Fumarsaeure-bis-octylamid | 113060-38-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Fumarsaeure-bis-octylamid
• 英文别名: (E)-N,N'-dioctylbut-2-enediamide
• CAS: 113060-38-1
• 化学式: C₂₀H₃₈N₂O₂
• 分子量: 338.534
• InChiKey: WOLOATKQQOJIGE-FOCLMDBBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  24
• 可旋转键数：
  16
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N-Octyl maleamic acid 在 sodium acetate 作用下， 以 乙酸酐 为溶剂， 生成 Fumarsaeure-bis-octylamid
  参考文献：
  名称：

  Maleamic and Citraconamic Acids, Methyl Esters, and Imides

  摘要：

  DOI：

  10.1021/jo01076a038

文献信息

• Efficient synthesis of fumaric amides through cross-metathesis of acrylic amides with the NHC Grubbs ruthenium catalyst
  作者：Jan Streuff、Kilian Muñiz

  DOI：10.1016/j.jorganchem.2005.07.116

  日期：2005.12

  Application of the second generation Grubbs metathesis catalyst for the homo-cross-metathesis of acroyl amides from chiral amines is reported. This efficient and high-yielding reaction provides a side-product free synthesis of fumaric acid diamides which are formed with complete (E)-selectivity under the reaction conditions. In particular, products which cannot be synthesized from the corresponding fumaroyl chloride via classic condensation route can now be provided in excellent yields (88-98%) with a catalyst loading from 2.5 mol% to even 0.375 mol%. (c) 2005 Elsevier B.V. All rights reserved.
• Maleamic and Citraconamic Acids, Methyl Esters, and Imides
  作者：NARIMAN B. MEHTA、ARTHUR P. PHILLIPS、(MRS.) FLORENCE FU LUI、RONALD E. BROOKS

  DOI：10.1021/jo01076a038

  日期：1960.6