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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— 1-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-phenylpropan-1-one —— C22H27F3N4O
    1-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-3-phenylpropan-1-one
    —— cyclopropyl-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C17H23F3N4O
    cyclopropyl-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 5-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]-1-methylpyridin-2-one —— C20H24F3N5O2
    5-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]-1-methylpyridin-2-one
    —— (5-methylthiophen-3-yl)-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C19H23F3N4OS
    (5-methylthiophen-3-yl)-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— (2,4-dimethylpyrimidin-5-yl)-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H25F3N6O
    (2,4-dimethylpyrimidin-5-yl)-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 1-[(2R)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyrazol-1-ylethanone —— C19H25F3N6O
    1-[(2R)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyrazol-1-ylethanone
    —— 1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-methoxyethanone —— C16H23F3N4O2
    1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-methoxyethanone
    —— (5-ethyl-3-methyl-1,2-oxazol-4-yl)-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H26F3N5O2
    (5-ethyl-3-methyl-1,2-oxazol-4-yl)-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 2-[(2R)-oxolan-2-yl]-1-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C20H29F3N4O2
    2-[(2R)-oxolan-2-yl]-1-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methylpyrazol-3-yl)methanone —— C18H23F3N6O
    [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methylpyrazol-3-yl)methanone
    —— (4-methyl-1,3-thiazol-5-yl)-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C17H20F3N5OS
    (4-methyl-1,3-thiazol-5-yl)-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(4-methyl-1,3-thiazol-5-yl)methanone —— C18H22F3N5OS
    [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(4-methyl-1,3-thiazol-5-yl)methanone
    —— 2-(4-methyl-1,2,5-oxadiazol-3-yl)-1-[(2R)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C19H25F3N6O2
    2-(4-methyl-1,2,5-oxadiazol-3-yl)-1-[(2R)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— cyclohexyl-[(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C20H29F3N4O
    cyclohexyl-[(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— [(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-pyridin-3-ylmethanone —— C19H22F3N5O
    [(3S)-3-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-pyridin-3-ylmethanone
    —— 1-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyrazol-1-ylethanone —— C19H25F3N6O
    1-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyrazol-1-ylethanone
    —— (1-methylpyrazol-3-yl)-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H25F3N6O
    (1-methylpyrazol-3-yl)-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— cyclopropyl-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C16H21F3N4O
    cyclopropyl-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-cyclopropylmethanone —— C20H30F2N4O
    [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-cyclopropylmethanone
    —— (4-ethylthiadiazol-5-yl)-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C18H23F3N6OS
    (4-ethylthiadiazol-5-yl)-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 5,6-dimethyl-2-[(2S)-1-[(3S)-oxolane-3-carbonyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H24N4O3
    5,6-dimethyl-2-[(2S)-1-[(3S)-oxolane-3-carbonyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(2R)-1-(5,6-dimethyl-2-oxo-1H-pyridine-3-carbonyl)piperidin-2-yl]-6-ethyl-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C22H27N5O3
    2-[(2R)-1-(5,6-dimethyl-2-oxo-1H-pyridine-3-carbonyl)piperidin-2-yl]-6-ethyl-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-methyl-5-[(3R)-1-(3,4,5-trimethoxybenzoyl)pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C21H24N4O5
    2-methyl-5-[(3R)-1-(3,4,5-trimethoxybenzoyl)pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2R)-1-(1-methyl-6-oxopyridine-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C21H25N5O3
    6-ethyl-5-methyl-2-[(2R)-1-(1-methyl-6-oxopyridine-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2R)-1-[3-(1,2-oxazol-5-yl)propanoyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H25N5O3
    6-ethyl-5-methyl-2-[(2R)-1-[3-(1,2-oxazol-5-yl)propanoyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5,6-dimethyl-2-[(2R)-1-(1-methylpyrazole-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H22N6O2
    5,6-dimethyl-2-[(2R)-1-(1-methylpyrazole-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-tert-butyl-5-[(3S)-1-[3-(1,2-oxazol-5-yl)propanoyl]pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H25N5O3
    2-tert-butyl-5-[(3S)-1-[3-(1,2-oxazol-5-yl)propanoyl]pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2R)-1-(4-methylthiadiazole-5-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H22N6O2S
    6-ethyl-5-methyl-2-[(2R)-1-(4-methylthiadiazole-5-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(2S)-1-(5,6-dimethyl-2-oxo-1H-pyridine-3-carbonyl)piperidin-2-yl]-6-ethyl-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C22H27N5O3
    2-[(2S)-1-(5,6-dimethyl-2-oxo-1H-pyridine-3-carbonyl)piperidin-2-yl]-6-ethyl-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5,6-dimethyl-2-[(2R)-1-(3-methyl-1,2-oxazole-5-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H21N5O3
    5,6-dimethyl-2-[(2R)-1-(3-methyl-1,2-oxazole-5-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2S)-1-[(3S)-oxolane-3-carbonyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H26N4O3
    6-ethyl-5-methyl-2-[(2S)-1-[(3S)-oxolane-3-carbonyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2R)-1-(pyridine-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H23N5O2
    6-ethyl-5-methyl-2-[(2R)-1-(pyridine-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(2S)-1-(2,4-dimethyl-1,3-oxazole-5-carbonyl)piperidin-2-yl]-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H21N5O3
    2-[(2S)-1-(2,4-dimethyl-1,3-oxazole-5-carbonyl)piperidin-2-yl]-5-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-tert-butyl-5-[(3S)-1-(2-methoxypyrimidine-5-carbonyl)pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H24N6O3
    2-tert-butyl-5-[(3S)-1-(2-methoxypyrimidine-5-carbonyl)pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5-[(3S)-1-[4-(methoxymethyl)benzoyl]pyrrolidin-3-yl]-2-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H22N4O3
    5-[(3S)-1-[4-(methoxymethyl)benzoyl]pyrrolidin-3-yl]-2-methyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-fluoro-5-methyl-2-[(2S)-1-[2-(3-methyl-6-oxopyridazin-1-yl)acetyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H21FN6O3
    6-fluoro-5-methyl-2-[(2S)-1-[2-(3-methyl-6-oxopyridazin-1-yl)acetyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5-methyl-2-[(2S)-1-(4-methyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C17H19N5O2S
    5-methyl-2-[(2S)-1-(4-methyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2S)-1-(4-methylthiadiazole-5-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H22N6O2S
    6-ethyl-5-methyl-2-[(2S)-1-(4-methylthiadiazole-5-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2R)-1-[(3R)-oxolane-3-carbonyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H26N4O3
    6-ethyl-5-methyl-2-[(2R)-1-[(3R)-oxolane-3-carbonyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(2R)-1-(5-ethyl-1,2-oxazole-3-carbonyl)piperidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H23N5O3
    2-[(2R)-1-(5-ethyl-1,2-oxazole-3-carbonyl)piperidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2S)-1-(pyridine-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H23N5O2
    6-ethyl-5-methyl-2-[(2S)-1-(pyridine-3-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(2R)-1-(2-methoxypyridine-4-carbonyl)piperidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H23N5O3
    2-[(2R)-1-(2-methoxypyridine-4-carbonyl)piperidin-2-yl]-5,6-dimethyl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2S)-1-(5-methylpyrazine-2-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H24N6O2
    6-ethyl-5-methyl-2-[(2S)-1-(5-methylpyrazine-2-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-tert-butyl-5-[(3R)-1-(2-methoxypyrimidine-5-carbonyl)pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H24N6O3
    2-tert-butyl-5-[(3R)-1-(2-methoxypyrimidine-5-carbonyl)pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2S)-1-(1,3-thiazole-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H21N5O2S
    6-ethyl-5-methyl-2-[(2S)-1-(1,3-thiazole-4-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5,6-dimethyl-2-[(2R)-1-(4-methyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H21N5O2S
    5,6-dimethyl-2-[(2R)-1-(4-methyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5,6-dimethyl-2-[(2S)-1-(4-methyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C18H21N5O2S
    5,6-dimethyl-2-[(2S)-1-(4-methyl-1,3-thiazole-5-carbonyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2R)-1-[4-(2-oxopyrrolidin-1-yl)butanoyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C22H31N5O3
    6-ethyl-5-methyl-2-[(2R)-1-[4-(2-oxopyrrolidin-1-yl)butanoyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-tert-butyl-5-[(3R)-1-(2,4-dimethyl-1,3-oxazole-5-carbonyl)pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H25N5O3
    2-tert-butyl-5-[(3R)-1-(2,4-dimethyl-1,3-oxazole-5-carbonyl)pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-fluoro-5-methyl-2-[(2R)-1-[2-(3-methyl-6-oxopyridazin-1-yl)acetyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H21FN6O3
    6-fluoro-5-methyl-2-[(2R)-1-[2-(3-methyl-6-oxopyridazin-1-yl)acetyl]piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one