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    首页 分子通 按分子结构分类 有机化合物 有机杂环化合物 吡唑并嘧啶类

    吡唑并嘧啶类

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— cyclopropyl-[4-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone —— C19H27F3N4O
    cyclopropyl-[4-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]methanone
    —— 1-[(2R)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylpropan-1-one —— C20H27F3N6O
    1-[(2R)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-3-pyrazol-1-ylpropan-1-one
    —— [(3S)-1,1-dioxothiolan-3-yl]-[(3R)-3-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H27F3N4O3S
    [(3S)-1,1-dioxothiolan-3-yl]-[(3R)-3-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(2S)-oxolan-2-yl]-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C19H27F3N4O2
    [(2S)-oxolan-2-yl]-[(2S)-2-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 2-(2-fluorophenoxy)-N-[(1S)-2-methyl-1-(7-oxo-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-5-yl)propyl]acetamide —— C23H22FN5O3
    2-(2-fluorophenoxy)-N-[(1S)-2-methyl-1-(7-oxo-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-5-yl)propyl]acetamide
    —— (5S,7R)-5-tert-butyl-2-(1-propan-2-ylsulfonylpiperidin-4-yl)-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C19H31F3N4O2S
    (5S,7R)-5-tert-butyl-2-(1-propan-2-ylsulfonylpiperidin-4-yl)-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— [(3S)-3-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyridin-2-ylmethanone —— C20H24F3N5O
    [(3S)-3-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]-pyridin-2-ylmethanone
    —— 3-(1,2-oxazol-5-yl)-1-[(3S)-3-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one —— C20H26F3N5O2
    3-(1,2-oxazol-5-yl)-1-[(3S)-3-[(5S,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one
    —— [(3R)-3-[(5R,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-pyridin-2-ylmethanone —— C21H26F3N5O
    [(3R)-3-[(5R,7R)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-pyridin-2-ylmethanone
    —— (5S,7R)-5-propan-2-yl-2-[(2R)-1-(pyridin-3-ylmethyl)piperidin-2-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C21H28F3N5
    (5S,7R)-5-propan-2-yl-2-[(2R)-1-(pyridin-3-ylmethyl)piperidin-2-yl]-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— (5S,7R)-2-[(2S)-1-[(1-methylpyrazol-4-yl)methyl]piperidin-2-yl]-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C20H29F3N6
    (5S,7R)-2-[(2S)-1-[(1-methylpyrazol-4-yl)methyl]piperidin-2-yl]-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— [(3R)-3-[(5R,7S)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1H-pyrazol-5-yl)methanone —— C19H25F3N6O
    [(3R)-3-[(5R,7S)-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]piperidin-1-yl]-(1H-pyrazol-5-yl)methanone
    —— 5-[(1S)-1-[(6-methoxy-2,3-dihydro-1H-inden-5-yl)methylamino]-2-methylpropyl]-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C26H29N5O2
    5-[(1S)-1-[(6-methoxy-2,3-dihydro-1H-inden-5-yl)methylamino]-2-methylpropyl]-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— pyridin-4-yl-[(3R)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C21H16F3N5OS
    pyridin-4-yl-[(3R)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— 2-[(3R)-1-(pyrazolo[1,5-a]pyrimidine-2-carbonyl)piperidin-3-yl]-6-thiophen-2-yl-1H-pyrimidin-4-one —— C20H18N6O2S
    2-[(3R)-1-(pyrazolo[1,5-a]pyrimidine-2-carbonyl)piperidin-3-yl]-6-thiophen-2-yl-1H-pyrimidin-4-one
    —— 2-[(2R)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C20H21F3N4OS
    2-[(2R)-1-[[(3S)-oxolan-3-yl]methyl]pyrrolidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(2R)-1-[[(3S)-oxolan-3-yl]methyl]piperidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H23F3N4OS
    2-[(2R)-1-[[(3S)-oxolan-3-yl]methyl]piperidin-2-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-[(3R)-1-(pyridin-4-ylmethyl)pyrrolidin-3-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H18F3N5S
    2-[(3R)-1-(pyridin-4-ylmethyl)pyrrolidin-3-yl]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 5-[(3R)-1-(2,3-dihydro-1,4-dioxin-5-ylmethyl)piperidin-3-yl]-2-(furan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine —— C20H23N5O3
    5-[(3R)-1-(2,3-dihydro-1,4-dioxin-5-ylmethyl)piperidin-3-yl]-2-(furan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
    —— 2-imidazol-1-yl-1-[(3R)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C20H17F3N6OS
    2-imidazol-1-yl-1-[(3R)-3-[5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— N-[(3S)-1,1-dioxothiolan-3-yl]-2-(1-methyl-4-oxopyrazolo[3,4-d]pyrimidin-5-yl)-N-(2-methylpropyl)acetamide —— C16H23N5O4S
    N-[(3S)-1,1-dioxothiolan-3-yl]-2-(1-methyl-4-oxopyrazolo[3,4-d]pyrimidin-5-yl)-N-(2-methylpropyl)acetamide
    —— N-[(2R)-butan-2-yl]-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(1-methyl-4-oxopyrazolo[3,4-d]pyrimidin-5-yl)acetamide —— C16H23N5O4S
    N-[(2R)-butan-2-yl]-N-[(3S)-1,1-dioxothiolan-3-yl]-2-(1-methyl-4-oxopyrazolo[3,4-d]pyrimidin-5-yl)acetamide
    —— 5-(1-methylpyrazol-4-yl)-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C15H12N6O
    5-(1-methylpyrazol-4-yl)-2-pyridin-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2S)-2-(1-methylpyrazol-3-yl)azepan-1-yl]methanone —— C21H24F2N6O
    [5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]-[(2S)-2-(1-methylpyrazol-3-yl)azepan-1-yl]methanone
    —— [(2S)-2-(4-chloro-2-methylpyrazol-3-yl)azepan-1-yl]-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone —— C21H23ClF2N6O
    [(2S)-2-(4-chloro-2-methylpyrazol-3-yl)azepan-1-yl]-[5-cyclopropyl-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]methanone
    —— 2-[(3S)-1-[(2-methylpyrimidin-5-yl)methyl]piperidin-3-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H25F3N6
    2-[(3S)-1-[(2-methylpyrimidin-5-yl)methyl]piperidin-3-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-(4-methylpyrazol-1-yl)-1-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone —— C18H23F3N6O
    2-(4-methylpyrazol-1-yl)-1-[(2R)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]ethanone
    —— 3-(4-methylpyrazol-1-yl)-1-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one —— C19H25F3N6O
    3-(4-methylpyrazol-1-yl)-1-[(2S)-2-[(5R,7R)-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]propan-1-one
    —— 2-[(2R)-1-[(3-methylpyridin-4-yl)methyl]pyrrolidin-2-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H24F3N5
    2-[(2R)-1-[(3-methylpyridin-4-yl)methyl]pyrrolidin-2-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— (5S,7R)-2-[(2S)-1-[(3-methylpyridin-4-yl)methyl]piperidin-2-yl]-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C22H30F3N5
    (5S,7R)-2-[(2S)-1-[(3-methylpyridin-4-yl)methyl]piperidin-2-yl]-5-propan-2-yl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine
    —— 2-[(3S)-1-[(3-methylpyridin-4-yl)methyl]piperidin-3-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C22H26F3N5
    2-[(3S)-1-[(3-methylpyridin-4-yl)methyl]piperidin-3-yl]-5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 3-methyl-5-(3-methylpyridin-2-yl)-2-thiophen-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one —— C17H14N4OS
    3-methyl-5-(3-methylpyridin-2-yl)-2-thiophen-2-yl-1H-pyrazolo[1,5-a]pyrimidin-7-one
    —— 2-[(3S)-1-[(2-methoxy-3-methylphenyl)methyl]pyrrolidin-3-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine —— C21H23F3N4O
    2-[(3S)-1-[(2-methoxy-3-methylphenyl)methyl]pyrrolidin-3-yl]-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
    —— 2-(2,6-dimethylphenoxy)-1-[(2S)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)pyrrolidin-1-yl]ethanone —— C21H24N4O2
    2-(2,6-dimethylphenoxy)-1-[(2S)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)pyrrolidin-1-yl]ethanone
    —— 1-[(2S)-2-(2-tert-butylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-3-(5-methylpyrazol-1-yl)propan-1-one —— C22H30N6O
    1-[(2S)-2-(2-tert-butylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]-3-(5-methylpyrazol-1-yl)propan-1-one
    —— 2-methyl-5-[(3S)-1-[(6-methylpyridin-2-yl)methyl]piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine —— C19H24N6
    2-methyl-5-[(3S)-1-[(6-methylpyridin-2-yl)methyl]piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
    —— 1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2,6-dimethylphenoxy)ethanone —— C23H30F2N4O2
    1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2,6-dimethylphenoxy)ethanone
    —— 3-(5-methylfuran-2-yl)-1-[(3R)-3-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]propan-1-one —— C20H24N4O2
    3-(5-methylfuran-2-yl)-1-[(3R)-3-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]propan-1-one
    —— (6-methylpyridin-3-yl)-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone —— C21H22F3N5O
    (6-methylpyridin-3-yl)-[(2R)-2-[5-propan-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]pyrrolidin-1-yl]methanone
    —— [(3R)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(6-methylpyridin-3-yl)methanone —— C23H31F2N5O
    [(3R)-3-[(5S,7R)-2-tert-butyl-7-(difluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(6-methylpyridin-3-yl)methanone
    —— [(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(6-methylpyridin-3-yl)methanone —— C20H25F2N5O
    [(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-(6-methylpyridin-3-yl)methanone
    —— 3-(3,4-dimethylphenyl)sulfonyl-1-[(2S)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)pyrrolidin-1-yl]propan-1-one —— C22H26N4O3S
    3-(3,4-dimethylphenyl)sulfonyl-1-[(2S)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)pyrrolidin-1-yl]propan-1-one
    —— (2R)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(3,4-dimethylphenoxy)propan-1-one —— C24H32F2N4O2
    (2R)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(3,4-dimethylphenoxy)propan-1-one
    —— 1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methyl-2-(4-methylphenoxy)propan-1-one —— C24H32F2N4O2
    1-[(3S)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-methyl-2-(4-methylphenoxy)propan-1-one
    —— 4-methyl-N-[(1S)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-phenylethyl]-1,2,5-oxadiazole-3-carboxamide —— C19H18N6O3
    4-methyl-N-[(1S)-2-(2-methyl-7-oxo-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-phenylethyl]-1,2,5-oxadiazole-3-carboxamide
    —— 2-(2-methoxy-4-methylphenoxy)-1-[(2R)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]ethanone —— C22H26N4O3
    2-(2-methoxy-4-methylphenoxy)-1-[(2R)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]ethanone
    —— (2R)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2,4-dimethylphenoxy)propan-1-one —— C24H32F2N4O2
    (2R)-1-[(3R)-3-[(5S,7R)-7-(difluoromethyl)-2-methyl-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]piperidin-1-yl]-2-(2,4-dimethylphenoxy)propan-1-one
    —— 7-[(3R)-1-benzylpyrrolidin-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine —— C18H20N4
    7-[(3R)-1-benzylpyrrolidin-3-yl]-2-methylpyrazolo[1,5-a]pyrimidine
    —— 4-(2-fluorophenoxy)-1-[(2R)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]butan-1-one —— C22H25FN4O2
    4-(2-fluorophenoxy)-1-[(2R)-2-(2-methylpyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl]butan-1-one
    —— (5R,7R)-2-[(2S)-1-[(2-methoxy-5-methylphenyl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine —— C21H27F3N4O
    (5R,7R)-2-[(2S)-1-[(2-methoxy-5-methylphenyl)methyl]pyrrolidin-2-yl]-5-methyl-7-(trifluoromethyl)-1,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine