溴酚蓝钠盐 | 62625-28-9

• 物质功能分类: 生物化工 - 生化试剂 - 生物染料
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 溴酚蓝钠盐
• 中文别名: 溴酚蓝,钠盐
• 英文名称: bromophenol blue
• 英文别名: bromophenol blue sodium salt；Sodium;2,6-dibromo-4-[(3,5-dibromo-4-oxocyclohexa-2,5-dien-1-ylidene)-(2-sulfophenyl)methyl]phenolate；sodium;2,6-dibromo-4-[(3,5-dibromo-4-oxocyclohexa-2,5-dien-1-ylidene)-(2-sulfophenyl)methyl]phenolate
• CAS: 62625-28-9
• 化学式: C₁₉H₉Br₄O₅S*Na
• 分子量: 691.949
• InChiKey: TWKDJMRHSLWRFI-UHFFFAOYSA-M

物化性质

• 熔点：
  >300°C
• 密度：
  0.954 g/mL at 20 °C
• 溶解度：
  溶于水、乙醇
• 最大波长(λmax)：
  589nm, 383nm
• 稳定性/保质期：
  在常温常压下稳定，应远离氧化剂。

计算性质

• 辛醇/水分配系数(LogP)：
  2.77
• 重原子数：
  30
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  103
• 氢给体数：
  1
• 氢受体数：
  5

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S37/39
• 危险类别码：
  R36/37/38
• WGK Germany：
  3
• 海关编码：
  29349990
• RTECS号：
  SJ7453000
• 危险品运输编号：
  UN 2265 3
• 储存条件：
  存放在密封容器内，并置于阴凉、干燥处。

SDS

Name:	Bromophenol Blue Sodium Salt Reagent ACS Material Safety Data Sheet
Synonym:	4,4'-(3h-1,2 benzoxathiol-3-ylidene)bis(2,6-dibromophenol s,s-dioxide monosodium sal
CAS:	62625-28-9

Section 1 - Chemical Product MSDS Name:Bromophenol Blue Sodium Salt Reagent ACS Material Safety Data Sheet
Synonym:4,4'-(3h-1,2 benzoxathiol-3-ylidene)bis(2,6-dibromophenol s,s-dioxide monosodium sal

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Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
62625-28-9	Bromophenol blue, sodium salt	100	263-653-2

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

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Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation. This product contains an anionic dye.
Similar dyes have not caused injury to the cornea or conjunctiva in documented exposure cases with human or rabbit eyes.
Skin:
May cause skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

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Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician:

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Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

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Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

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Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

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Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 62625-28-9: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

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Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: Not available.
Odor: none reported
pH: Not available.
Vapor Pressure: Not applicable.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C19H9Br4NaO5S
Molecular Weight: 691.95

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Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide, hydrogen bromide.
Hazardous Polymerization: Has not been reported.

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Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 62625-28-9 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Bromophenol blue, sodium salt - Not listed by ACGIH, IARC, or NTP.

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Section 12 - ECOLOGICAL INFORMATION

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Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

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Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

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Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
WGK (Water Danger/Protection)
CAS# 62625-28-9: No information available.
Canada
CAS# 62625-28-9 is listed on Canada's DSL List.
CAS# 62625-28-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 62625-28-9 is listed on the TSCA inventory.

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SECTION 16 - ADDITIONAL INFORMATION
N/A

制备方法与用途

用途

该物质用作酸碱指示剂，在pH值为3.0（黄色）～4.6（蓝色）的范围内变色。

反应信息

• 作为反应物：
  描述：

  溴酚蓝钠盐 在 α-Fe₂O₃ nanoparticles 作用下， 反应 4.0h， 生成 二氧化碳
  参考文献：
  名称：

  使用石榴籽提取物的生物分子可持续制备赤铁矿 (α-Fe 2 O 3 ) 纳米颗粒，用于非常规太阳能光驱动的有机染料光催化修复

  摘要：

  寻求一种有效的策略来开发用于染料降解的廉价且高度稳定的光催化剂材料，对于解决因染料滥用引起的全球环境问题具有重要意义。在此，我们报道了使用石榴籽提取物生物分子以环保方式合成极其高效且高度可持续的赤铁矿纳米颗粒（α-Fe 2 O 3 NPs）。合成的α-Fe 2 O 3 NPs的形貌和相纯度是通过一系列表征技术进行的。FESEM 和 TEM 分析表明合成的 α-Fe 2 O 3纳米颗粒为不规则形状，平均尺寸为 26.53 nm，而纳米颗粒的 BET 表面积估计为 31.52 m 2 /g，平均孔径为 5.54 nm。α-Fe 2 O 3 NPs 在室温下表现出典型的铁磁行为。α-Fe 2 O 3 NPs 中元素的氧化态通过 X 射线光电子能谱 (XPS) 分析得到证实，而 α-Fe 2 O 3 NPs上的电荷为 -10.6 mV。制备的α-Fe 2 O 3NPs 用于阴离子刚果红 (CR) 和溴酚蓝

  DOI：

  10.1016/j.molliq.2021.116729
• 作为产物：
  描述：

  phenolsulphophthaleine sodium salt 在 Agrocybe aegerita heme-thiolate peroxygenase 、 双氧水 、 sodium bromide 作用下， 生成 溴酚蓝钠盐
  参考文献：
  名称：

  血红素-硫醇酶对氧-原子转移的驱动力

  摘要：

  绝对：已经测量了Aae APO 催化反应中三个氧化还原对的氧化还原电位，从而首次将这些血红素硫醇反应中间体置于绝对能量标度上。根据这些氧化还原电位讨论了轴向硫醇盐配体的重要性和化合物 II Ferrel 氧原子的基本性质。

  DOI：

  10.1002/anie.201302137

文献信息

• [EN] DIFFERENTIATION MODULATING AGENTS AND USES THEREFOR<br/>[FR] AGENTS DE MODULATION DE LA DIFFERENCIATION ET UTILISATIONS ASSOCIEES
  申请人：UNIV QUEENSLAND

  公开号：WO2005065686A1

  公开（公告）日：2005-07-21

  This invention discloses methods and agents for modulating the differentiation potential and/or proliferation of preadipocytes. More particularly, the present invention discloses methods and agents for modulating a fibroblast growth factor (FGF) signalling pathway, especially the FGF-1 or FGF-2 signalling pathway, for treating or preventing adiposity-related conditions including, but not limited to, obesity, lipoma and lipomatosis.

  该发明揭示了调节前脂肪细胞分化潜能和/或增殖的方法和药剂。更具体地，本发明揭示了调节成纤维细胞生长因子（FGF）信号通路的方法和药剂，特别是FGF-1或FGF-2信号通路，用于治疗或预防与脂肪相关的疾病，包括但不限于肥胖、脂肪瘤和脂肪增生。
• Methods for coating surfaces with antimicrobial agents
  申请人：The Board of Regents of the University of Texas System

  公开号：US10589003B2

  公开（公告）日：2020-03-17

  Disclosed are methods for coating or impregnating a surface with an antimicrobial agent that involve contacting the surface with a composition that includes an antimicrobial agent and a solvent, and curing the surface by applying heat. Also disclosed are methods for reducing the risk of development or progression of an infection in a subject in need of a medical device, that involve coating or impregnating a surface of the medical device with an antimicrobial agent and then curing the surface by applying heat, wherein the risk of development or progression of an infection is reduced.

  本发明公开了用抗菌剂涂覆或浸渍表面的方法，包括用包括抗菌剂和溶剂的组合物接触表面，并通过加热固化表面。还公开了降低需要使用医疗器械的受试者发生或恶化感染风险的方法，包括用抗菌剂涂覆或浸渍医疗器械表面，然后通过加热固化表面，从而降低发生或恶化感染的风险。
• Optoelectronic and microfluidic integration for miniaturized spectroscopic devices
  申请人：California Institute of Technology

  公开号：US20030235924A1

  公开（公告）日：2003-12-25

  Techniques for integrating optoelectronic system and microfluidic system. An apparatus for optical analysis includes a detector system and a microfluidic system on the detector system. The apparatus is free from any lens system between the microfluidic system and the detector system. Methods of making such an apparatus and using such an apparatus are also disclosed.

  集成光电系统和微流体系统的技术。用于光学分析的设备包括一个检测器系统和检测器系统上的微流体系统。该装置在微流体系统和检测器系统之间没有任何透镜系统。还公开了制造这种装置和使用这种装置的方法。
• Composite compositions for electrophoresis
  申请人：Updyke Timothy

  公开号：US20050121325A1

  公开（公告）日：2005-06-09

  The invention is drawn to composite agarose/acrylamide compositions and gels. In particular it relates to gels for the separation of molecules, particularly macromolecules such as proteins. The invention is also directed to the preparation of composite gels, the separation of molecules by techniques such as electrophoresis using such gels, and the transfer of proteins from such gels to a transfer membrane using an immunoblot transfer gel.

  本发明涉及复合琼脂糖/丙烯酰胺组合物和凝胶。本发明尤其涉及用于分离分子，特别是蛋白质等大分子的凝胶。本发明还涉及复合凝胶的制备，使用这种凝胶通过电泳等技术分离分子，以及使用免疫印迹转移凝胶将蛋白质从这种凝胶转移到转移膜上。
• Mohamed; Dossouki; Moustafa, Egyptian Journal of Chemistry, 2008, vol. 51, # 1, p. 113 - 123
  作者：Mohamed、Dossouki、Moustafa、Ghoname

  DOI：——

  日期：——