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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— [(1S,2R)-2-methylcyclopropyl]-[(2R)-2-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C21H21F3N4OS
    [(1S,2R)-2-methylcyclopropyl]-[(2R)-2-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2S)-2-methylcyclopropyl]methanone —— C21H32F2N4O
    [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2S)-2-methylcyclopropyl]methanone
    —— [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2S)-2-methylcyclopropyl]methanone —— C21H32F2N4O
    [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2S)-2-methylcyclopropyl]methanone
    —— [4-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2R)-2-methylcyclopropyl]methanone —— C21H31F3N4O
    [4-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2R)-2-methylcyclopropyl]methanone
    —— 1-[(3R)-3-[(5S,7S)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-2-ylethanone —— C20H24F3N5O
    1-[(3R)-3-[(5S,7S)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-2-ylethanone
    —— [4-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2S)-2-methylcyclopropyl]methanone —— C21H31F3N4O
    [4-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2S)-2-methylcyclopropyl]methanone
    —— [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2R)-2-methylcyclopropyl]methanone —— C21H32F2N4O
    [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1R,2R)-2-methylcyclopropyl]methanone
    —— (4R)-4-[(3R)-3-[(5S,7S)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbonyl]-1-propan-2-ylpyrrolidin-2-one —— C21H30F3N5O2
    (4R)-4-[(3R)-3-[(5S,7S)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbonyl]-1-propan-2-ylpyrrolidin-2-one
    —— 1-[(3R)-3-[(5S,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-2-ylethanone —— C20H24F3N5O
    1-[(3R)-3-[(5S,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-2-ylethanone
    —— 2-[(3R)-1,1-dioxothiolan-3-yl]-1-[(3R)-3-[(5S,7S)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone —— C19H27F3N4O3S
    2-[(3R)-1,1-dioxothiolan-3-yl]-1-[(3R)-3-[(5S,7S)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone
    —— [4-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2R)-2-methylcyclopropyl]methanone —— C21H31F3N4O
    [4-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2R)-2-methylcyclopropyl]methanone
    —— [4-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2S)-2-methylcyclopropyl]methanone —— C21H31F3N4O
    [4-[(5S,7R)-2-tert-butyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2S)-2-methylcyclopropyl]methanone
    —— 1-[(3R)-3-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-2-ylethanone —— C20H24F3N5O
    1-[(3R)-3-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-2-ylethanone
    —— 2-[(3R)-1,1-dioxothiolan-3-yl]-1-[(3R)-3-[(5R,7S)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone —— C19H27F3N4O3S
    2-[(3R)-1,1-dioxothiolan-3-yl]-1-[(3R)-3-[(5R,7S)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone
    —— [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2R)-2-methylcyclopropyl]methanone —— C21H32F2N4O
    [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-[(1S,2R)-2-methylcyclopropyl]methanone
    —— 2-[(3R)-1,1-dioxothiolan-3-yl]-1-[(3R)-3-[(5S,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone —— C19H27F3N4O3S
    2-[(3R)-1,1-dioxothiolan-3-yl]-1-[(3R)-3-[(5S,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone
    —— 2-[(3R)-1,1-dioxothiolan-3-yl]-1-[(3R)-3-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone —— C19H27F3N4O3S
    2-[(3R)-1,1-dioxothiolan-3-yl]-1-[(3R)-3-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]ethanone
    —— 1-[(3R)-3-[(5R,7S)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-2-ylethanone —— C20H24F3N5O
    1-[(3R)-3-[(5R,7S)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-2-ylethanone
    —— 2-[(2R)-1-[(1R)-1-pyridin-4-ylethyl]pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C22H20F3N5S
    2-[(2R)-1-[(1R)-1-pyridin-4-ylethyl]pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(2R)-1-[(1S)-1-pyridin-4-ylethyl]pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C22H20F3N5S
    2-[(2R)-1-[(1S)-1-pyridin-4-ylethyl]pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-[(1S)-1-imidazol-1-ylethyl]-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C16H14N6O
    5-[(1S)-1-imidazol-1-ylethyl]-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5-[(1R)-1-imidazol-1-ylethyl]-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C16H14N6O
    5-[(1R)-1-imidazol-1-ylethyl]-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5-[(2R)-2-(benzimidazol-1-yl)propyl]-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C21H18N6O
    5-[(2R)-2-(benzimidazol-1-yl)propyl]-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5-[(2S)-2-(benzimidazol-1-yl)propyl]-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C21H18N6O
    5-[(2S)-2-(benzimidazol-1-yl)propyl]-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-tert-butyl-7-ethyl-N-(2-methoxyethyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide —— C16H24N4O2
    2-tert-butyl-7-ethyl-N-(2-methoxyethyl)pyrazolo[1,5-a]pyrimidine-6-carboxamide
    —— 5-cyclopropyl-N-[(2R)-4-morpholin-4-ylbutan-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide —— C19H24F3N5O2
    5-cyclopropyl-N-[(2R)-4-morpholin-4-ylbutan-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
    —— 5-cyclopropyl-N-[(2S)-4-morpholin-4-ylbutan-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide —— C19H24F3N5O2
    5-cyclopropyl-N-[(2S)-4-morpholin-4-ylbutan-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
    —— [(3R)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone —— C23H33F2N5O2
    [(3R)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone
    —— [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone —— C23H33F2N5O2
    [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone
    —— 2-[(3R)-1-[(2-methoxypyrimidin-5-yl)methyl]piperidin-3-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H25F3N6O
    2-[(3R)-1-[(2-methoxypyrimidin-5-yl)methyl]piperidin-3-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(2R)-oxolan-2-yl]-1-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C20H25F3N4O2
    2-[(2R)-oxolan-2-yl]-1-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— 1-methyl-4-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyridin-2-one —— C21H22F3N5O2
    1-methyl-4-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyridin-2-one
    —— 5-propan-2-yl-2-[(2R)-1-(pyridin-2-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H22F3N5
    5-propan-2-yl-2-[(2R)-1-(pyridin-2-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-propan-2-yl-2-[(2S)-1-(pyridin-3-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H22F3N5
    5-propan-2-yl-2-[(2S)-1-(pyridin-3-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— [2-(dimethylamino)pyrimidin-5-yl]-[(3S)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C21H24F3N7O
    [2-(dimethylamino)pyrimidin-5-yl]-[(3S)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 1-methyl-4-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyridin-2-one —— C21H22F3N5O2
    1-methyl-4-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyridin-2-one
    —— 5-propan-2-yl-2-[(2S)-1-[(1S)-1-pyridin-4-ylethyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H24F3N5
    5-propan-2-yl-2-[(2S)-1-[(1S)-1-pyridin-4-ylethyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-propan-2-yl-2-[(2S)-1-(thian-4-yl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H25F3N4S
    5-propan-2-yl-2-[(2S)-1-(thian-4-yl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— [(3S)-1,1-dioxothiolan-3-yl]-[(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H23F3N4O3S
    [(3S)-1,1-dioxothiolan-3-yl]-[(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 5-propan-2-yl-2-[(2R)-1-(thian-4-yl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H25F3N4S
    5-propan-2-yl-2-[(2R)-1-(thian-4-yl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-propan-2-yl-2-[(3R)-1-(pyridin-4-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H24F3N5
    5-propan-2-yl-2-[(3R)-1-(pyridin-4-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-(Oxan-4-yl)-5-propan-2-yl-7-prop-2-enoxypyrazolo[1,5-a]pyrimidine —— C17H23N3O2
    2-(Oxan-4-yl)-5-propan-2-yl-7-prop-2-enoxypyrazolo[1,5-a]pyrimidine
    —— [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone —— C23H33F2N5O2
    [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone
    —— (1-propan-2-ylpyrazol-4-yl)-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C21H25F3N6O
    (1-propan-2-ylpyrazol-4-yl)-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 2-[(2S)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-2-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H25F3N4O
    2-[(2S)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-2-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-propan-2-yl-2-[(2S)-1-(pyridin-2-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H22F3N5
    5-propan-2-yl-2-[(2S)-1-(pyridin-2-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-propan-2-yl-2-[(3S)-1-(pyridin-4-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H24F3N5
    5-propan-2-yl-2-[(3S)-1-(pyridin-4-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-(1-methylpiperidin-4-ylidene)-1-[(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C22H28F3N5O
    2-(1-methylpiperidin-4-ylidene)-1-[(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— 5-propan-2-yl-2-[(2R)-1-[(1S)-1-pyridin-4-ylethyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H24F3N5
    5-propan-2-yl-2-[(2R)-1-[(1S)-1-pyridin-4-ylethyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-propan-2-yl-2-[(3R)-1-(pyridin-3-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H24F3N5
    5-propan-2-yl-2-[(3R)-1-(pyridin-3-ylmethyl)piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine