8-Methoxy-isoflavon | 5832-16-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 8-Methoxy-isoflavon
• 英文别名: 8-methoxy-3-phenyl-4H-chromen-4-one；8-methoxy-3-phenylchromen-4-one
• CAS: 5832-16-6
• 化学式: C₁₆H₁₂O₃
• 分子量: 252.269
• InChiKey: VUWMTIBHTJZLON-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  8-Methoxy-isoflavon 在 Br^(1-)*C₁₀H₁₈N₅O₂⁽¹⁺⁾ 、 双氧水 、 sodium hydroxide 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 以89%的产率得到
  参考文献：
  名称：

  A novel L-asparaginyl Amido ethyl methyl imidazolium bromide catalyst for heterogeneous epoxidation of α, β-unsaturated ketones

  摘要：

  In the present work, a class of imidazolium based ionic liquid coupled with asparagine system was employed for asymmetric epoxidation. The heterogeneous catalyst exhibited excellent activity for epoxidation of alpha, beta-unsaturated ketones, affording the corresponding epoxy ketones in the presence of hydrogen peroxide. The catalyst was easily recovered from the reaction mixture and reused for five consecutive runs. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molliq.2012.05.016

文献信息

• A novel L-asparaginyl Amido ethyl methyl imidazolium bromide catalyst for heterogeneous epoxidation of α, β-unsaturated ketones
  作者：Parasuraman Karthikeyan、Aswar Sachin Arunrao、Muskawar Prashant Narayan、Sythana Suresh Kumar、S. Senthil Kumar、Pundlik Rambhau Bhagat

  DOI：10.1016/j.molliq.2012.05.016

  日期：2012.8

  In the present work, a class of imidazolium based ionic liquid coupled with asparagine system was employed for asymmetric epoxidation. The heterogeneous catalyst exhibited excellent activity for epoxidation of alpha, beta-unsaturated ketones, affording the corresponding epoxy ketones in the presence of hydrogen peroxide. The catalyst was easily recovered from the reaction mixture and reused for five consecutive runs. (C) 2012 Elsevier B.V. All rights reserved.