3,3-dichloro-1,2-diphenylprop-2-en-1-one | 40920-42-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮
• 英文名称: 3,3-dichloro-1,2-diphenylprop-2-en-1-one
• CAS: 40920-42-1
• 化学式: C₁₅H₁₀Cl₂O
• 分子量: 277.15
• InChiKey: LLYIXLMPXXUOIW-UHFFFAOYSA-N

物化性质

• 沸点：
  352.2±42.0 °C(Predicted)
• 密度：
  1.284±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3,3-dichloro-1,2-diphenylprop-2-en-1-one 在 钾硼氢 作用下， 以 甲醇 、 水 为溶剂， 生成 3,3-Dichlor-1,2-diphenyl-2-propen-1-ol
  参考文献：
  名称：

  Raulet,C., Bulletin de la Societe Chimique de France, 1974, p. 531 - 537

  摘要：

  DOI：
• 作为产物：
  描述：

  苯甲酰腈 在 三苯基膦 作用下， 反应 5.5h， 生成 3,3-dichloro-1,2-diphenylprop-2-en-1-one
  参考文献：
  名称：

  Raulet,C., Bulletin de la Societe Chimique de France, 1974, p. 531 - 537

  摘要：

  DOI：

文献信息

• Ruthenium(II)-Catalyzed Protocol for Preparation of Diverse α,β- and β,β-Dihaloenones from Diazodicarbonyls
  作者：Krishna Bahadur Somai Magar、Yong Rok Lee

  DOI：10.1002/adsc.201400348

  日期：2014.11.3

  AbstractEfficient one‐step syntheses of α,β‐ and β,β‐dihaloenones were achieved by ruthenium(II)‐catalyzed reactions between cyclic or acyclic diazodicarbonyl compounds and oxalyl chloride or oxalyl bromide in moderate to good yields. This methodology offers several significant advantages, which include ease of handling, mild reaction conditions, one‐step reaction, and the use of an effective and non‐toxic catalyst. The synthesized compounds were further transformed into highly functionalized novel molecules bearing aromatic rings on the enone moiety using the Suzuki reaction.magnified image
• AuFeAg hybrid nanoparticles as an efficient recyclable catalyst for the synthesis of α,β- and β,β-dichloroenones
  作者：Kanchan Mishra、Nagaraj Basavegowda、Yong Rok Lee

  DOI：10.1016/j.apcata.2015.09.014

  日期：2015.10

  A facile and green pioneer approach for the synthesis of stable trimetallic AuFeAg hybrid nanoparticles is described. This synthetic method is green-chemistry compatible and totally free of additives. The particle shape and size, surface chemistry, crystallinity, elemental composition, thermal and magnetic properties were investigated. The catalytic performance of the synthesized nanoparticles is also described. The hybrid nanocatalyst exhibited strong catalytic activity for the synthesis of alpha,beta- and beta,beta-dichloroenones, which are important synthetic intermediates in the preparation of natural products. The reason behind the catalytic performance of nano sized hybrid particles was attributed to their high specific surface area. In addition, the nanocatalyst was easy to separate from the reaction mixture using an external magnet and could be reused for five consecutive reactions without any significant loss of activity. Using the present method, the trimetallic hybrid combination can be designed for similar types of catalytic reactions. (C) 2015 Elsevier B.V. All rights reserved.
• KR2017/29685
  申请人：——

  公开号：——

  公开（公告）日：——
• Gompper, Rudolf; Kottmair, Eduard, Zeitschrift fur Naturforschung, B: Chemical Sciences, 1990, vol. 45, # 6, p. 833 - 847
  作者：Gompper, Rudolf、Kottmair, Eduard

  DOI：——

  日期：——