1-amino-3-hexanone ethylene acetal | 130179-18-9

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1-amino-3-hexanone ethylene acetal
• 英文别名: 2-(2-Propyl-1,3-dioxolan-2-yl)ethanamine
• CAS: 130179-18-9
• 化学式: C₈H₁₇NO₂
• 分子量: 159.228
• InChiKey: MAVOWRGLQHTXSS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-amino-3-hexanone ethylene acetal 在 硫酸 、 三氟化硼乙醚 、 potassium tert-butylate 、 potassium carbonate 、 对甲苯磺酸 作用下， 以 四氢呋喃 、 乙醇 、 苯 为溶剂， 反应 48.0h， 生成 trans-1-ethyl-3,4,6,7,12,12b-hexahydro<2,3-a>quinolizin-2(1H)-one
  参考文献：
  名称：

  吲哚生物碱的合成研究。三，1-乙基吲哚并[2,3 - a ]喹啉zidin -2-one的合成

  摘要：

  1-ethylindolo的合成[2,3-一个] quinolizidin -2-酮3是由钾报道叔丁醇的环化Ñ羟乙基-2- [1-（苯基磺酰基）-3-吲哚基] -4-哌啶酮乙烯乙缩醛10，然后酸处理中间螺环亚胺8。

  DOI：

  10.1016/s0040-4039(00)97469-0
• 作为产物：
  描述：

  1-氯己烷-3-酮 在 对甲苯磺酸 、 一水合肼 作用下， 以 甲醇 、 N,N-二甲基甲酰胺 、 苯 为溶剂， 反应 50.0h， 生成 1-amino-3-hexanone ethylene acetal
  参考文献：
  名称：

  Studies on the synthesis of indolo[2,3-α]quinolizidin-2-ones. II

  摘要：

  DOI：

  10.1016/s0040-4020(01)86779-x

文献信息

• Synthetic studies on indole alkaloids. III. Synthesis of 1-ethylindolo[2,3-a]quinolizidin-2-one
  作者：Mario Rubiralta、Anna Diez、Cristina Vila

  DOI：10.1016/s0040-4039(00)97469-0

  日期：——

  The synthesis of 1-ethylindolo[2,3-a]quinolizidin-2-one 3 is reported by potassium tert-butoxide cyclization of N-hydroxyethyl-2-[1-(phenylsulfonyl)-3-indolyl]-4-piperidone ethylene acetal 10 followed by acid treatment of the intermediate spiroindolenines 8.

  1-ethylindolo的合成[2,3-一个] quinolizidin -2-酮3是由钾报道叔丁醇的环化Ñ羟乙基-2- [1-（苯基磺酰基）-3-吲哚基] -4-哌啶酮乙烯乙缩醛10，然后酸处理中间螺环亚胺8。
• RUBIRALTA, MARIO;DIEZ, ANNA;VILA, CRISTINA, TETRAHEDRON LETT., 31,(1990) N6, C. 3779-3782
  作者：RUBIRALTA, MARIO、DIEZ, ANNA、VILA, CRISTINA

  DOI：——

  日期：——
• RUBIRALTA, MARIO;DIEZ, ANNA;VILA, CRISTINA, TETRAHEDRON, 46,(1990) N2, C. 4443-4456
  作者：RUBIRALTA, MARIO、DIEZ, ANNA、VILA, CRISTINA

  DOI：——

  日期：——
• Pesticidal mixtures comprising a pyrazole compound
  申请人：BASF SE

  公开号：US20170035050A1

  公开（公告）日：2017-02-09

  The present invention relates to pesticidal mixtures comprising as active compounds 1) at least one pyrazole compound A selected from the compounds of formula I: wherein the variables have the meaning as defined in the description, and 2) at least one further compound B selected from the compounds of the following groups A.1, A.2, A.3, A.4, A.5, A.6, A.7, A.8, A.9, A.10, A.11, A.12, A.13, A.14, A.15, A.16, A.17, F.1, F.2, F.3, F.4, F.5, F.6, F.7, F.8, F.9, F.10 and F.11 as defined in the specification. The present invention also relates to novel pyrazole compounds of the formula I. The present invention also relates to methods and use of these mixtures and novel compounds for combating invertebrate pests such as insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests, especially also for protecting plant propagation material as like seeds.
• Synthetic applications of protected 2-aryl-4-piperidones. 7. Synthesis of 1-ethylindolo[2,3-a]quinolizidin-2-one
  作者：Mario Rubiralta、Anna Diez、Cristina Vila、Yves Troin、Miguel Feliz

  DOI：10.1021/jo00022a015

  日期：1991.10

  The synthesis of 1-ethylindolo[2,3-a]quinolizidin-2-one (1) by the intramolecular cyclization of protected N-(2-hydroxyethyl)-2-[1-(phenylsulfonyl)-3-indolyl]-4-piperidone 15 by the action of K(t)BuO and further acid treatment is reported. The methodology has been first carried out for its deethyl analogue 2 from (hydroxyethyl)piperidine 14 and has shown to be a good general method to reach indolo[2,3-a]quinolizidin-2-one systems. Compound 1 has also been obtained by an unusual rearrangement in acidic medium of 7-ethylhexahydropyrido[1',2':1,2]pyrazino[4,3-a]indole.