N-辛基丙烯酰胺 | 10124-68-2

• 物质功能分类: 有机原料 - 氨基化合物 - 酰胺类化合物
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: N-辛基丙烯酰胺
• 英文名称: acrylic acid octylamide
• 英文别名: N-n-octyl acrylic amide；N-(n-octyl)acrylamide；N-octylprop-2-enamide；N-octylacrylamide；N-n-octylacrylamide；octyl acrylamide
• CAS: 10124-68-2
• 化学式: C₁₁H₂₁NO
• mdl: MFCD24231063
• 分子量: 183.294
• InChiKey: AWGZKFQMWZYCHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.727
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 海关编码：
  2924199090

反应信息

• 作为反应物：
  描述：

  N-辛基丙烯酰胺 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 作用下， 以 二氯甲烷 为溶剂， 以93%的产率得到Fumarsaeure-bis-octylamid
  参考文献：
  名称：

  Efficient synthesis of fumaric amides through cross-metathesis of acrylic amides with the NHC Grubbs ruthenium catalyst

  摘要：

  Application of the second generation Grubbs metathesis catalyst for the homo-cross-metathesis of acroyl amides from chiral amines is reported. This efficient and high-yielding reaction provides a side-product free synthesis of fumaric acid diamides which are formed with complete (E)-selectivity under the reaction conditions. In particular, products which cannot be synthesized from the corresponding fumaroyl chloride via classic condensation route can now be provided in excellent yields (88-98%) with a catalyst loading from 2.5 mol% to even 0.375 mol%. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2005.07.116
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 aluminum oxide 作用下， 生成 N-辛基丙烯酰胺
  参考文献：
  名称：

  Method of producing n-alkyl acrylamides

  摘要：

  公开号：

  US02534585A1

文献信息

• Copolymers Based on N-Vinylpyrrolidone and Branched Aliphatic Carbonxylic Acids, and Their Use as Solubilizers
  申请人：Angel Maximilian

  公开号：US20080200564A1

  公开（公告）日：2008-08-21

  Copolymers comprising: (a) 60 to 99% by weight of at least one monomer selected from the group consisting of N-vinyllactams, N-vinylamides, and mixtures thereof; (1) 1 to 40% by weight of at least one monomer selected from the group consisting of vinyl esters of aliphatic branched C 8 -C 30 -carboxylic acids; (c) 0 to 30% by weight of vinyl acetate; and (d) 0 to 39% by weight of at least one additional free-radically copolymnerizable monomer; wherein the % by weight content of components (a), (b), (c) and (d) totals 100%, and with the proviso that the total amount of component (b) and component (c) combined is 1 to 40% by weight based on the copolymer, are described along with methods of using such copolymers to solubilize substances which are insoluble in water, substances which are only sparingly soluble in water, and combinations thereof.

  共聚物包含：（a）60至99重量百分比的至少一种单体，选自N-乙烯基内酰胺、N-乙烯酰胺和它们的混合物；（b）1至40重量百分比的至少一种单体，选自支链的C8-C30脂肪族羧酸的乙烯酯；（c）0至30重量百分比的乙酸乙烯酯；和（d）0至39重量百分比的至少一种额外的自由基共聚单体；其中，组分（a）、（b）、（c）和（d）的重量百分比总和为100%，并且有条件规定组分（b）和组分（c）的总和基于共聚物为1至40重量百分比。还描述了使用这样的共聚物来增溶水不溶性物质、水微溶性物质以及它们的组合的方法。
• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• Photochemistry of Epoxynaphthoquinones. 8. Endo-Stereoselective Photocycloaddition of 2,3-Epoxy-2,3-dihydro-2,3-dimethyl-1,4-naphthoquinone to Olefins Containing Amide Group
  作者：Kazuhiro Maruyama、Atsuhiro Osuka、Katsuhiko Nakagawa

  DOI：10.1246/bcsj.60.1021

  日期：1987.3

  Irradiation of a benzene solution of 2,3-epoxy-2,3-dihydro-2,3-dimethyl-1,4-naphthoquinone with olefins containing amide group, i.e., N-substituted acrylamides and N-allylcarboxamides predominantly gave the endo-cycloadducts. Upon further irradiation, the cycloadducts underwent photorearrangement to give spirophthalides and alkylidenephthalides.

  苯溶液中2,3-环氧-2,3-二氢-2,3-二甲基-1,4-萘醌与含有酰胺基的烯烃，即N-取代丙烯酰胺和N-烯丙基羧酰胺的照射主要生成endo-环加成物。进一步照射后，这些环加成物发生光重排，生成螺苯并二氢吡喃酮和烷叉基苯并二氢吡喃酮。
• Innervated artificial tissues and uses thereof
  申请人：Griffith May

  公开号：US20060034807A1

  公开（公告）日：2006-02-16

  A three dimensional, innervated artificial tissue comprising a bio-synthetic matrix is provided. The artificial tissue supports cell growth, including surface coverage and three-dimensional cell in-growth, as well as nerve in-growth. Methods of preparing the innervated artificial tissue and methods of innervating artificial tissues or tissue substitutes are also provided. The artificial tissue is useful for in vitro testing of various pharmaceutical, cosmetic and household products.

  提供了一种包括生物合成基质的三维神经化人工组织。这种人工组织支持细胞生长，包括表面覆盖和三维细胞生长，以及神经生长。还提供了制备这种神经化人工组织的方法，以及神经化人工组织或组织替代品的方法。这种人工组织对于体外测试各种药物、化妆品和家用产品非常有用。
• ACRYLIC PRESSURE-SENSITIVE ADHESIVES WITH AZIRIDINE CROSSLINKING AGENTS
  申请人：KAVANAGH Maureen A.

  公开号：US20090208740A1

  公开（公告）日：2009-08-20

  A pre-adhesive composition is described comprising an acid-functional (meth)acrylate copolymer and an aziridine crosslinking agent, which when crosslinked provides a pressure-sensitive adhesive and pressure-sensitive adhesive articles.

  描述了一种预粘合组合物，包括一个含酸官能基的（甲基）丙烯酸酯共聚物和一个环氧乙烷交联剂，交联后提供一种压敏粘合剂和压敏粘合剂制品。