1-丁氧基-1-甲氧基甲烷 | 76050-97-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1-丁氧基-1-甲氧基甲烷
• 英文名称: butoxy(methoxy)methane
• 英文别名: 1-(Methoxymethoxy)butane
• CAS: 76050-97-0
• 化学式: C₆H₁₄O₂
• 分子量: 118.176
• InChiKey: INMMGKHASIHGGZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  8
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-丁氧基-1-甲氧基甲烷 、 二叔丁基过氧化物 生成 甲丁醚 、 甲酸甲酯 、 甲酸丁酯 、 正丁醛 、 叔丁醇
  参考文献：
  名称：

  Kalashnikov, S. M.; Zlotskii, S. S.; Imashev, U. B., Journal of Organic Chemistry USSR (English Translation), 1980, p. 1379 - 1382

  摘要：

  DOI：
• 作为产物：
  描述：

  sodium methylate 、 氯甲基丁基醚 在 乙醚 作用下， 生成 1-丁氧基-1-甲氧基甲烷
  参考文献：
  名称：

  Leimu, Annales Academiae Scientiarum Fennicae, Series A2: Chemica, 1946, # 19, p. 8 - 11

  摘要：

  DOI：

文献信息

• A Facile Preparation of Methoxymethyl Ethers of Primary and Secondary Alcohols with Dimethoxymethane Catalysed by Expansive Graphite
  作者：Tong-Shou Jin、Tong-Shuang Li、Yong-Tao Gao

  DOI：10.1080/00032719808006481

  日期：1998.3.1

  Abstract An easy preparation of methoxymethyl ethers of primary and secondary alcohols with dimethoxymethane has been carried out in excellent yield under catalysis of expansive graphite.

  摘要 在膨胀石墨的催化下，以二甲氧基甲烷简单地制备了伯醇和仲醇的甲氧基甲基醚，收率良好。
• Methods for Producing Fluorine-Containing Hydroxyaldehyde, Fluorine-Containing Propanediol, and Fluorine-Containing Alcohol Monomer
  申请人：Central Glass Company, Limited

  公开号：US20150361026A1

  公开（公告）日：2015-12-17

  As shown by the following reaction formula, disclosed is a fluorine-containing hydroxyaldehyde production method, including the step of obtaining a fluorine-containing hydroxyaldehyde represented by the general formula (1) by reacting a fluorine-containing ketone represented by the general formula (4) and an aldehyde represented by the general formula (5) in the presence of an organic base selected from a heterocyclic compound which contains a nitrogen atom in its ring or a tertiary amine. By this production method, it is possible to obtain the fluorine-containing hydroxyaldehyde in a high yield. Furthermore, it is possible to easily obtain in high yields a fluorine-containing propanediol, which is a derivative of this fluorine-containing hydroxyaldehyde, and a fluorine-containing alcohol monomer by using the same.

  根据以下反应方程式，揭示了一种含氟羟基醛的生产方法，包括通过在选择的含氟酮（通式（4）表示）和醛（通式（5）表示）在含有从含有氮原子的杂环化合物或三级胺中选择的有机碱的情况下反应，获得由通式（1）表示的含氟羟基醛的步骤。通过这种生产方法，可以高产率地获得含氟羟基醛。此外，可以通过使用相同方法轻松高产率地获得含氟丙二醇（这是这种含氟羟基醛的衍生物）和含氟醇单体。
• Melamine Trisulfonic Acid (MTSA): A New Efficient Catalyst for the Chemoselective Methoxymethylation of Alcohols
  作者：Farhad Shirini、Mohammad Ali Zolfigol、Jalal Albadi

  DOI：10.1080/00397910903026707

  日期：2010.2.26

  Melamine trisulfonic acid, which is easily prepared by the reaction of melamine with neat chlorosulfonic acid, is able to efficiently catalyze the chemoselective methoxymethylation of alcohols with dimethoxymethane (DMM). All reactions were performed under mild and completely heterogeneous reaction conditions in good to high yields.

  三聚氰胺三磺酸很容易通过三聚氰胺与纯氯磺酸反应制备，能够有效地催化醇与二甲氧基甲烷（DMM）的化学选择性甲氧基甲基化。所有反应均在温和且完全非均相的反应条件下以良好至高产率进行。
• HALOALKYLSULFONANILIDE DERIVATIVE
  申请人：Kai Masanori

  公开号：US20120029187A1

  公开（公告）日：2012-02-02

  Novel herbicides are provided. A haloalkylsulfonanilide derivative represented by the formula (1) or an agrochemically acceptable salt thereof: the formula (1): wherein Z is —C(R 9 )(R 10 )— or —N(R 11 )—, A is an oxygen atom, a sulfur atom or —N(R 12 )—, W is an oxygen atom or a sulfur atom, m is an integer of from 0 to 3, n is an integer of from 0 to 3, m+n is from 1 to 3, R 1 is halo C 1 -C 6 alkyl, R 2 is a hydrogen atom, C 1 -C 6 alkyl or the like, each of R 3 and R 4 is independently a hydrogen atom, C 1 -C 6 alkyl or the like, each of R 5 , R 6 , R 7 , R 8 , R 9 and R 10 is independently a hydrogen atom, a halogen, C 1 -C 6 alkyl or the like, each of R 11 and R 12 is a hydrogen atom, C 1 -C 6 alkyl, halo C 1 -C 6 alkyl or the like, and X is independently a hydrogen atom, a halogen, C 1 -C 6 alkyl, or the like.

  提供新型除草剂。 一种由式（1）表示的卤烷基磺酰苯胺衍生物或其农药可接受的盐： 式（1）： 其中Z为—C(R9)(R10)—或—N(R11)—，A为氧原子、硫原子或—N(R12)—，W为氧原子或硫原子，m为0至3的整数，n为0至3的整数，m+n为1至3，R1为卤代C1-C6烷基，R2为氢原子、C1-C6烷基或类似物，R3和R4中的每一个独立地为氢原子、C1-C6烷基或类似物，R5、R6、R7、R8、R9和R10中的每一个独立地为氢原子、卤素、C1-C6烷基或类似物，R11和R12中的每一个为氢原子、C1-C6烷基、卤代C1-C6烷基或类似物，X独立地为氢原子、卤素、C1-C6烷基或类似物。
• Catalytic application of sulfamic acid-functionalized magnetic Fe₃O₄ nanoparticles (SA-MNPs) for protection of aromatic carbonyl compounds and alcohols: experimental and theoretical studies
  作者：Sepideh Khaef、Mohammad Ali Zolfigol、Avat Arman Taherpour、Meysam Yarie

  DOI：10.1039/d0ra09087e

  日期：——

  Protection techniques of functional groups within the structure of organic compounds are important synthetic methods against unwanted attacks from various reagents during synthetic sequences. Acetal and thioacetal groups are well known as protective functional groups in organic reactions. In this study, acetalization of carbonyl compounds with diols and dithiols and methoxymethylation of alcohols with

  有机化合物结构内官能团的保护技术是重要的合成方法，可防止合成过程中各种试剂的不必要的攻击。众所周知，缩醛和硫缩醛基团是有机反应中的保护性官能团。在这项研究中，使用氨基磺酸功能化磁性Fe 3 O 4纳米粒子（SA-MNPs）作为非均相固体酸催化剂，进行了羰基化合物与二醇和二硫醇的缩醛化以及醇与甲醛二甲基缩醛（FDMA）的甲氧基甲基化。产品通过 FT-IR 和 NMR 光谱进行表征。一些产品的结构和电子特性是通过量子力学（QM）方法计算的。根据计算结果获得的立体化学和电子性质，我们认为超共轭在2-苯基-1,3-二氧戊环衍生物的结构性质以及2-苯基-1,3-二氧戊环衍生物的π电子之间的电子转移中起着关键作用。具有S原子3d轨道的芳香环影响2-苯基-1,3-二噻烷衍生物的结构。