月桂醇肉豆蔻酸酯 | 2040-64-4

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 月桂醇肉豆蔻酸酯
• 中文别名: 十四酸十二酯
• 英文名称: tetradecanoic acid, dodecyl ester
• 英文别名: Lauryl myristate；dodecyl tetradecanoate
• CAS: 2040-64-4
• 化学式: C₂₆H₅₂O₂
• 分子量: 396.698
• InChiKey: DFQOCHPHORLRID-UHFFFAOYSA-N

物化性质

• 沸点：
  438.7±13.0 °C(Predicted)
• 密度：
  0.860±0.06 g/cm3(Predicted)
• LogP：
  10.68-12.25 at 20℃
• 保留指数：
  2751.9;2753
• 稳定性/保质期：

  存在于烟气中。

计算性质

• 辛醇/水分配系数(LogP)：
  11.9
• 重原子数：
  28
• 可旋转键数：
  24
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2915900090
• WGK Germany：
  3

反应信息

• 作为产物：
  描述：

  十二烷醇 、 肉豆蔻酸 在 Ph3PSO3 作用下， 以 neat (no solvent) 为溶剂， 反应 2.0h， 以76%的产率得到月桂醇肉豆蔻酸酯
  参考文献：
  名称：

  Efficient greener methodology for the preparation of bio-based phase change materials from lipids

  摘要：

  In the present work, a new, highly efficient and simple strategy has been developed for the synthesis of long chain esters from fatty acids and fatty alcohols as phase change materials. Equivalent amounts of the selected starting compounds were taken to the esterification reaction at 110 degrees C in a solventless medium. In order to catalyze the esterification reaction, non-hygroscopic triphenylphosphine-sulfur trioxide adduct was used (0.83 mmol%) which is an easily accessible compound. The relevant reaction was completed in a very short time (2 h) and under optimized esterification conditions, excellent conversion were reached. The targeted mono ester compounds (15 examples) were obtained in good to excellent yields even after a simple crystallization step (72-99%). Additionally, a catalyst reuse investigation and study covering the scale-up production of stearyl stearate was also carried out. The triphenylphosphine-sulfur trioxide catalyzed solvent free process can compete with existing processes and proved to be a cheaper, practical and environmentally-friendly method for the esterification of fatty acids and alcohols.

  DOI：

  10.1080/10426507.2020.1845681

文献信息

• [EN] NOVEL ANTIMICROBIAL PEPTIDES AND THEIR APPLICATION<br/>[FR] NOUVEAUX PEPTIDES ANTIMICROBIENS ET LEUR APPLICATION
  申请人：INFINITEC ACTIVOS S L

  公开号：WO2015135896A1

  公开（公告）日：2015-09-17

  The present invention relates to a compound of formula (I) and to compositions comprising said compound, as well as the use of said compound and/or said compositions to prevent fungal and/or bacterial growth.

  本发明涉及式(I)的化合物，以及包含该化合物的组合物，以及使用该化合物和/或所述组合物来防止真菌和/或细菌生长。
• [EN] COMPOUNDS REDUCING MALODOUR PERCEPTION AND THE USE THEREOF<br/>[FR] COMPOSÉS RÉDUISANT LA PERCEPTION DES MAUVAISES ODEURS ET LEUR UTILISATION
  申请人：CHEMCOM SA

  公开号：WO2018138369A1

  公开（公告）日：2018-08-02

  The present invention relates to new malodour-counteracting agents of formula (I) or stereoisomers thereof, particularly useful in blocking the olfactory perception of androstenone, Formula (I), wherein R1, R2, R3,R4, R5, R6, R7 and X have the same meaning as that defined in the claims. The present invention also relates to consumer products comprising said agents. The present invention also relates to the use of said agents to suppress or attenuate undesirable odour, as well as to methods to suppress or attenuate undesirable odour employing said compounds.

  本发明涉及公式(I)或其立体异构体的新型恶臭对抗剂，特别适用于阻断雄烯酮的嗅觉感知，公式(I)中，R1、R2、R3、R4、R5、R6、R7和X的含义与索赔中定义的相同。本发明还涉及包含所述对抗剂的消费产品。本发明还涉及使用所述对抗剂来抑制或减弱不良气味，以及使用这些化合物来抑制或减弱不良气味的方法。
• [EN] BISUREA GELLING AGENTS AND COMPOSITIONS<br/>[FR] AGENTS GÉLIFIANTS DE TYPE BIURÉE ET COMPOSITIONS ASSOCIÉES
  申请人：MILLIKEN & CO

  公开号：WO2013033300A1

  公开（公告）日：2013-03-07

  Bisurea gelling agents that impart a number of unexpected benefits within various gelled formulations and exhibit great versatility in terms of gelling capabilities for many types of solvents are provided. Such gelling agents should include pendant groups, such as sterically hindering alkyl groups attached to polyoxyalkylenated moieties that allow the gelling agent to be compatible with the target liquid system at elevated temperatures, while controlling and/or limiting the network formation and strength during the cooling cycle. The result is that a reliable, hard gel is formed that does not crash out of solution easily and that does not exhibit unwanted cracking or precipitating out within the final formulation. Alternatively, novel gelling agents having two urea groups but that are asymmetrical in configuration have been produced in order to provide the same control in temperature, compatibility, and efficiency. Final gelled formulations, such as antiperspirant sticks and other like consumer items, are provided as well within this invention.

  本文提供了一种Bisurea凝胶剂，它在各种凝胶配方中带来了许多意想不到的好处，并且在凝胶能力方面表现出极大的多样性，适用于许多类型的溶剂。这种凝胶剂应包括挂链基团，例如附加到聚氧烷基化物上的空间阻碍烷基基团，使凝胶剂在升高的温度下与目标液体系统兼容，同时在冷却周期中控制和/或限制网络形成和强度。结果是形成了可靠的坚硬凝胶，不易从溶液中崩解，不会在最终配方中出现不必要的开裂或沉淀。另外，为了提供相同的温度、兼容性和效率控制，还制备了具有两个脲基但配置不对称的新型凝胶剂。本发明还提供了最终的凝胶配方，例如止汗膏和其他类似的消费品。
• Pigment dispersions and cosmetic products containing the same
  申请人：——

  公开号：US20030235544A1

  公开（公告）日：2003-12-25

  There is provided a pigment surface treated with N-acylglycine hydroxyaluminum and/or N-acyl-N-methylglycine hydroxyaluminum, and a pigment dispersion which contains such surface treated pigment and a cosmetically acceptable oily material, and has an excellent dispersion stability and versatility (ease of dispersion and wide rage of usage). There can be also provided a cosmetic product which is stable as an emulsion and has a better usage than the existing products by using said surface treated pigment or said pigment dispersion. In the pigment dispersion for the cosmetic product, the pigment particles are easily and uniformly dispersed in short period of time at a high concentration in a cosmetically acceptable oily material.

  提供了一种使用N-酰基甘氨酸羟基铝和/或N-酰基-N-甲基甘氨酸羟基铝处理的颜料表面，以及一种包含这种表面处理颜料和化妆品可接受的油质材料的颜料分散体，具有优异的分散稳定性和多功能性（易于分散和广泛使用）。还可以提供一种化妆品产品，通过使用所述表面处理颜料或颜料分散体，该化妆品产品稳定为乳液，并且使用效果比现有产品更好。在化妆品产品的颜料分散体中，颜料粒子可以在短时间内以高浓度轻松均匀地分散在化妆品可接受的油质材料中。
• [EN] PHOTOCHEMICALLY STABLE, NON-LEACHING, BRIDGED POLYSILSESQUIOXANE BASED SUNSCREENS<br/>[FR] ÉCRANS SOLAIRES À BASE DE POLYSILSESQUIOXANES PONTÉS, SANS DÉCOLORATION ET PHOTOCHIMIQUEMENT STABLES
  申请人：UNIV ARIZONA

  公开号：WO2017132655A1

  公开（公告）日：2017-08-03

  Bridged polysilsesquioxane based sunscreens prepared as nanoparticles via oil/water microemulsion polymerization, sol-gel polymerizations, or a modified Stober process. Minimized leaching and decreased levels of photo-degradation were achieved with covalent incorporation, with bridged incorporation necessary to ensure isolation of the sunscreen and any photo-products from skin. SPF values of were found to be comparable to existing commercial sunscreens. Furthermore the bridged polysilsesquioxane based sunscreens can be classified as broad-spectrum, and rate from moderate to superior in terms of UVA protective ability.

  基于桥联聚硅氧烷的防晒霜可通过油/水微乳聚合、溶胶-凝胶聚合或改良的Stober工艺制备成纳米颗粒。通过共价结合，实现了最小化渗漏和降低光降解水平，桥联结合对确保防晒霜及任何光降解产物与皮肤隔离是必要的。SPF值发现与现有商业防晒霜相当。此外，基于桥联聚硅氧烷的防晒霜可被归类为广谱，其UVA保护能力在中等到优越之间。

表征谱图