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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (5-ethyl-1,2-oxazol-3-yl)-[(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H24F3N5O2
    (5-ethyl-1,2-oxazol-3-yl)-[(3S)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 5-Tert-butyl-2-[1-[(2-ethylpyrimidin-5-yl)methyl]piperidin-4-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C23H29F3N6
    5-Tert-butyl-2-[1-[(2-ethylpyrimidin-5-yl)methyl]piperidin-4-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(2R)-1-[(2-ethylpyrimidin-5-yl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H21F3N6
    2-[(2R)-1-[(2-ethylpyrimidin-5-yl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— [5-[[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methyl]-2-methoxyphenyl]methanol —— C22H25F3N4O2
    [5-[[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methyl]-2-methoxyphenyl]methanol
    —— 5-[(3R)-1-[(5-ethylfuran-2-yl)methyl]piperidin-3-yl]-2-methylpyrazolo[1,5-a]pyrimidin-7-amine —— C19H25N5O
    5-[(3R)-1-[(5-ethylfuran-2-yl)methyl]piperidin-3-yl]-2-methylpyrazolo[1,5-a]pyrimidin-7-amine
    —— (5R,7R)-2-[(3S)-1-(1-ethyl-3-methylpyrazol-4-yl)sulfonylpyrrolidin-3-yl]-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C18H25F3N6O2S
    (5R,7R)-2-[(3S)-1-(1-ethyl-3-methylpyrazol-4-yl)sulfonylpyrrolidin-3-yl]-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— (3-ethyl-1,2-oxazol-5-yl)-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H24F3N5O2
    (3-ethyl-1,2-oxazol-5-yl)-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (5-ethyl-1,2-oxazol-3-yl)-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C20H26F3N5O2
    (5-ethyl-1,2-oxazol-3-yl)-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [(1S)-cyclohex-3-en-1-yl]-[(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H23F3N4O
    [(1S)-cyclohex-3-en-1-yl]-[(3S)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyrimidin-5-ylmethanone —— C18H17F3N6O
    [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyrimidin-5-ylmethanone
    —— [(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methoxypyrimidin-5-yl)methanone —— C19H19F3N6O2
    [(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methoxypyrimidin-5-yl)methanone
    —— [(1S)-cyclohex-3-en-1-yl]-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H23F3N4O
    [(1S)-cyclohex-3-en-1-yl]-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 5-ethyl-2-[(2R)-1-[(1S)-1-pyridin-4-ylethyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H22F3N5
    5-ethyl-2-[(2R)-1-[(1S)-1-pyridin-4-ylethyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(3S)-1-[(3-ethoxy-4-methoxyphenyl)methyl]pyrrolidin-3-yl]-5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C23H27F3N4O2
    2-[(3S)-1-[(3-ethoxy-4-methoxyphenyl)methyl]pyrrolidin-3-yl]-5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-ethyl-2-[(2R)-1-(pyridin-3-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H20F3N5
    5-ethyl-2-[(2R)-1-(pyridin-3-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-ethyl-2-[(3S)-1-[(2-methylpyrimidin-5-yl)methyl]piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H23F3N6
    5-ethyl-2-[(3S)-1-[(2-methylpyrimidin-5-yl)methyl]piperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (2-methyl-5-propylpyrazol-3-yl)-[(3S)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H23F3N6O
    (2-methyl-5-propylpyrazol-3-yl)-[(3S)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (4R)-4-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]-1-propan-2-ylpyrrolidin-2-one —— C21H26F3N5O2
    (4R)-4-[(3R)-3-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]-1-propan-2-ylpyrrolidin-2-one
    —— [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone —— C18H18F3N5O2
    [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone
    —— N-[[(2S)-1,4-dioxan-2-yl]methyl]-6-ethyl-5-methyl-2-(oxan-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine —— C19H28N4O3
    N-[[(2S)-1,4-dioxan-2-yl]methyl]-6-ethyl-5-methyl-2-(oxan-4-yl)pyrazolo[1,5-a]pyrimidin-7-amine
    —— [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyrimidin-5-ylmethanone —— C18H17F3N6O
    [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyrimidin-5-ylmethanone
    —— 2-ethyl-3-methyl-5-pyridin-4-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C14H14N4O
    2-ethyl-3-methyl-5-pyridin-4-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone —— C18H19F3N6O2
    1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-(4-methyl-1,2,5-oxadiazol-3-yl)ethanone
    —— [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone —— C18H18F3N5O2
    [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(3-methyl-1,2-oxazol-5-yl)methanone
    —— 5-ethyl-2-[(2R)-1-(pyridin-4-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C19H20F3N5
    5-ethyl-2-[(2R)-1-(pyridin-4-ylmethyl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (3R)-1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylbutan-1-one —— C20H23F3N6O
    (3R)-1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylbutan-1-one
    —— (3S)-1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylbutan-1-one —— C20H23F3N6O
    (3S)-1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylbutan-1-one
    —— [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methyl-5-propan-2-ylpyrazol-3-yl)methanone —— C21H25F3N6O
    [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(2-methyl-5-propan-2-ylpyrazol-3-yl)methanone
    —— (3-ethyl-1,2-oxazol-5-yl)-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H22F3N5O2
    (3-ethyl-1,2-oxazol-5-yl)-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 5-ethyl-2-[(3R)-1-propan-2-ylsulfonylpiperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C17H23F3N4O2S
    5-ethyl-2-[(3R)-1-propan-2-ylsulfonylpiperidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-ethyl-2-[(2R)-1-[[3-(2-methoxyethoxy)phenyl]methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C23H27F3N4O2
    5-ethyl-2-[(2R)-1-[[3-(2-methoxyethoxy)phenyl]methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-ethyl-2-[(2S)-1-(thian-4-yl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C18H23F3N4S
    5-ethyl-2-[(2S)-1-(thian-4-yl)pyrrolidin-2-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1H-pyrazol-5-yl)methanone —— C17H17F3N6O
    [(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(1H-pyrazol-5-yl)methanone
    —— 1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyridin-2-ylethanone —— C20H20F3N5O
    1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-pyridin-2-ylethanone
    —— (3-ethyl-1,2-oxazol-5-yl)-[(3S)-3-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H26F3N5O2
    (3-ethyl-1,2-oxazol-5-yl)-[(3S)-3-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(4-methyl-1,3-thiazol-5-yl)methanone —— C18H18F3N5OS
    [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(4-methyl-1,3-thiazol-5-yl)methanone
    —— 6-Ethyl-5-methyl-2-(oxan-4-yl)-7-prop-2-ynoxypyrazolo[1,5-a]pyrimidine —— C17H21N3O2
    6-Ethyl-5-methyl-2-(oxan-4-yl)-7-prop-2-ynoxypyrazolo[1,5-a]pyrimidine
    —— [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(3-ethyl-1,2-oxazol-5-yl)methanone —— C22H31F2N5O2
    [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(3-ethyl-1,2-oxazol-5-yl)methanone
    —— 1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-2-ylethanone —— C21H22F3N5O
    1-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-2-ylethanone
    —— (5-ethyl-3-methyl-1,2-oxazol-4-yl)-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C21H28F3N5O2
    (5-ethyl-3-methyl-1,2-oxazol-4-yl)-[(2S)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— (3-ethyl-1,2-oxazol-5-yl)-[(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H24F3N5O2
    (3-ethyl-1,2-oxazol-5-yl)-[(3R)-3-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (1,5-dimethylpyrazol-4-yl)-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H21F3N6O
    (1,5-dimethylpyrazol-4-yl)-[(2S)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone —— C20H22F3N5O2
    [(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-(5-propan-2-yl-1,2-oxazol-3-yl)methanone
    —— (2R)-3-(3,5-dimethylpyrazol-1-yl)-1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-methylpropan-1-one —— C22H27F3N6O
    (2R)-3-(3,5-dimethylpyrazol-1-yl)-1-[(2R)-2-[5-ethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-methylpropan-1-one
    —— [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-ethyl-1,2-oxazol-3-yl)methanone —— C22H31F2N5O2
    [(3S)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-ethyl-1,2-oxazol-3-yl)methanone
    —— (5-ethyl-3-methyl-1,2-oxazol-4-yl)-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H24F3N5O2
    (5-ethyl-3-methyl-1,2-oxazol-4-yl)-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 1-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylpropan-1-one —— C19H25F3N6O
    1-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylpropan-1-one
    —— 1-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-(3,4,5-trimethylpyrazol-1-yl)ethanone —— C21H29F3N6O
    1-[(2R)-2-[(5R,7R)-5-ethyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-(3,4,5-trimethylpyrazol-1-yl)ethanone
    —— (5S,7R)-5-tert-butyl-2-[(2R)-1-ethylsulfonylpiperidin-2-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C18H29F3N4O2S
    (5S,7R)-5-tert-butyl-2-[(2R)-1-ethylsulfonylpiperidin-2-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— (5R,7R)-5-ethyl-2-[(3R)-1-[(2-methylpyrimidin-5-yl)methyl]piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C20H27F3N6
    (5R,7R)-5-ethyl-2-[(3R)-1-[(2-methylpyrimidin-5-yl)methyl]piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine