(4R)-1-methyl-4-[(1R,S)-1-methyl-2-(phenylsilyl)ethyl]cyclohex-1-ene

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (4R)-1-methyl-4-[(1R,S)-1-methyl-2-(phenylsilyl)ethyl]cyclohex-1-ene
• 英文别名: 2-[(1R)-4-methylcyclohex-3-en-1-yl]propyl-phenylsilane
• 化学式: C₁₆H₂₄Si
• 分子量: 244.452
• InChiKey: RWTMRIFABAEYCY-LOACHALJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.28
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  甜橙提取物 、 苯硅烷 在 (C₅Me₅)(ⁱPr₂MeP)H₂FeH(N₂) 、 三苯碳四(五氟苯基)硼酸盐 作用下， 以 氟苯 为溶剂， 反应 20.0h， 以92%的产率得到(4R)-1-methyl-4-[(1R,S)-1-methyl-2-(phenylsilyl)ethyl]cyclohex-1-ene
  参考文献：
  名称：

  Efficient and selective alkene hydrosilation promoted by weak, double Si–H activation at an iron center

  摘要：

  阳离子铁配合物[Cp*(ⁱPr₂MeP)FeH₂SiHR]⁺在溶液中生成并表征，对末端烯烃和内部炔烃的氢硅烷化反应具有很高的催化效率，且在低催化剂负载量（0.1 mol%）和室温下表现出良好的催化活性。

  DOI：

  10.1039/d0sc01749c

文献信息

• A β-diketiminate manganese catalyst for alkene hydrosilylation: substrate scope, silicone preparation, and mechanistic insight
  作者：Tufan K. Mukhopadhyay、Marco Flores、Thomas L. Groy、Ryan J. Trovitch

  DOI：10.1039/c8sc02768d

  日期：——

  A (BDI)Mn catalyst has been found to hydrosilylate olefins and the observed selectivity can be attributed to alkene insertion.

  一种（BDI）Mn催化剂已被发现可以对烯烃进行氢硅化反应，观察到的选择性可以归因于烯烃插入。
• Organometallic compounds of the lanthanides. CXXIII. Lanthanide bent-sandwich complexes with the bulky tetramethyl-iso-propylcyclopentadienyl ligand—synthesis, structures and catalytic activity for the hydrosilylation of alkenes/alkynes
  作者：Herbert Schumann、Markus R. Keitsch、Jörn Winterfeld、Stefan Mühle、Gary A. Molander

  DOI：10.1016/s0022-328x(98)00410-0

  日期：1998.5

  [(η5-C5Me4 iPr)2Ln(THF)] (Ln=Sm (8), Yb (9)). The new compounds with the bulky tetramethyl-iso-propylcyclopentadienyl ligands were characterized by C, H analysis, mass spectrometry and NMR spectroscopy. Additionally, single crystal X-ray structure determination of the lutetium complexes 3 and 5 was performed. It has been shown that the alkyl complexes 4–7 are effective precatalysts for the hydrosilylation

  钇，钐和镥的三氯化物用Na两个当量反应[C 5我4 我镨]在THF中的形式[（η 5 -C 5我4 我PR）2 LnCl（THF）]（Ln为Y（1），Sm（2），Lu（3））。的复分解1 - 3与的LiCH 3在乙醚和的LiCH（森达3）2在甲苯中给出[（η 5 -C 5我4 我PR）2 LnCH 3（THF）]（Ln为Y（4），路（5））和[（η 5 -C 5我4 我PR）2 LN CH（森达3）2 }]（Ln为Y（6），钐（7分别地）），。1：LNI 2反应2（THF）X（LN = SM，Yb）的用Na [C 5我4 我镨]在二价金属茂的形成THF结果[（η 5 -C 5我4 我镨）2 Ln（THF）]（Ln = Sm（8），Yb（9））。与四甲基笨重的新化合物异由C，H分析，质谱和NMR光谱-propylcyclopentadienyl配体进行了表征。另外，进行the络合物3和5的
• Iron-Catalysed Chemo-, Regio-, and Stereoselective Hydrosilylation of Alkenes and Alkynes using a Bench-Stable Iron(II) Pre-Catalyst
  作者：Mark D. Greenhalgh、Dominik J. Frank、Stephen P. Thomas

  DOI：10.1002/adsc.201300827

  日期：2014.2.10

  AbstractThe chemo‐, regio‐, and stereoselective iron‐catalysed hydrosilylation of alkenes and alkynes with excellent functional group tolerance is reported (34 examples, 41–96% yield). The catalyst and reagents are commercially available and easy to handle, with the active iron catalyst being generated in situ, thus providing a simple and practical methodology for iron‐catalysed hydrosilylation. The silane products can be oxidised to the anti‐Markovnikov product of olefin hydration, and the one‐pot iron‐catalysed hydrosilylation–oxidation of olefins to give silane(di)ols directly is also reported. The iron pre‐catalyst was used at loadings as low as 0.07 mol%, and displayed catalyst turnover frequencies (TOF) approaching 60,000 mol h−1. Initial mechanistic studies indicate an iron(I) active catalyst.magnified image
• Selective hydrosilylation of alkenes catalyzed by an organoyttrium complex
  作者：Gary A. Molander、Manfred Julius

  DOI：10.1021/jo00049a056

  日期：1992.11
• Efficient and selective alkene hydrosilation promoted by weak, double Si–H activation at an iron center
  作者：Patrick W. Smith、Yuyang Dong、T. Don Tilley

  DOI：10.1039/d0sc01749c

  日期：——

  Cationic iron complexes [Cp*(ⁱPr₂MeP)FeH₂SiHR]⁺, generated and characterized in solution, are very efficient catalysts for the hydrosilation of terminal alkenes and internal alkynes by primary silanes at low catalyst loading (0.1 mol%) and ambient temperature.

  阳离子铁配合物[Cp*(ⁱPr₂MeP)FeH₂SiHR]⁺在溶液中生成并表征，对末端烯烃和内部炔烃的氢硅烷化反应具有很高的催化效率，且在低催化剂负载量（0.1 mol%）和室温下表现出良好的催化活性。