3β-hydroxy olean-11-en-28->13 oate | 84164-78-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: 3β-hydroxy olean-11-en-28->13 oate
• 英文别名: 3β-hydroxyolean-11-en-13β,28-olide；oleanolic acid lactone；(1S,4S,5R,8R,10S,13S,14R,17S,18R)-10-hydroxy-4,5,9,9,13,20,20-heptamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracos-15-en-23-one
• CAS: 84164-78-3
• 化学式: C₃₀H₄₆O₃
• 分子量: 454.693
• InChiKey: VQUPEZXRIUOIJE-LZRJWOMQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  33
• 可旋转键数：
  0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3β-hydroxy olean-11-en-28->13 oate 在 双氧水 、 对甲苯磺酸 作用下， 反应 10.0h， 以80%的产率得到11alpha,12alpha-环氧-3beta,13-二羟基齐墩果烷-28-酸 gamma-内酯
  参考文献：
  名称：

  Yoshikawa, Masayuki; Wang, Hui Kang; Tosirisuk, Veeraphan, Chemical and pharmaceutical bulletin, 1982, vol. 30, # 8, p. 3057 - 3060

  摘要：

  DOI：
• 作为产物：
  描述：

  齐墩果酸 以 甲醇 、 溶剂黄146 为溶剂， 反应 8.0h， 以92%的产率得到3β-hydroxy olean-11-en-28->13 oate
  参考文献：
  名称：

  Yoshikawa, Masayuki; Wang, Hui Kang; Tosirisuk, Veeraphan, Chemical and pharmaceutical bulletin, 1982, vol. 30, # 8, p. 3057 - 3060

  摘要：

  DOI：

文献信息

• Triterpenoids, essential oil and photo-oxidative 28 → 13-lactonization of oleanolic acid from Lantana camara
  作者：Laxminarain Misra、Hartmut Laatsch

  DOI：10.1016/s0031-9422(00)00131-x

  日期：2000.8

  Two novel triterpenoids have been isolated from the roots of Lantana camara L.: 3 beta,19 alpha dihydroxy ursan-28-oic acid and 21,22 beta- epoxy-3 beta-hydroxy olean-12-en-28-oic acid in its methyl ester form. Its leaves have yielded an essential oil which is rich in sesquiterpenes. Oleanolic acid, which is thought to be a hepatoprotective compound, was isolated from L. camara roots and converted into its 28 --> 13 beta lactone by a facile photo-oxidation reaction. (C) 2000 Elsevier Science Ltd. All rights reserved.
• Oleanane benzoates from the bark of Ploiarium alternifolium
  作者：Graham J Bennett、Leslie J Harrison、Guat-Lee Sia、Keng-Yeow Sim、Joseph D Connolly

  DOI：10.1016/0031-9422(92)80283-k

  日期：1992.4

  Two triterpenoid benzoates, 3-beta-benzoyloxyoleana-11,13(18)-dien-28-oic acid, characterized as its methyl ester, and 3-beta-benzoyloxyolean-11-en-13-beta,28-olide have been isolated from the bark of Ploiarium alternifolium. Their structures were determined by spectroscopic methods and by chemical correlation with known compounds.
• PEREDA-MIRANDA, ROGELLO;DELGADO, GUILLERMO, J. NATUR. PROD., 53,(1990) N, C. 182-185
  作者：PEREDA-MIRANDA, ROGELLO、DELGADO, GUILLERMO

  DOI：——

  日期：——
• Yoshikawa, Masayuki; Wang, Hui Kang; Tosirisuk, Veeraphan, Chemical and pharmaceutical bulletin, 1982, vol. 30, # 8, p. 3057 - 3060
  作者：Yoshikawa, Masayuki、Wang, Hui Kang、Tosirisuk, Veeraphan、Kitagawa, Isao

  DOI：——

  日期：——