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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (4-methyl-1,2,5-oxadiazol-3-yl)-[(2R)-2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C17H17F3N6O2
    (4-methyl-1,2,5-oxadiazol-3-yl)-[(2R)-2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— (4R)-4-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]-1-methylpyrrolidin-2-one —— C19H22F3N5O2
    (4R)-4-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]-1-methylpyrrolidin-2-one
    —— [(2R)-2-[5-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1,3-thiazol-4-yl)methanone —— C20H22F3N5OS
    [(2R)-2-[5-tert-butyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1,3-thiazol-4-yl)methanone
    —— 1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-methoxyethanone —— C16H19F3N4O2
    1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-methoxyethanone
    —— 2-methyl-1-[(2R)-2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one —— C16H19F3N4O
    2-methyl-1-[(2R)-2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one
    —— [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(4-methylthiadiazol-5-yl)methanone —— C18H19F3N6OS
    [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(4-methylthiadiazol-5-yl)methanone
    —— (4-methylthiadiazol-5-yl)-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C18H19F3N6OS
    (4-methylthiadiazol-5-yl)-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (3S)-3-(3,5-dimethylpyrazol-1-yl)-1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]butan-1-one —— C22H27F3N6O
    (3S)-3-(3,5-dimethylpyrazol-1-yl)-1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]butan-1-one
    —— (5-methylpyrazin-2-yl)-[(2S)-2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C19H19F3N6O
    (5-methylpyrazin-2-yl)-[(2S)-2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— (2S)-3-(3,5-dimethylpyrazol-1-yl)-2-methyl-1-[(2S)-2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one —— C21H25F3N6O
    (2S)-3-(3,5-dimethylpyrazol-1-yl)-2-methyl-1-[(2S)-2-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one
    —— [(1R)-cyclohex-3-en-1-yl]-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C21H25F3N4O
    [(1R)-cyclohex-3-en-1-yl]-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(3-propan-2-yl-1,2-oxazol-5-yl)methanone —— C21H24F3N5O2
    [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(3-propan-2-yl-1,2-oxazol-5-yl)methanone
    —— [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(5-methylpyrazin-2-yl)methanone —— C20H21F3N6O
    [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(5-methylpyrazin-2-yl)methanone
    —— 1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-(3,4,5-trimethylpyrazol-1-yl)ethanone —— C21H25F3N6O
    1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-(3,4,5-trimethylpyrazol-1-yl)ethanone
    —— (1,3-dimethylpyrazol-4-yl)-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H23F3N6O
    (1,3-dimethylpyrazol-4-yl)-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 2-(4-methylpyrazol-1-yl)-1-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C20H23F3N6O
    2-(4-methylpyrazol-1-yl)-1-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— 2-(4-methylpyrazol-1-yl)-1-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C20H23F3N6O
    2-(4-methylpyrazol-1-yl)-1-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— 5-methyl-2-[(2R)-1-(pyridin-4-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C18H18F3N5
    5-methyl-2-[(2R)-1-(pyridin-4-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (4R)-1-methyl-4-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyrrolidin-2-one —— C20H24F3N5O2
    (4R)-1-methyl-4-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyrrolidin-2-one
    —— cyclopentyl-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C20H25F3N4O
    cyclopentyl-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [(3R)-1,1-dioxothiolan-3-yl]-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H23F3N4O3S
    [(3R)-1,1-dioxothiolan-3-yl]-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 5,6-dimethyl-2-[(2R)-1-(2-pyridin-2-ylacetyl)pyrrolidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H21N5O2
    5,6-dimethyl-2-[(2R)-1-(2-pyridin-2-ylacetyl)pyrrolidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(2S)-1-[[3-(2-methoxyethoxy)phenyl]methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C22H25F3N4O2
    2-[(2S)-1-[[3-(2-methoxyethoxy)phenyl]methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (4S)-4-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbonyl]-1-prop-2-enylpyrrolidin-2-one —— C22H26F3N5O2
    (4S)-4-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbonyl]-1-prop-2-enylpyrrolidin-2-one
    —— 1-methyl-5-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyridin-2-one —— C21H22F3N5O2
    1-methyl-5-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyridin-2-one
    —— (3Z)-2-amino-3-[(2,5-dimethylphenyl)hydrazinylidene]-7-methylpyrazolo[1,5-a]pyrimidin-5-one —— C15H16N6O
    (3Z)-2-amino-3-[(2,5-dimethylphenyl)hydrazinylidene]-7-methylpyrazolo[1,5-a]pyrimidin-5-one
    —— 5-methyl-2-[(2S)-1-(2-pyridin-2-ylacetyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H21N5O2
    5-methyl-2-[(2S)-1-(2-pyridin-2-ylacetyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(2S)-1-(2-pyridin-2-ylacetyl)pyrrolidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H23N5O2
    6-ethyl-5-methyl-2-[(2S)-1-(2-pyridin-2-ylacetyl)pyrrolidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 6-ethyl-5-methyl-2-[(3R)-1-(pyridin-4-ylmethyl)pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H23N5O
    6-ethyl-5-methyl-2-[(3R)-1-(pyridin-4-ylmethyl)pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— [(3S)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1H-pyrazol-5-yl)methanone —— C17H17F3N6O
    [(3S)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1H-pyrazol-5-yl)methanone
    —— 6-ethyl-5-methyl-2-[(2R)-1-(2-pyridin-2-ylacetyl)pyrrolidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H23N5O2
    6-ethyl-5-methyl-2-[(2R)-1-(2-pyridin-2-ylacetyl)pyrrolidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5-ethyl-2-[(3S)-1-[(6-methylpyridin-2-yl)methyl]pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C19H23N5O
    5-ethyl-2-[(3S)-1-[(6-methylpyridin-2-yl)methyl]pyrrolidin-3-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5-ethyl-2-[(2R)-1-(2-pyridin-2-ylacetyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C20H23N5O2
    5-ethyl-2-[(2R)-1-(2-pyridin-2-ylacetyl)piperidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 5,6-dimethyl-2-[(2R)-1-(5-methyl-1H-pyrazole-4-carbonyl)pyrrolidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C17H20N6O2
    5,6-dimethyl-2-[(2R)-1-(5-methyl-1H-pyrazole-4-carbonyl)pyrrolidin-2-yl]-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— (6-fluoro-1H-benzimidazol-2-yl)-[(3R)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C21H18F4N6O
    (6-fluoro-1H-benzimidazol-2-yl)-[(3R)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 5-Ethyl-2-[1-[(3-ethylimidazol-4-yl)methyl]piperidin-4-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H25F3N6
    5-Ethyl-2-[1-[(3-ethylimidazol-4-yl)methyl]piperidin-4-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (3S)-1-[(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-imidazol-1-ylbutan-1-one —— C20H23F3N6O
    (3S)-1-[(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-imidazol-1-ylbutan-1-one
    —— 3-methoxy-1-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one —— C18H23F3N4O2
    3-methoxy-1-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one
    —— [(2R)-oxolan-2-yl]-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H23F3N4O2
    [(2R)-oxolan-2-yl]-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 2-propan-2-yl-N-[2-(5-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-2-yl)ethyl]pyrazole-3-carboxamide —— C20H21N7O
    2-propan-2-yl-N-[2-(5-pyridin-4-ylpyrazolo[1,5-a]pyrimidin-2-yl)ethyl]pyrazole-3-carboxamide
    —— 1-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyrazol-1-ylethanone —— C19H21F3N6O
    1-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyrazol-1-ylethanone
    —— [(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-pyridin-4-ylmethanone —— C21H22F3N5O
    [(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-pyridin-4-ylmethanone
    —— 2-[(3S)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-3-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H25F3N4O
    2-[(3S)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-3-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (2-methylpyrazol-3-yl)-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H21F3N6O
    (2-methylpyrazol-3-yl)-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(2S)-oxolan-2-yl]-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H23F3N4O2
    [(2S)-oxolan-2-yl]-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyrimidin-5-ylmethanone —— C19H19F3N6O
    [(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyrimidin-5-ylmethanone
    —— [(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyridin-2-ylmethanone —— C20H20F3N5O
    [(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyridin-2-ylmethanone
    —— 2-methoxy-1-[(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C17H21F3N4O2
    2-methoxy-1-[(3R)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— 2-methoxy-1-[(2R)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C17H25F3N4O2
    2-methoxy-1-[(2R)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— [(3S)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-pyridin-3-ylmethanone —— C21H22F3N5O
    [(3S)-3-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-pyridin-3-ylmethanone