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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-ethyl-3-methyl-1,2-oxazol-4-yl)methanone —— C23H33F2N5O2
    [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-ethyl-3-methyl-1,2-oxazol-4-yl)methanone
    —— [(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(4-methoxycyclohexyl)methanone —— C22H33F3N4O2
    [(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(4-methoxycyclohexyl)methanone
    —— cyclopropyl-[(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C17H23F3N4O
    cyclopropyl-[(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 1-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-[(2S)-oxolan-2-yl]propan-1-one —— C20H29F3N4O2
    1-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-[(2S)-oxolan-2-yl]propan-1-one
    —— [(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(5-methylpyrazin-2-yl)methanone —— C20H25F3N6O
    [(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(5-methylpyrazin-2-yl)methanone
    —— 1-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone —— C18H23F3N6O2
    1-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone
    —— (1,5-dimethylpyrazol-4-yl)-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H25F3N6O
    (1,5-dimethylpyrazol-4-yl)-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [2-(dimethylamino)pyridin-4-yl]-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C21H27F3N6O
    [2-(dimethylamino)pyridin-4-yl]-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (5S,7S)-5-ethyl-N-[(2S)-2-morpholin-4-ylpropyl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C17H26F3N5O2
    (5S,7S)-5-ethyl-N-[(2S)-2-morpholin-4-ylpropyl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide
    —— [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methyl-5-propan-2-ylpyrazol-3-yl)methanone —— C21H29F3N6O
    [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methyl-5-propan-2-ylpyrazol-3-yl)methanone
    —— 1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyridin-3-yloxyethanone —— C20H24F3N5O2
    1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyridin-3-yloxyethanone
    —— 4-[(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbonyl]-1-methylpyridin-2-one —— C21H26F3N5O2
    4-[(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidine-1-carbonyl]-1-methylpyridin-2-one
    —— [4-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1H-pyrazol-5-yl)methanone —— C18H23F3N6O
    [4-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1H-pyrazol-5-yl)methanone
    —— 1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone —— C18H23F3N6O2
    1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone
    —— [(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone —— C20H26F3N5O2
    [(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone
    —— [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(5-propan-2-yl-1H-pyrazol-3-yl)methanone —— C20H27F3N6O
    [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(5-propan-2-yl-1H-pyrazol-3-yl)methanone
    —— 1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-(3,4,5-trimethylpyrazol-1-yl)ethanone —— C21H29F3N6O
    1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-(3,4,5-trimethylpyrazol-1-yl)ethanone
    —— [(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methyl-5-propan-2-ylpyrazol-3-yl)methanone —— C21H29F3N6O
    [(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methyl-5-propan-2-ylpyrazol-3-yl)methanone
    —— [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(5-methylpyrazin-2-yl)methanone —— C19H23F3N6O
    [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(5-methylpyrazin-2-yl)methanone
    —— [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-methylpyridin-4-yl)methanone —— C20H24F3N5O
    [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-methylpyridin-4-yl)methanone
    —— [(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-methylpyridin-4-yl)methanone —— C20H24F3N5O
    [(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-methylpyridin-4-yl)methanone
    —— [(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone —— C18H22F3N5O2
    [(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone
    —— [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1-propan-2-ylpyrazol-4-yl)methanone —— C20H27F3N6O
    [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1-propan-2-ylpyrazol-4-yl)methanone
    —— [(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-[(2R)-oxolan-2-yl]methanone —— C18H25F3N4O2
    [(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-[(2R)-oxolan-2-yl]methanone
    —— 1-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyridin-3-ylpropan-1-one —— C21H26F3N5O
    1-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyridin-3-ylpropan-1-one
    —— [(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-propan-2-yl-1,2-oxazol-5-yl)methanone —— C20H26F3N5O2
    [(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-propan-2-yl-1,2-oxazol-5-yl)methanone
    —— 1-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-[(2R)-oxolan-2-yl]ethanone —— C19H27F3N4O2
    1-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-[(2R)-oxolan-2-yl]ethanone
    —— [(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-propan-2-yl-1,2-oxazol-5-yl)methanone —— C20H26F3N5O2
    [(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-propan-2-yl-1,2-oxazol-5-yl)methanone
    —— [(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1-methylpyrazol-4-yl)methanone —— C18H23F3N6O
    [(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1-methylpyrazol-4-yl)methanone
    —— (5R,7R)-5-ethyl-2-[(3S)-1-pyrrolidin-1-ylsulfonylpyrrolidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C17H26F3N5O2S
    (5R,7R)-5-ethyl-2-[(3S)-1-pyrrolidin-1-ylsulfonylpyrrolidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— [4-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1-methylpyrazol-4-yl)methanone —— C19H25F3N6O
    [4-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1-methylpyrazol-4-yl)methanone
    —— (1,3-dimethylpyrazol-4-yl)-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H25F3N6O
    (1,3-dimethylpyrazol-4-yl)-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyridin-2-ylethanone —— C20H24F3N5O
    1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyridin-2-ylethanone
    —— cyclopropyl-[(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C17H23F3N4O
    cyclopropyl-[(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylpropan-1-one —— C19H25F3N6O
    1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylpropan-1-one
    —— (3,5-dimethyl-1,2-oxazol-4-yl)-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H24F3N5O2
    (3,5-dimethyl-1,2-oxazol-4-yl)-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methoxypyridin-4-yl)methanone —— C20H24F3N5O2
    [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methoxypyridin-4-yl)methanone
    —— (3,5-dimethyl-1,2-oxazol-4-yl)-[(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H24F3N5O2
    (3,5-dimethyl-1,2-oxazol-4-yl)-[(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1,3-thiazol-4-yl)methanone —— C18H22F3N5OS
    [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1,3-thiazol-4-yl)methanone
    —— [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1,3-thiazol-4-yl)methanone —— C17H20F3N5OS
    [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1,3-thiazol-4-yl)methanone
    —— 2-[2-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-6-methylpyridazin-3-one —— C20H25F3N6O2
    2-[2-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-6-methylpyridazin-3-one
    —— [(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methylpyridin-3-yl)methanone —— C20H24F3N5O
    [(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methylpyridin-3-yl)methanone
    —— [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone —— C20H26F3N5O2
    [(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone
    —— 3-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]-4,6-dimethyl-1H-pyridin-2-one —— C21H26F3N5O2
    3-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]-4,6-dimethyl-1H-pyridin-2-one
    —— (2,4-dimethyl-1,3-oxazol-5-yl)-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H24F3N5O2
    (2,4-dimethyl-1,3-oxazol-5-yl)-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (5R,7R)-5-ethyl-2-[(3R)-1-pyrrolidin-1-ylsulfonylpyrrolidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C17H26F3N5O2S
    (5R,7R)-5-ethyl-2-[(3R)-1-pyrrolidin-1-ylsulfonylpyrrolidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— 1-[4-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-4-oxobutyl]pyrrolidin-2-one —— C21H30F3N5O2
    1-[4-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-4-oxobutyl]pyrrolidin-2-one
    —— cyclopropyl-[(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C18H25F3N4O
    cyclopropyl-[(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-[(2S)-oxolan-2-yl]propan-1-one —— C20H29F3N4O2
    1-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-[(2S)-oxolan-2-yl]propan-1-one
    —— (5S,7S)-5-ethyl-N-[(2S)-2-(4-methylpiperidin-1-yl)propyl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide —— C19H30F3N5O
    (5S,7S)-5-ethyl-N-[(2S)-2-(4-methylpiperidin-1-yl)propyl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide