(6,6-Dimethyl-2-bicyclo[3.1.1]hept-2-enyl)methyl-trimethylsilane | 66275-58-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 异戊烯醇脂质
• 英文名称: (6,6-Dimethyl-2-bicyclo[3.1.1]hept-2-enyl)methyl-trimethylsilane
• CAS: 66275-58-9
• 化学式: C₁₃H₂₄Si
• 分子量: 208.419
• InChiKey: BXDZLAZHACCTRG-UHFFFAOYSA-N

物化性质

• 沸点：
  234.6±19.0 °C(Predicted)
• 密度：
  0.863±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.32
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  (6,6-Dimethyl-2-bicyclo[3.1.1]hept-2-enyl)methyl-trimethylsilane 、 四甲基氢氧化铵 、 水 生成 六甲基二硅氧烷
  参考文献：
  名称：

  DELERIS G.; KAWALSKI J.; DUNOQUES J.; CALAS R., TETRAHEDRON LETT., 1977, NO 48, 4211-4214

  摘要：

  DOI：
• 作为产物：
  描述：

  (6,6-dimethyl-2-methylidene-3-bicyclo[3.1.1]heptanyl)sulfanyl-trimethylsilane 、 三甲基氯硅烷 以95%的产率得到
  参考文献：
  名称：

  DELERIS G.; KAWALSKI J.; DUNOQUES J.; CALAS R., TETRAHEDRON LETT., 1977, NO 48, 4211-4214

  摘要：

  DOI：

文献信息

• Silylation of Allylic Trifluoroacetates and Acetates Using Organodisilanes Catalyzed by Palladium Complex
  作者：Yasushi Tsuji、Masahiro Funato、Masakatsu Ozawa、Hiroaki Ogiyama、Satoshi Kajita、Takashi Kawamura

  DOI：10.1021/jo960345t

  日期：1996.1.1

  Silylation of allylic acetates (1) using organodisilanes (2) was carried out in the presence of a catalytic amount of Pd(DBA)2-LiCl at 100 degrees C. The silylation proceeded smoothly without beta-hydrogen elimination of. resulting (pi-allyl)palladium intermediate. The added chloride salt such as LiCl or NaCl was indispensable for the catalytic activity. On the other hand, remarkable improvement of the silylation was realized by employing allylic trifluoroacetates (4) in place of the acetates (1) as the substrates. The silylation proceeded even at room temperature, and the added chloride salts was not necessary as the catalyst component. In the silylation, transmetalation of the disilanes (2) with (eta(3)-allyl)palladium intermediate (7) might be a critical step in the catalytic cycle. Model reactions for the transmetalation were carried out.
• Palladium-catalyzed silylation of allylic acetates with hexamethyldisilane or (trimethylsilyl)tributylstannane
  作者：Yasushi Tsuji、Satoshi Kajita、Shinya Isobe、Masahiro Funato

  DOI：10.1021/jo00066a005

  日期：1993.7

  Various allylic acetates (1a-j) are silylated with hexamethyldisilane (Me3SiSiMe3, 2) in the presence of a catalytic amount of Pd(DBA)2 and LiCl at 100-degrees-C to afford the corresponding allylic silanes in high yields. In addition, (trimethylsilyl)tributylstannane (Me3SiSnBu3, 3) can be used for the silylation of aromatic allylic acetates 1g-j at room temperature.
• Tsuji Yasushi, Kajita Satoshi, Isobe Shinya, Funato Masahiro, J. Org. Chem., 58 (1993) N 14, S 3607-3608
  作者：Tsuji Yasushi, Kajita Satoshi, Isobe Shinya, Funato Masahiro

  DOI：——

  日期：——