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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (3R)-1-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylbutan-1-one —— C19H25F3N6O
    (3R)-1-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylbutan-1-one
    —— [(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyridin-2-ylmethanone —— C18H20F3N5O
    [(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyridin-2-ylmethanone
    —— (2-methoxypyridin-4-yl)-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C20H24F3N5O2
    (2-methoxypyridin-4-yl)-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— (5-tert-butyl-1H-pyrazol-3-yl)-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C21H29F3N6O
    (5-tert-butyl-1H-pyrazol-3-yl)-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 1-[(3S)-3-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-3-yloxyethanone —— C20H24F3N5O2
    1-[(3S)-3-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-2-pyridin-3-yloxyethanone
    —— [(3R)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-methylthiophen-3-yl)methanone —— C22H30F2N4OS
    [(3R)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-methylthiophen-3-yl)methanone
    —— (5R,7R)-5-methyl-2-[(2S)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C17H25F3N4O
    (5R,7R)-5-methyl-2-[(2S)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-2-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— 2-methoxy-1-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C15H21F3N4O2
    2-methoxy-1-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— 1-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-[(2S)-oxolan-2-yl]ethanone —— C18H25F3N4O2
    1-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-2-[(2S)-oxolan-2-yl]ethanone
    —— [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-methylthiophen-3-yl)methanone —— C22H30F2N4OS
    [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(5-methylthiophen-3-yl)methanone
    —— (4-methylthiadiazol-5-yl)-[(3R)-3-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C16H19F3N6OS
    (4-methylthiadiazol-5-yl)-[(3R)-3-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (4-methylthiadiazol-5-yl)-[(3R)-3-[(5R,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C19H25F3N6OS
    (4-methylthiadiazol-5-yl)-[(3R)-3-[(5R,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4-methyl-1,3-thiazol-5-yl)methanone —— C21H29F2N5OS
    [4-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(4-methyl-1,3-thiazol-5-yl)methanone
    —— (2,4-dimethyl-1,3-thiazol-5-yl)-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C19H24F3N5OS
    (2,4-dimethyl-1,3-thiazol-5-yl)-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— (2,4-dimethyl-1,3-oxazol-5-yl)-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C18H22F3N5O2
    (2,4-dimethyl-1,3-oxazol-5-yl)-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (2,4-dimethyl-1,3-thiazol-5-yl)-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H22F3N5OS
    (2,4-dimethyl-1,3-thiazol-5-yl)-[(2S)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(2S)-2-(2-tert-butylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-(4-methyl-1,3-thiazol-5-yl)methanone —— C20H25N5OS
    [(2S)-2-(2-tert-butylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-(4-methyl-1,3-thiazol-5-yl)methanone
    —— 1-[(2S)-2-(2-tert-butylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-2-(3,4,5-trimethylpyrazol-1-yl)ethanone —— C23H32N6O
    1-[(2S)-2-(2-tert-butylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-2-(3,4,5-trimethylpyrazol-1-yl)ethanone
    —— (2,4-dimethyl-1,3-oxazol-5-yl)-[(3R)-3-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H26F3N5O2
    (2,4-dimethyl-1,3-oxazol-5-yl)-[(3R)-3-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 2-tert-butyl-7-[(2R)-1-(1,5-dimethylpyrazol-4-yl)sulfonylpyrrolidin-2-yl]pyrazolo[1,5-a]pyrimidine —— C19H26N6O2S
    2-tert-butyl-7-[(2R)-1-(1,5-dimethylpyrazol-4-yl)sulfonylpyrrolidin-2-yl]pyrazolo[1,5-a]pyrimidine
    —— 5,6-Dimethyl-2-(oxan-4-yl)-7-prop-2-ynoxypyrazolo[1,5-a]pyrimidine —— C16H19N3O2
    5,6-Dimethyl-2-(oxan-4-yl)-7-prop-2-ynoxypyrazolo[1,5-a]pyrimidine
    —— (1,5-dimethylpyrazol-4-yl)-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H27F3N6O
    (1,5-dimethylpyrazol-4-yl)-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (2,4-dimethylpyrimidin-5-yl)-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C21H23F3N6O
    (2,4-dimethylpyrimidin-5-yl)-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— (1,5-dimethylpyrazol-4-yl)-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C18H23F3N6O
    (1,5-dimethylpyrazol-4-yl)-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— ethyl (5S,7R)-5-[(3R)-1-[(3S)-oxolane-3-carbonyl]piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate —— C20H27F3N4O4
    ethyl (5S,7R)-5-[(3R)-1-[(3S)-oxolane-3-carbonyl]piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate
    —— ethyl (5S,7R)-5-[1-[(1R,2S)-2-methylcyclopropanecarbonyl]piperidin-4-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate —— C20H27F3N4O3
    ethyl (5S,7R)-5-[1-[(1R,2S)-2-methylcyclopropanecarbonyl]piperidin-4-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate
    —— ethyl (5S,7R)-5-[(3S)-1-[(3R)-oxolane-3-carbonyl]piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate —— C20H27F3N4O4
    ethyl (5S,7R)-5-[(3S)-1-[(3R)-oxolane-3-carbonyl]piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate
    —— ethyl (5S,7R)-5-[(3S)-1-(2-methylpropanoyl)piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate —— C19H27F3N4O3
    ethyl (5S,7R)-5-[(3S)-1-(2-methylpropanoyl)piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate
    —— (2-ethoxypyridin-3-yl)-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone —— C21H26F3N5O2
    (2-ethoxypyridin-3-yl)-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]methanone
    —— ethyl (5S,7R)-5-[(3S)-1-(cyclopropanecarbonyl)piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate —— C19H25F3N4O3
    ethyl (5S,7R)-5-[(3S)-1-(cyclopropanecarbonyl)piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate
    —— (5R,7R)-2-[(2S)-1-[(4-ethoxy-3-methoxyphenyl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C22H29F3N4O2
    (5R,7R)-2-[(2S)-1-[(4-ethoxy-3-methoxyphenyl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— ethyl (5S,7R)-5-[(3R)-1-(cyclopropanecarbonyl)piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate —— C19H25F3N4O3
    ethyl (5S,7R)-5-[(3R)-1-(cyclopropanecarbonyl)piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate
    —— (4R)-1-ethyl-4-[(3S)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyrrolidin-2-one —— C19H22F3N5O2
    (4R)-1-ethyl-4-[(3S)-3-[5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyrrolidin-2-one
    —— ethyl (5S,7R)-5-[(3R)-1-[(2S)-oxolane-2-carbonyl]piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate —— C20H27F3N4O4
    ethyl (5S,7R)-5-[(3R)-1-[(2S)-oxolane-2-carbonyl]piperidin-3-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate
    —— (4R)-4-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-ethylpyrrolidin-2-one —— C20H29F2N5O2
    (4R)-4-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-ethylpyrrolidin-2-one
    —— (4S)-1-ethyl-4-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]pyrrolidin-2-one —— C20H28F3N5O2
    (4S)-1-ethyl-4-[4-[(5S,7R)-2-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]pyrrolidin-2-one
    —— (4S)-4-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-ethylpyrrolidin-2-one —— C20H29F2N5O2
    (4S)-4-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-ethylpyrrolidin-2-one
    —— (4R)-1-ethyl-4-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyrrolidin-2-one —— C19H26F3N5O2
    (4R)-1-ethyl-4-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyrrolidin-2-one
    —— N-[3-(4-ethylpiperazin-1-yl)propyl]-5,6-dimethyl-2-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine —— C21H31N7O
    N-[3-(4-ethylpiperazin-1-yl)propyl]-5,6-dimethyl-2-(5-methyl-1,2-oxazol-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine
    —— 2-methyl-5-[(3S)-1-[(2-propylpyrimidin-5-yl)methyl]piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine —— C20H27N7
    2-methyl-5-[(3S)-1-[(2-propylpyrimidin-5-yl)methyl]piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
    —— 2-[(2R)-1-(1-ethylpyrazol-4-yl)sulfonylpiperidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C18H21F3N6O2S
    2-[(2R)-1-(1-ethylpyrazol-4-yl)sulfonylpiperidin-2-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (4S)-1-ethyl-4-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyrrolidin-2-one —— C19H26F3N5O2
    (4S)-1-ethyl-4-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidine-1-carbonyl]pyrrolidin-2-one
    —— 2-tert-butyl-7-[(2R)-1-(1-ethyl-3-methylpyrazol-4-yl)sulfonylpyrrolidin-2-yl]pyrazolo[1,5-a]pyrimidine —— C20H28N6O2S
    2-tert-butyl-7-[(2R)-1-(1-ethyl-3-methylpyrazol-4-yl)sulfonylpyrrolidin-2-yl]pyrazolo[1,5-a]pyrimidine
    —— (4R)-4-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-ethylpyrrolidin-2-one —— C20H29F2N5O2
    (4R)-4-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-ethylpyrrolidin-2-one
    —— (4R)-4-[4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-ethylpyrrolidin-2-one —— C20H29F2N5O2
    (4R)-4-[4-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidine-1-carbonyl]-1-ethylpyrrolidin-2-one
    —— 2-methyl-5-[(3S)-1-[(5-methyl-1-propylpyrazol-4-yl)methyl]piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine —— C20H29N7
    2-methyl-5-[(3S)-1-[(5-methyl-1-propylpyrazol-4-yl)methyl]piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
    —— 5-ethyl-2-[(3R)-1-[(2-propylpyrimidin-5-yl)methyl]pyrrolidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H25F3N6
    5-ethyl-2-[(3R)-1-[(2-propylpyrimidin-5-yl)methyl]pyrrolidin-3-yl]-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-[(3R)-1-[(2-ethylpyrimidin-5-yl)methyl]piperidin-3-yl]-2-methylpyrazolo[1,5-a]pyrimidin-7-amine —— C19H25N7
    5-[(3R)-1-[(2-ethylpyrimidin-5-yl)methyl]piperidin-3-yl]-2-methylpyrazolo[1,5-a]pyrimidin-7-amine
    —— (3-ethyl-1,2-oxazol-5-yl)-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C20H26F3N5O2
    (3-ethyl-1,2-oxazol-5-yl)-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 2-[(3R)-1-[(2-ethylpyrimidin-5-yl)methyl]piperidin-3-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C22H27F3N6
    2-[(3R)-1-[(2-ethylpyrimidin-5-yl)methyl]piperidin-3-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine