(2S)-1-(1-ethylpiperidin-4-yl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(3R)-1-[(4-ethoxy-3-methoxyphenyl)methyl]pyrrolidin-3-yl]-5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C23H27F3N4O2
    2-[(3R)-1-[(4-ethoxy-3-methoxyphenyl)methyl]pyrrolidin-3-yl]-5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-ethyl-2-[(2S)-1-(pyridin-2-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H20F3N5
    5-ethyl-2-[(2S)-1-(pyridin-2-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(3R)-1-[(3-ethoxy-4-methoxyphenyl)methyl]pyrrolidin-3-yl]-5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C23H27F3N4O2
    2-[(3R)-1-[(3-ethoxy-4-methoxyphenyl)methyl]pyrrolidin-3-yl]-5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(3S)-1-[(4-ethoxy-3-methoxyphenyl)methyl]pyrrolidin-3-yl]-5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C23H27F3N4O2
    2-[(3S)-1-[(4-ethoxy-3-methoxyphenyl)methyl]pyrrolidin-3-yl]-5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 4-(3,5-dimethylpyrazol-1-yl)-1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]butan-1-one —— C22H27F3N6O
    4-(3,5-dimethylpyrazol-1-yl)-1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]butan-1-one
    —— [(3R)-1,1-dioxothiolan-3-yl]-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C18H21F3N4O3S
    [(3R)-1,1-dioxothiolan-3-yl]-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1,3-thiazol-4-yl)methanone —— C17H16F3N5OS
    [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1,3-thiazol-4-yl)methanone
    —— (4S)-4-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]-1-propan-2-ylpyrrolidin-2-one —— C21H26F3N5O2
    (4S)-4-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]-1-propan-2-ylpyrrolidin-2-one
    —— [4-[5-Ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(2-methoxypyrimidin-5-yl)methanone —— C20H21F3N6O2
    [4-[5-Ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(2-methoxypyrimidin-5-yl)methanone
    —— 1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-(3,4,5-trimethylpyrazol-1-yl)propan-1-one —— C22H27F3N6O
    1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-(3,4,5-trimethylpyrazol-1-yl)propan-1-one
    —— 1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-2-ylethanone —— C21H22F3N5O
    1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-2-ylethanone
    —— 5-ethyl-2-[(2R)-1-[(2-methylpyrimidin-5-yl)methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H21F3N6
    5-ethyl-2-[(2R)-1-[(2-methylpyrimidin-5-yl)methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1-methylpyrazol-4-yl)methanone —— C18H19F3N6O
    [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1-methylpyrazol-4-yl)methanone
    —— 5-ethyl-2-[(2S)-1-[(2-methylpyrimidin-5-yl)methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H21F3N6
    5-ethyl-2-[(2S)-1-[(2-methylpyrimidin-5-yl)methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methyl-5-propan-2-ylpyrazol-3-yl)methanone —— C21H25F3N6O
    [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methyl-5-propan-2-ylpyrazol-3-yl)methanone
    —— [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-pyridin-2-ylmethanone —— C20H20F3N5O
    [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-pyridin-2-ylmethanone
    —— (2S)-3-(3,5-dimethylpyrazol-1-yl)-1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-methylpropan-1-one —— C22H27F3N6O
    (2S)-3-(3,5-dimethylpyrazol-1-yl)-1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-methylpropan-1-one
    —— [(1R)-cyclohex-3-en-1-yl]-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H23F3N4O
    [(1R)-cyclohex-3-en-1-yl]-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(6-methylpyridin-3-yl)methanone —— C20H20F3N5O
    [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(6-methylpyridin-3-yl)methanone
    —— 1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylpropan-1-one —— C19H21F3N6O
    1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylpropan-1-one
    —— 5-ethyl-2-[(3S)-1-(pyridin-3-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H22F3N5
    5-ethyl-2-[(3S)-1-(pyridin-3-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-ethyl-2-[(3R)-1-(pyridin-3-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H22F3N5
    5-ethyl-2-[(3R)-1-(pyridin-3-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (4,5-dimethylthiophen-3-yl)-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C21H23F3N4OS
    (4,5-dimethylthiophen-3-yl)-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 5-ethyl-2-[(3R)-1-[(3-methoxyphenyl)methyl]pyrrolidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H23F3N4O
    5-ethyl-2-[(3R)-1-[(3-methoxyphenyl)methyl]pyrrolidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— [(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methoxypyrimidin-5-yl)methanone —— C19H19F3N6O2
    [(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methoxypyrimidin-5-yl)methanone
    —— 5-ethyl-2-[(2R)-1-(1-ethylpiperidin-4-yl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H28F3N5
    5-ethyl-2-[(2R)-1-(1-ethylpiperidin-4-yl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-ethyl-2-[(3S)-1-[(3-methoxyphenyl)methyl]pyrrolidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H23F3N4O
    5-ethyl-2-[(3S)-1-[(3-methoxyphenyl)methyl]pyrrolidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (2R)-3-(3,5-dimethylpyrazol-1-yl)-1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-methylpropan-1-one —— C22H27F3N6O
    (2R)-3-(3,5-dimethylpyrazol-1-yl)-1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-methylpropan-1-one
    —— (2,4-dimethyl-1,3-thiazol-5-yl)-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C20H22F3N5OS
    (2,4-dimethyl-1,3-thiazol-5-yl)-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 2-(3,5-dimethylpyrazol-1-yl)-1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone —— C21H25F3N6O
    2-(3,5-dimethylpyrazol-1-yl)-1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone
    —— 1-benzothiophen-2-yl-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C22H19F3N4OS
    1-benzothiophen-2-yl-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 5-ethyl-2-[(3R)-1-[(2-methylpyrimidin-5-yl)methyl]piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H23F3N6
    5-ethyl-2-[(3R)-1-[(2-methylpyrimidin-5-yl)methyl]piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine