1-deoxy-D-sedoheptulose 7-phosphate | 87403-37-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-deoxy-D-sedoheptulose 7-phosphate
• 英文别名: 1-Deoxy-D-altro-heptulose phosphate；1-Deoxy-D-altro-heptulose 7-phosphate；[(2R,3R,4R,5S)-2,3,4,5-tetrahydroxy-6-oxoheptyl] dihydrogen phosphate
• CAS: 87403-37-0
• 化学式: C₇H₁₅O₉P
• 分子量: 274.164
• InChiKey: QIIZYFWCULOBMW-GBNDHIKLSA-N

物化性质

• 沸点：
  669.1±65.0 °C(Predicted)
• 密度：
  1.732±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -4.3
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  165
• 氢给体数：
  6
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 1-deoxy-D-sedoheptulose 7-phosphate 在 4-二甲氨基吡啶 作用下， 以 吡啶 为溶剂， 生成 3,4,5,6,7-penta-O-acetyl-1-deoxy-keto-D-altro-heptulose
  参考文献：
  名称：

  Enzymatic synthesis of 1-deoxysugar-phosphates using E. coli 1-deoxy-d-xylulose 5-phosphate synthase

  摘要：

  The thiamine diphosphate-dependent enzyme 1-deoxy-D-xylulose 5-phosphate synthase from E. coli can use D-erythrose 4-phosphate and D-ribose 5-phosphate as alternative substrates. These reactions were used for the production of 1-deoxy-D-fructose 6-phosphate and 1-deoxy-D-sedoheptulose 7-phosphate and have potential application for the biosynthesis of other 1-deoxysugar phosphates. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)02018-x
• 作为产物：
  描述：

  (2,3,4-三羟基-5-氧代戊基)磷酸二氢酯 、 sodium pyruvate 在 焦磷酸硫胺素 、 2-巯基乙醇 1-deoxy-D-xylulose 5-phosphate synthase from E_. coli 、 三羟甲基氨基甲烷盐酸盐 、 magnesium chloride 作用下， 以 水 为溶剂， 反应 4.0h， 生成 1-deoxy-D-sedoheptulose 7-phosphate
  参考文献：
  名称：

  Enzymatic synthesis of 1-deoxysugar-phosphates using E. coli 1-deoxy-d-xylulose 5-phosphate synthase

  摘要：

  The thiamine diphosphate-dependent enzyme 1-deoxy-D-xylulose 5-phosphate synthase from E. coli can use D-erythrose 4-phosphate and D-ribose 5-phosphate as alternative substrates. These reactions were used for the production of 1-deoxy-D-fructose 6-phosphate and 1-deoxy-D-sedoheptulose 7-phosphate and have potential application for the biosynthesis of other 1-deoxysugar phosphates. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(02)02018-x

文献信息

• Yokota, Akira; Sasajima, Ken-ichi, Agricultural and Biological Chemistry, 1983, vol. 47, # 7, p. 1545 - 1553
  作者：Yokota, Akira、Sasajima, Ken-ichi

  DOI：——

  日期：——
• Enzymatic synthesis of 1-deoxysugar-phosphates using E. coli 1-deoxy-d-xylulose 5-phosphate synthase
  作者：Jordi Querol、Catherine Grosdemange-Billiard、Michel Rohmer、Albert Boronat、Santiago Imperial

  DOI：10.1016/s0040-4039(02)02018-x

  日期：2002.11

  The thiamine diphosphate-dependent enzyme 1-deoxy-D-xylulose 5-phosphate synthase from E. coli can use D-erythrose 4-phosphate and D-ribose 5-phosphate as alternative substrates. These reactions were used for the production of 1-deoxy-D-fructose 6-phosphate and 1-deoxy-D-sedoheptulose 7-phosphate and have potential application for the biosynthesis of other 1-deoxysugar phosphates. (C) 2002 Elsevier Science Ltd. All rights reserved.