boeravinone C | 117176-19-9

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: boeravinone C
• 英文别名: (6aR,12aS)-4,11,12a-trihydroxy-9-methoxy-10-methyl-6,6a-dihydrochromeno[3,4-b]chromen-12-one
• CAS: 117176-19-9
• 化学式: C₁₈H₁₆O₇
• 分子量: 344.321
• InChiKey: ZVSXALWTWGTZSP-ACJLOTCBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  25
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  105
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  boeravinone C 在 sodium tetrahydroborate 作用下， 以 甲醇 为溶剂， 生成 (6aR,12R,12aR)-9-Methoxy-10-methyl-6,6a-dihydro-12H-chromeno[3,4-b]chromene-4,11,12,12a-tetraol
  参考文献：
  名称：

  Structure and NMR spectra of boeravinone C, a new rotenoid analogue from Boerhaavia diffusa LINN.

  摘要：

  A new rotenoid analogue, boeravinone C, has been isolated from the root of (Boerhaavia)___- (diffusa)___- Linn (Nyctaginaceae) and its structure has been determined by means of 2-D NMR. The 1H-NMR of boeravinone C showed unusual splitting patterns due to ABC spin systems. These splitting patterns were analyzed by simulation.

  DOI：

  10.1248/cpb.36.2289

文献信息

• KADOTA, SHIGETOSHI;LAMI, NZUNZU;TESUKA, YASUHIRO;KIKUCHI, TOHRU, CHEM. AND PHARM. BULL., 36,(1988) N 6, C. 2289-2292
  作者：KADOTA, SHIGETOSHI、LAMI, NZUNZU、TESUKA, YASUHIRO、KIKUCHI, TOHRU

  DOI：——

  日期：——
• PROCESS FOR ISOLATION OF EUPALITIN (3-O-BETA-D-GALACTOPYRANOSIDE) FROM BOERHAVIA DIFFUSA
  申请人：COUNCIL OF SCIENTIFIC ANDINDUSTRIAL RESEARCH

  公开号：EP1485394A1

  公开（公告）日：2004-12-15
• STANDARDIZED BIOACTIVE HERBAL EXTRACTS
  申请人：Ranbaxy Laboratories Limited

  公开号：EP2139504A1

  公开（公告）日：2010-01-06
• Process for isolation of eupalitin from boerhavia diffusa
  申请人：——

  公开号：US20030175373A1

  公开（公告）日：2003-09-18

  The present invention relates to a process of isolation of bioactive eupalitin (3-O-&bgr;-D-galactopyranoside) of formula 1 possessing anti-osteoporosis activity by extraction of powdered leaves of Boerhavia diffusa, with better yield 1
• STANDARIZED BIOACTIVE HERBAL EXTRACTS
  申请人：Katiyar Chandra Kant

  公开号：US20100120902A1

  公开（公告）日：2010-05-13

  The present invention relates to standardized extracts of Boerhaavia diffusa, wherein the extracts have anti inflammatory and analgesic activities. The present invention also includes bioassay guided fractionation of Boerhaavia diffusa leading to the identification of bioactive markers; processes for the isolation of the bioactive markers; processes for the preparation of the extracts enriched with bioactive markers from Boerhaavia diffusa; pharmaceutical compositions comprising bioactive markers, or standardized extracts of Boerhaavia diffusa and methods of standardization of the extracts.