4-(2-羟基-1-甲氧基乙基)-1,2-苯二酚 | 577976-26-2

• 物质功能分类: 天然产物 - 酚类
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-(2-羟基-1-甲氧基乙基)-1,2-苯二酚
• 英文名称: 2-<3',4'-dihydroxyphenyl>-2-methoxyethanol
• 英文别名: 3,4-dihydroxy-β-methoxyphenethyl alcohol；3,4-Dihydroxy-β-methoxy-phenaethylalkohol；(+/-)-4-(2-Hydroxy-1-methoxy-aethyl)-brenzcatechin；(+/-)-1-Methoxy-1-(3,4-dihydroxy-phenyl)-aethanol-(2)；(+/-)-3,4-Dihydroxy-1-(2-hydroxy-1-methoxy-aethyl)-benzol；2-methoxy-2-(3,4-dihydroxy-phenyl)ethanol；4-(2-Hydroxy-1-methoxyethyl)benzene-1,2-diol
• CAS: 577976-26-2
• 化学式: C₉H₁₂O₄
• 分子量: 184.192
• InChiKey: YWTLCGMGZCXRMS-UHFFFAOYSA-N

物化性质

• 溶解度：
  溶于氯仿、二氯甲烷、乙酸乙酯、DMSO、丙酮等。

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  69.9
• 氢给体数：
  3
• 氢受体数：
  4

安全信息

• 海关编码：
  2909499000

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 4-(2-羟基-1-甲氧基乙基)-1,2-苯二酚 在 甲醇 作用下， 生成 2-Methoxy-2-<3,4-dimethoxy-phenyl>-aethanol
  参考文献：
  名称：

  Demonstrating Effectiveness of Passive Radon-Resistant New Construction

  摘要：

  Fifty percent of homes tested for radon in Rock Island County, IL, have radon levels above the U.S. Environmental Protection Agency (EPA) action guideline of 4 picoCuries per liter (pCi/L) of air. Therefore, the county is classified by the EPA as Zone 1 on the EPA's Map of Radon Potential. Radon-resistant new construction (RRNC) strategies for new homes are recommended by the EPA in Zone 1 areas. One city in the county, East Moline, reduced the cost of building permits for contractors volunteering to build new homes incorporating modified passive RRNC. Forty-six of 124 new homes built with passive RRNC in the city were tested during this study. Only 27 of the homes tested were below 4-pCi/L, justifying the importance of testing the system to ensure levels are below the action guideline. To provide additional support to an argument in favor of changing city building codes to the required RRNC, 23 of the homes were also tested with the systems deactivated. After systems were deactivated, 73% of the homes had radon levels above the action guideline. Four homes were sampled for bioaerosols to evaluate if passive RRNC might impact other indicators of poor indoor air quality (IAQ). The results of the research will be discussed here.

  DOI：

  10.1080/10473289.2001.10464256
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 甲醇 、 sodium methylate 作用下， 生成 4-(2-羟基-1-甲氧基乙基)-1,2-苯二酚
  参考文献：
  名称：

  Demonstrating Effectiveness of Passive Radon-Resistant New Construction

  摘要：

  Fifty percent of homes tested for radon in Rock Island County, IL, have radon levels above the U.S. Environmental Protection Agency (EPA) action guideline of 4 picoCuries per liter (pCi/L) of air. Therefore, the county is classified by the EPA as Zone 1 on the EPA's Map of Radon Potential. Radon-resistant new construction (RRNC) strategies for new homes are recommended by the EPA in Zone 1 areas. One city in the county, East Moline, reduced the cost of building permits for contractors volunteering to build new homes incorporating modified passive RRNC. Forty-six of 124 new homes built with passive RRNC in the city were tested during this study. Only 27 of the homes tested were below 4-pCi/L, justifying the importance of testing the system to ensure levels are below the action guideline. To provide additional support to an argument in favor of changing city building codes to the required RRNC, 23 of the homes were also tested with the systems deactivated. After systems were deactivated, 73% of the homes had radon levels above the action guideline. Four homes were sampled for bioaerosols to evaluate if passive RRNC might impact other indicators of poor indoor air quality (IAQ). The results of the research will be discussed here.

  DOI：

  10.1080/10473289.2001.10464256

文献信息

• COMPOUNDS AND COMPOSITIONS DERIVED FROM OLIVES AND METHODS OF USE THEREOF
  申请人：——

  公开号：US20030185921A1

  公开（公告）日：2003-10-02

  The preparation of extracts from olive fruits, olive tree leaves, olive oil as well as olive-press waste. The isolation of natural products from these extracts and the evaluation of the DNA protective antioxidant activity of the extracts and the purified compounds on intact cells.

  从橄榄果实、橄榄树叶、橄榄油以及橄榄压榨废弃物中提取物质。从这些提取物中分离天然产物，并评估提取物和纯化化合物对完整细胞的DNA保护抗氧化活性。
• USE OF COMPOUNDS AND COMPOSITIONS DERIVED FROM OLIVES FOR PROTECTING CELLS AGAINST DNA DAMAGE
  申请人：LAVIPHARM S.A.

  公开号：EP1474130A2

  公开（公告）日：2004-11-10
• US6906100B2
  申请人：——

  公开号：US6906100B2

  公开（公告）日：2005-06-14
• [EN] COMPOUNDS AND COMPOSITIONS DERIVED FROM OLIVES AND METHODS OF USE THEREOF<br/>[FR] COMPOSES ET COMPOSITIONS TIRES D'OLIVES ET METHODES D'UTILISATION
  申请人：LAVIPHARM SA

  公开号：WO2003066034A2

  公开（公告）日：2003-08-14

  Use of extracts from olive fruits, olive tree leaves, olive oil as well as olive -press waste for protecting cells from DNA damage. The evaluation of the DNA protective antioxidant activity of the extracts and the purified compounds on intact cells.
• [EN] BACTERIAL STRAINS AND THE USES THEREOF IN ACYLATION AND/OR DEACYLATION REACTIONS<br/>[ES] CEPAS BACTERIANAS Y SUS USOS EN REACCIONES DE ACILACIÓN Y/O DESACILACIÓN<br/>[FR] SOUCHES BACTÉRIENNES ET LEURS UTILISATIONS DANS DES REACTIONS D'ACYLATION ET/OU DÉSACYLATION
  申请人：UNIV SEVILLA

  公开号：WO2015169980A1

  公开（公告）日：2015-11-12

  La presente invención describe cepas microbianas con capacidad de llevar a cabo reacciones de alcoholisis y esterificación regioselectivas y el uso de las mismas en la producción de carbohidratos y polifenoles lipófilos de interés en la industria farmacéutica y alimentaria. Asimismo, la invención divulga el método de obtención de las cepas microbianas y el método de obtención de los carbohidratos y polifenoles lipofílicos.