2-乙酰毛蕊花糖苷 | 94492-24-7

• 物质功能分类: 生物化工 - 提取物 - 植物提取物
• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 肉桂酸及其衍生物
• 中文名称: 2-乙酰毛蕊花糖苷
• 中文别名: 2-乙酰基洋丁香酚苷；2-乙酰基毛蕊花糖苷；2'-乙酰基毛蕊花糖苷；2'-乙酰毛蕊花糖苷；-乙酰毛蕊花糖苷；-乙酰基毛蕊花糖苷；2’-乙酰基毛蕊花糖苷；2-乙酰基麦角甾苷；-乙酰乳糖
• 英文名称: 2'-acetylacteoside
• 英文别名: 2′-acetylacteoside；2-Acetylacteoside；[(2R,3R,4S,5R,6R)-5-acetyloxy-6-[2-(3,4-dihydroxyphenyl)ethoxy]-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
• CAS: 94492-24-7
• 化学式: C₃₁H₃₈O₁₆
• 分子量: 666.633
• InChiKey: ALERZNQPBWWLMW-OMRKUVHCSA-N

物化性质

• 溶解度：
  溶于甲烷

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  47
• 可旋转键数：
  13
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  251
• 氢给体数：
  8
• 氢受体数：
  16

安全信息

• WGK Germany：
  3
• 储存条件：
  室温

制备方法与用途

生物活性方面，2'-Acetylacteoside 是一种从来江藤中分离得到的苯乙醇苷类化合物，能够抑制自由基诱导的红细胞溶血，并具有清除自由基的活性。

化学性质上，该物质为白色结晶粉末，可溶于甲醇、乙醇和DMSO等有机溶剂，来源于肉苁蓉。

用途方面，2-乙酰基毛蕊花糖苷具有清肠通便、强筋健髓的作用。此外，它还可用于含量测定、鉴定以及药理实验等。

反应信息

• 作为反应物：
  描述：

  乙酸酐 、 2-乙酰毛蕊花糖苷 以 吡啶 为溶剂， 以75 mg的产率得到verbascoside nonaacetate
  参考文献：
  名称：

  Kobayashi, Hiromi; Karasawa, Hiroko; Miyase, Toshio, Chemical and pharmaceutical bulletin, 1984, vol. 32, # 10, p. 3880 - 3885

  摘要：

  DOI：

文献信息

• Identification and occurrence of phenylethanoid and iridoid glycosides in six Polish broomrapes (Orobanche spp. and Phelipanche spp., Orobanchaceae)
  作者：Dariusz Jedrejek、Sylwia Pawelec、Renata Piwowarczyk、Łukasz Pecio、Anna Stochmal

  DOI：10.1016/j.phytochem.2019.112189

  日期：2020.2

  There are about 200 holoparasitic broomrapes (Orobanchaceae) known worldwide, however, only several species have been so far investigated phytochemically. Among Orobanche s.l. are both rare and endangered species, as well as onerous crop pests. This study aims to give a phytochemical description, both qualitative and quantitative, of six broomrape species (Orobanche and Phelipanche taxa) growing in Poland, including species that have not been tested in detail (O. caryophyllacea, O. linen, O. picridis, and P. arenaria). Sixteen metabolites, including 14 phenylethanoid glycosides (PhGs) and 2 iridoid glycosides (IrGs), were isolated and identified using NMR spectroscopy and hydrolysis, revealing the presence of two previously undescribed PhGs in P. ramosa, named ramoside A and 2'-acetylramoside A. In addition, in the example of O. caryophyllacea, we have reported as the first occurrence of IrGs in broomrapes. Concentrations of phenylethanoids, the main constituents of broomrapes, in the studied plant material (flowering shoots with haustoria) were determined using the UHPLC-PDA method. It was found that P. ramosa has been the richest source of PhGs. In addition, the differences between broomrapes have been visualized using principal component and cluster analysis. The results of the antiradical DPPH test of 13 PhGs confirmed previous findings on the relation of the antioxidant potential with the structure of phenolic moieties - phenolic acid and phenylethanoid unit.
• Kobayashi, Hiromi; Karasawa, Hiroko; Miyase, Toshio, Chemical and pharmaceutical bulletin, 1984, vol. 32, # 10, p. 3880 - 3885
  作者：Kobayashi, Hiromi、Karasawa, Hiroko、Miyase, Toshio、Fukushima, Seigo

  DOI：——

  日期：——