硬脂酰基肌氨酸 | 142-48-3

• 物质功能分类: 有机原料 - 羧酸类化合物及衍生物
• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 硬脂酰基肌氨酸
• 中文别名: 硬脂酰肌氨酸
• 英文名称: N-stearoyl sarcosine
• 英文别名: N-methyl-N-stearoyl-glycine；N-Methyl-N-stearoyl-glycin；(Methyl-stearoyl-amino)-essigsaeure；N-Stearoyl-sarkosin；N-methyl-N-(1-oxooctadecyl)-glycine；N-(1-oxooctadecyl)sarcosine；Stearoyl sarcosine；2-[methyl(octadecanoyl)amino]acetic acid
• CAS: 142-48-3
• 化学式: C₂₁H₄₁NO₃
• 分子量: 355.561
• InChiKey: RJYOKYDKKOFLBT-UHFFFAOYSA-N

物化性质

• 熔点：
  65-66.5 °C
• 沸点：
  489.8±28.0 °C(Predicted)
• 密度：
  0.950±0.06 g/cm3(Predicted)
• LogP：
  7.294 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  7.7
• 重原子数：
  25
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  57.6
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 危险性防范说明：
  P264,P280,P302+P352,P337+P313,P305+P351+P338,P362+P364,P332+P313
• 危险性描述：
  H315,H319

反应信息

• 作为反应物：
  描述：

  硬脂酰基肌氨酸 、 四乙烯五胺 生成 N-[[1-[2-[2-(2-aminoethylamino)ethylamino]ethyl]-4,5-dihydroimidazol-2-yl]methyl]-N-methyloctadecanamide
  参考文献：
  名称：

  SUNG, R. L.;DORN, P.

  摘要：

  DOI：
• 作为产物：
  描述：

  sodium sarcosinate 、 十八烷酰氯 以 水 为溶剂， 反应 1.0h， 生成 硬脂酰基肌氨酸
  参考文献：
  名称：

  Iyer, Venkataraman N.; Sheth, Geeta N.; Subrahmanyam, V. V. R., Journal of the Indian Chemical Society, 1982, vol. 59, # 7, p. 856 - 859

  摘要：

  DOI：

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• COSMETIC COMPOSITION BASED ON A SUPRAMOLECULAR POLYMER AND A SILICONE COMPOUND
  申请人：L'OREAL

  公开号：US20140154196A1

  公开（公告）日：2014-06-05

  The present invention relates to a process for making up and/or caring for the skin and/or the lips, comprising the application to the skin and/or the lips of a cosmetic composition and in particular a composition for making up and/or caring for the skin and/or the lips, comprising at least one supramolecular polymer and a silicone compound with a viscosity of less than 10 000 000 cSt at 25° C.

  本发明涉及一种用于化妆和/或护理皮肤和/或嘴唇的方法，包括将化妆品组合物，特别是用于化妆和/或护理皮肤和/或嘴唇的组合物，施用到皮肤和/或嘴唇上，所述组合物包括至少一种超分子聚合物和一种粘度低于25°C时小于10,000,000 cSt的硅氧烷化合物。
• COSMETIC PROCESS FOR MAKING-UP AND/OR CARING FOR THE SKIN AND/OR THE LIPS
  申请人：L'OREAL

  公开号：US20150290116A1

  公开（公告）日：2015-10-15

  A cosmetic process for making-up and/or caring for skin and/or lips, includes the application to skin and/or lips of a cosmetic composition including, in a physiologically acceptable medium, at least one supramolecular polymer and at least one hydrophobic film-forming polymer. Particular compositions may be used in the process.

  一种化妆和/或护理皮肤和/或嘴唇的化妆过程，包括将至少一种超分子聚合物和至少一种疏水膜形成聚合物混合于生理可接受的介质中的化妆组合物涂抹到皮肤和/或嘴唇上。特定的组合物可用于该过程。
• INTERCALATED BLEACH COMPOSITIONS, RELATED METHODS OF MANUFACTURE AND USE
  申请人：THE CLOROX COMPANY

  公开号：US20170002300A1

  公开（公告）日：2017-01-05

  The invention relates to compositions, methods of use, and methods of manufacture for an intercalated bleach compound and compositions thereof. The intercalated bleach compound has the formula M x (OCl) y (O) m (OH) n where M is an alkaline earth metal such as magnesium, calcium or mixture thereof. The values of x and y independently equal any number greater than or equal to 1 (e.g., 1, 2, 3, 4, etc.), and m and n independently equal any number greater than or equal to 0 (e.g., 0, 1, 2, 3, 4, etc.), but m and n are not both 0. In addition, the molar ratio of the alkaline earth metal (e.g., magnesium or calcium) to hypochlorite is at least 3:1. In other words, x is ≧3y. The compounds exhibit excellent stability, little or no chlorine bleach odor, exhibit excellent pH buffering characteristics, and less reactivity with organic materials as compared to alternative chlorine bleach products.

  本发明涉及一种插层漂白剂化合物及其组成物的使用方法和制造方法。插层漂白剂化合物的化学式为Mx(OCl)y(O)m(OH)n，其中M是碱土金属，例如镁、钙或其混合物。x和y的值分别独立地等于大于或等于1的任意数字（例如1、2、3、4等），而m和n的值分别独立地等于大于或等于0的任意数字（例如0、1、2、3、4等），但m和n不能同时为0。此外，碱土金属（例如镁或钙）与次氯酸盐的摩尔比至少为3:1。换句话说，x≧3y。这些化合物表现出优异的稳定性，几乎没有氯漂白剂气味，表现出优异的pH缓冲特性，并且与有机材料相比，反应性更小。