十二烷酸,2,6,10-三甲基-(9CI) | 168254-98-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 中文名称: 十二烷酸,2,6,10-三甲基-(9CI)
• 英文名称: mangfarnasoic acid
• 英文别名: 2,6,10-Trimethyldodecanoic acid
• CAS: 168254-98-6
• 化学式: C₁₅H₃₀O₂
• 分子量: 242.402
• InChiKey: QSRPPMDQXUXZAD-UHFFFAOYSA-N

物化性质

• 沸点：
  349.9±10.0 °C(Predicted)
• 密度：
  0.891±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6
• 重原子数：
  17
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 十二烷酸,2,6,10-三甲基-(9CI) 以 乙醚 为溶剂， 反应 0.5h， 生成 (2R/S,6R/S,10R/S)-methyl-2,6,10-trimethyldodecanoate
  参考文献：
  名称：

  摘要：

  Methyl 2,6,10-trimethyltridecanoate (1) and methyl 2,6,10-trimethyldodecanoate (2) have been identified as male-produced sex pheromones of the Brazilian soybean stink bugs Euschistus heros (F.) and Piezodorus guildinii (Westwood). In order to establish a defined attractive blend for both species, compounds 1 and 2 were synthesized as mixtures of stereoisomers to be employed in behavior bioassays. (+/-)-Citronellol (3) was utilized as starting material. and the syntheses was carried out in six steps with good overall yield. When tested alone, synthetic compounds 1 and 2 proved to be active in a two-choice olfactometer: however, a 20:1 mixture of 1 and 2 was much more attractive to E. heros females. A similar blend had been found among the headspace volatiles of males.

  DOI：

  10.1023/a:1026433608967
• 作为产物：
  描述：

  2-甲基丁醇 在 platinum(IV) oxide chromium(VI) oxide 、 叔丁基过氧化氢 、 sodium tetrahydroborate 、 selenium(IV) oxide 、 溴 、 magnesium 、 三苯基膦 、 水杨酸 作用下， 以 四氢呋喃 、 甲醇 、 正己烷 、 二氯甲烷 、 丙酮 为溶剂， -5.0~20.0 ℃ 、172.37 kPa 条件下， 反应 37.75h， 生成 十二烷酸,2,6,10-三甲基-(9CI)
  参考文献：
  名称：

  摘要：

  Methyl 2,6,10-trimethyltridecanoate (1) and methyl 2,6,10-trimethyldodecanoate (2) have been identified as male-produced sex pheromones of the Brazilian soybean stink bugs Euschistus heros (F.) and Piezodorus guildinii (Westwood). In order to establish a defined attractive blend for both species, compounds 1 and 2 were synthesized as mixtures of stereoisomers to be employed in behavior bioassays. (+/-)-Citronellol (3) was utilized as starting material. and the syntheses was carried out in six steps with good overall yield. When tested alone, synthetic compounds 1 and 2 proved to be active in a two-choice olfactometer: however, a 20:1 mixture of 1 and 2 was much more attractive to E. heros females. A similar blend had been found among the headspace volatiles of males.

  DOI：

  10.1023/a:1026433608967

文献信息

• Sharma, S. K.; Ali, M., Journal of the Indian Chemical Society, 1995, vol. 72, # 5, p. 339 - 342
  作者：Sharma, S. K.、Ali, M.

  DOI：——

  日期：——
• Extracts of Curcuma and Methods of Use Thereof
  申请人：Alberte Randall S.

  公开号：US20100098788A1

  公开（公告）日：2010-04-22

  The present invention relates in part to turmeric extracts that are useful for treating or preventing neurodegenerative disorders. Another aspect of the invention relates in part to turmeric extracts that are useful for treating or preventing inflammatory disorders. In some embodiments, the extracts comprise at least one compound selected from the group consisting of 25 to 500 μg bamosamine, 25 to 750 μg echinaxanthol, 100 to 3,000 μg bisdemethoxycurcumin, 50 to 500 μg daphniyunnine E and 500 to 75,000 μg curcumin per 100 mg of extract. Another aspect of the invention relates to pharmaceutical compositions comprising the aforementioned extracts. Another aspect of the invention relates to methods of treating or preventing neurodegenerative disorders comprising administering to a subject in need thereof an effective amount of the aforementioned extracts or compositions. Another aspect of the invention relates to methods of making the aforementioned extracts.
• ——
  作者：Paulo H. G. Zarbin

  DOI：10.1023/a:1026433608967

  日期：——

  Methyl 2,6,10-trimethyltridecanoate (1) and methyl 2,6,10-trimethyldodecanoate (2) have been identified as male-produced sex pheromones of the Brazilian soybean stink bugs Euschistus heros (F.) and Piezodorus guildinii (Westwood). In order to establish a defined attractive blend for both species, compounds 1 and 2 were synthesized as mixtures of stereoisomers to be employed in behavior bioassays. (+/-)-Citronellol (3) was utilized as starting material. and the syntheses was carried out in six steps with good overall yield. When tested alone, synthetic compounds 1 and 2 proved to be active in a two-choice olfactometer: however, a 20:1 mixture of 1 and 2 was much more attractive to E. heros females. A similar blend had been found among the headspace volatiles of males.