5-methoxy-3-(4-methoxy-phenyl)-8-methyl-chromen-4-one | 85541-07-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 异黄酮类化合物
• 英文名称: 5-methoxy-3-(4-methoxy-phenyl)-8-methyl-chromen-4-one
• 英文别名: 5-Methoxy-3-(4-methoxy-phenyl)-8-methyl-chromen-4-on；5-Methoxy-3-(4-methoxyphenyl)-8-methylchromen-4-one
• CAS: 85541-07-7
• 化学式: C₁₈H₁₆O₄
• 分子量: 296.323
• InChiKey: KQRITWMPZPRHMC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  5-methoxy-3-(4-methoxy-phenyl)-8-methyl-chromen-4-one 在 氢碘酸 、 乙酸酐 作用下， 生成 daidzein
  参考文献：
  名称：

  345. 5：4'-二羟基-8-甲基异黄酮，和上lotoflavin记

  摘要：

  DOI：

  10.1039/jr9570001833
• 作为产物：
  描述：

  甲酸乙酯 、 alkaline earth salt of/the/ methylsulfuric acid 在 sodium 作用下， 生成 5-methoxy-3-(4-methoxy-phenyl)-8-methyl-chromen-4-one
  参考文献：
  名称：

  345. 5：4'-二羟基-8-甲基异黄酮，和上lotoflavin记

  摘要：

  DOI：

  10.1039/jr9570001833

文献信息

• GLUCOPYRANOSIDE, PROCESS FOR ISOLATION THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND USE THEREOF
  申请人：COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH

  公开号：EP1495019B1

  公开（公告）日：2008-07-02
• NOVEL GLUCOPYRANOSIDE, PROCESS FOR ISOLATION THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND USE THEREOF
  申请人：COUNCIL OF SCIENTIFIC ANDINDUSTRIAL RESEARCH

  公开号：EP1495019A1

  公开（公告）日：2005-01-12
• [EN] NOVEL GLUCOPYRANOSIDE, PROCESS FOR ISOLATION THEREOF, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND USE THEREOF<br/>[FR] NOUVEAU GLUCOPYRANOSIDE, SON PROCEDE D'ISOLATION, COMPOSITION PHARMACEUTIQUE CONTENANT LEDIT GLUCOPYRANOSIDE
  申请人：COUNCIL SCIENT IND RES

  公开号：WO2003087093A1

  公开（公告）日：2003-10-23

  A novel glucopyranoside, 6-hydroxy-2-p-hydroxybenzylbenzofuran-7-C-β-D-glucopyranoside of the formula (1) isolated from Pterocarpus marsupium and to a process for the isolation thereof is disclosed. The invention also relates to a pharmaceutical composition containing 6-hydroxy-2-p-hydroxybenzylbenzofuran-7-C-β-D-glucopyranoside and to method for the treatment of diabetes using said compound.
• [EN] NOVEL GLUCOPYRANOSIDE AND A PROCESS OF ISOLATION THEREOF FROM PTEROCARPUS MARSUPIUM PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND USE THEREOF<br/>[FR] NOUVEAU GLUCOPYRANOSIDE ET PROCEDE PERMETTANT D'ISOLER CETTE SUBSTANCE A PARTIR DE PTEROCARPUS MARSUPIUM. COMPOSITION PHARMACEUTIQUE RENFERMANT CETTE SUBSTANE ET SON UTILISATION
  申请人：COUNCIL SCIENT IND RES

  公开号：WO2003080634A1

  公开（公告）日：2003-10-02

  A novel glucopyranoside, 2, 6 - dihydroxy -2 - (P -hydroxybenzyl) - 3 (2H) benzofuran-7-c-β-D-glucopyranoside of the formula 1 isolated from Pterocarpus marsupium and to a process for the isolation thereof is disclosed. The invention also relates to a pharmaceutical composition containing 2, 6 - dihydroxy -2- (P -hydroxybenzyl) - 3(2H) benzofuran -7 -C -β -D - glucopyranoside and to method for the treatment of diabetes using said compound.