2-氨基-5-硝基苯磺酸 | 96-75-3

• 物质功能分类: 有机原料 - 氨基化合物 - 磺酸类氨基化合物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-氨基-5-硝基苯磺酸
• 中文别名: 4-硝基苯胺-2-磺酸；对硝基苯胺邻磺酸；对硝基苯胺-2-磺酸
• 英文名称: 2-amino-5-nitro-benzenesulfonic acid
• 英文别名: 4-nitroaniline-2-sulfonic acid；2-Amino-5-nitrobenzenesulfonic acid
• CAS: 96-75-3
• 化学式: C₆H₆N₂O₅S
• mdl: MFCD00035755
• 分子量: 218.19
• InChiKey: LTASFWDWBYFZQQ-UHFFFAOYSA-N

物化性质

• 熔点：
  196 °C(Solv: water (7732-18-5))
• 密度：
  1.559 (estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  135
• 氢给体数：
  2
• 氢受体数：
  6

安全信息

• 海关编码：
  2921420090
• 危险性防范说明：
  P280,P305+P351+P338
• 危险性描述：
  H302
• 储存条件：
  2-8°C

制备方法与用途

用途：用作染料中间体

反应信息

• 作为反应物：
  描述：

  2-氨基-5-硝基苯磺酸 在 硫酸 作用下， 反应 20.0h， 生成
  参考文献：
  名称：

  水溶性アゾ化合物又はその塩、インク組成物及び着色体

  摘要：

  【课题】提供一种水溶性黄色色素（化合物），特别是耐光性的水溶性黄色色素，它具有高水溶性、耐水性、耐湿性、耐臭氧性、耐擦性和耐光性等各种坚固性能，以及包含该色素的各种记录用，尤其是喷墨记录用的黄色墨水组成物，以及使用该墨水组成物着色的色体。 【解决手段】式（1）表示的水溶性偶氮化合物或其盐。 [R1～R4分别为H、卤素原子、羧基、羧甲基、磺基、磺甲氧基、羟基、氨基、氰基、磷酰基、硝基、乙酰基、（C1～C4）烷基、（C1～C4）环氧化、（C1～C4）磺烷基、（C1～C4）硫代烷基、（C1～C4）烷硫基或乙硫基；R5～R10为卤素原子或电子吸引性取代基；X为桥基] 【选择图】无

  公开号：

  JP2016098274A
• 作为产物：
  描述：

  6-硝基苯并噻唑 在 [RuCl(P(C₆H₅)3)2(O(C₆H₄)NCH(C₄H₃N))] 、 bromamine B 、 sodium hydroxide 作用下， 以 水 、 乙腈 为溶剂， 反应 5.75h， 以90%的产率得到2-氨基-5-硝基苯磺酸
  参考文献：
  名称：

  Development of an efficient ruthenium catalyzed synthetic process and mechanism for the facile conversion of benzothiazoles to orthanilic acids

  摘要：

  Ruthenium-Schiff base complex catalyzed efficient protocol has been developed for the synthesis of orthanilic acids from benzothiazoles in good to excellent yields using N-haloamines. Hexa-coordinated ruthenium complex with Schiff base and triphenylphosphine ligands has been prepared and its catalytic function was invented for the synthesis of orthanilic acids. The synthetic process utilizes our efficient method for the selective and preferential oxidation of thiazole ring of benzothiazoles using N-haloamines without effecting phenyl ring. The detailed catalytic, mechanistic and kinetic investigations have been made for the synthetic reactions. Solvent isotope studies have been made in H2O-D2O and the reactions were carried out at different temperatures. Under the identical set of conditions, the kinetics of catalyzed reactions has been compared with uncatalyzed reactions and found that the catalyzed reactions are 9-11 folds faster. The catalytic constants (K-c) have been calculated for each N-haloamine at different temperatures and the values of activation parameters with respect to the catalyst have been evaluated. Spectroscopic evidence for the formation of 1:1 complex between N-haloamine and ruthenium has been obtained. The observed results have been explained by a plausible mechanism and the related rate law has been deduced. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcata.2010.06.006

文献信息

• Black Trisazo Dyes, Their Preparation And Their Use
  申请人：DFI CHEM GmbH

  公开号：US20170335110A1

  公开（公告）日：2017-11-23

  The present invention provides trisazo dyes of formula (V), wherein A, M and R 1 , R 2 , R 3 , R 4 are as defined in the specification, processes for their preparation, recording liquids and liquid dye preparations containing them and their use in inks as well as processes for applying them and printed articles comprising them.

  本发明提供了式（V）的三偶氮染料，其中A、M和R1、R2、R3、R4如规范中所定义，其制备方法，含有它们的记录液体和液体染料制剂，以及它们在墨水中的使用方法以及应用它们的方法和包括它们的印刷品。
• [EN] WATER SOLUBLE AND WATER FAST DYES FOR INK JET PRINTING<br/>[FR] COLORANTS HYDROSOLUBLES ET SOLIDES À L'EAU POUR L'IMPRESSION PAR JET D'ENCRE
  申请人：ILFORD IMAGING CH GMBH

  公开号：WO2013139485A1

  公开（公告）日：2013-09-26

  The invention relates to azo dyes of desulfo-K-acid [CA: 35400-55-6], their salts, a method for the preparation of these dyes, or salts thereof, a liquid phase comprising at least one of these dyes, a method for applying the liquid phase on a substrate, a printed matter and the use of these dyes in water-based inks for inkjet printing, in writing utensil or dyeing solutions for manufacturing color filters for optical and opto-electronic applications.

  本发明涉及去磺酸K酸偶氮染料[CA: 35400-55-6]，它们的盐，制备这些染料或其盐的方法，至少包含一种这些染料的液相，将液相施加到基底上的方法，印刷品以及这些染料在水基喷墨打印油墨、书写工具或用于制造用于光电子应用的彩色滤光片的染色溶液中的用途。
• [EN] COMPOSITIONS AND INKS CONTAINING DISAZO DYES<br/>[FR] COMPOSITIONS ET ENCRES CONTENANT DES DISAZOIQUES
  申请人：AVECIA LTD

  公开号：WO2003104332A1

  公开（公告）日：2003-12-18

  A process for printing an image on a substrate comprising applying thereto a composition comprising a liquid medium and a compound of Formula (1) A-N=N-L-N=N-A wherein: each A independently is optionally substituted aryl or heteroaryl; and L is an optionally substituted, optionally metallised 1,8-dihydroxynaphthylene group; provided that: (i) at most one of the groups represented by A has a hydroxy substituent ortho to the -N=N- groups shown in Formula (1); and (ii) Formula (1) is not: Also claimed are compositions for printing, compounds and processes for making the compounds.

  一种在基材上印刷图像的过程，包括向其施加一种包含液体介质和公式(1)化合物的组成物：A-N=N-L-N=N-A，其中：每个A独立的是可选取代的芳基或杂芳基；L是1,8-二羟基萘基团，可选地被取代，可选地金属化；前提是：(i)在由A表示的组中，最多只有一个组在公式(1)所示的-N=N-基团邻位具有羟基取代基；且(ii)公式(1)不是：还要求保护印刷用组成物、化合物以及制造化合物的过程。
• [EN] A METHOD OF INHIBITING HEPATITIS C VIRUS BY COMBINATION OF A 5,6-DIHYDRO-1H-PYRIDIN-2-ONE AND ONE OR MORE ADDITIONAL ANTIVIRAL COMPOUNDS<br/>[FR] PROCÉDÉ D'INHIBITION DU VIRUS DE L'HÉPATITE C PAR COMBINAISON D'UNE 5,6-DIHYDRO-1H-PYRIDIN-2-ONE ET D'UN OU PLUSIEURS COMPOSÉS ANTIVIRAUX SUPPLÉMENTAIRES
  申请人：ANADYS PHARMACEUTICALS INC

  公开号：WO2010042834A1

  公开（公告）日：2010-04-15

  The invention is directed to a method of treating infections by hepatitis C virus by administering N-3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1 -dioxo-l,4-dihydro-lλ6- benzo[l,2,4]thiadiazin-7-yl} -methanesulfonamide and one or more additional antiviral compounds or pharmaceutical compositions containing such compounds.

  本发明涉及一种治疗乙型肝炎病毒感染的方法，通过给予N-3-[(1R,2S,7R,8S)-3-(4-氟苯基)-6-羟基-4-氧代-3-氮杂三环[6.2.1.02,7]十一碳-5-烯-5-基]-1,1-二氧代-1,4-二氢-1λ6-苯并[1,2,4]噻二唑-7-基}-甲磺酰胺以及一个或多个附加的抗病毒化合物或含有此类化合物的药物组合物。
• Dyes That are Soluble in Organic Solvents
  申请人：Ruch Thomas

  公开号：US20080184497A1

  公开（公告）日：2008-08-07

  The present invention relates to dyes of formula (1) that are soluble in organic solvents, wherein Cat + is an organic cation, to a process for their preparation and to their use in the production of coloured plastics or polymeric colour particles, printing colorants, printing pastes and printing inks.

  本发明涉及式(1)的染料，其在有机溶剂中可溶，其中Cat+是有机阳离子，还涉及它们的制备方法及其在有色塑料或聚合物彩色颗粒、印花着色剂、印花浆和印刷油墨生产中的用途。